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talk page for discussing improvements to the
Deep vein thrombosis article. This is not a forum for general discussion of the article's subject. |
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![]() | Ideal sources for Wikipedia's health content are defined in the guideline
Wikipedia:Identifying reliable sources (medicine) and are typically
review articles. Here are links to possibly useful sources of information about Deep vein thrombosis.
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{{dashboard.wikiedu.org assignment | course = Wikipedia:Wiki_Ed/Grand_Valley_State_University/Nursing_265_Introduction_to_Nursing_Research_and_Evidence-Based_Practice_(Fall_2017) | reviewers = [[User:Williann1|Williann1]] }}
As part of a student assignment, feedback on DVT was posted on a user's talk page: [1]. I believe I have already addressed their concerns with regard to compression stockings, but I'll double check. Biosthmors ( talk) 17:13, 30 December 2019 (UTC)
I think that "deep bone thrombosis" ( dbt) is the same thing as deep vein thrombosis. I'm not sure, but here is some corroborating text:
About 297 results (0.27 seconds) Search Results Featured snippet from the web Deep bone thrombosis, which is clotting in the veins that can cause a range of leg pain – this can become a life threatening illness if not addressed. ... Other symptoms of PAD include: numbness/tingling in the lower legs and feet. coldness in the lower legs and feet. ulcers or sores on the legs or feet that do not heal. Leg Pain https://www.viralegs.com › leg-pain Web results Causes of Deep Bone Thrombosis - Graphic Online https://www.graphic.com.gh › Ghana news Headlines › Health May 2, 2014 - Dear mirror doctor I am a very active 46-year-old man who drives to and from work with no problems. I noticed a gradual increase in the size of ... Assessment 2 (1) | Thrombosis | Vein - Scribd https://www.scribd.com › document › Assessment-2-1 Nov 20, 2017 - Deep vein thrombosis deep bone thrombosis (DVT) is a blood clot thrombosis in a major vein that usually develops in the legs and/or pelvis. 2. Deep Vein Thrombosis - Its a real issue if you drive too much ... https://uberpeople.net › Geographical › Australia › Sydney Feb 21, 2016 - 20 posts - 18 authors ... abuse prescription drugs and are actually obese telling us all we have to live healthier. On the Deep bone Thrombosis thing just make sure if ... Leg Pain https://www.viralegs.com › leg-pain Deep bone thrombosis, which is clotting in the veins that can cause a range of leg pain – this can become a life threatening illness if not addressed. Myumaimah : http://myumaimah.com/ https://myumaimah.com.cutestat.com ... wear compression stockings, compression socks for sale, deep bone thrombosis, varicose vein clinic, jobst compression socks, vertical veins in legs, where to ... The House That Hugh Laurie Built: An Unauthorized Biography ... https://books.google.com › books Paul Challen - 2010 - Biography & Autobiography Within a minute in their first diagnostic session, House has ruled out the schizophrenia as a cause of the deep bone thrombosis (dbt). Unlike his other patients, ... Deep Bone Thrombosis is Sexy | Torn Flesh Records https://tornfleshrecords.bandcamp.com › track › deep-bone-thrombosis-is-... Deep Bone Thrombosis is Sexy by Torn Flesh Records, released 18 November 2013. Cafe on the Edge of Outer Space - Page 1 - Google Books Result https://books.google.com › books Robert Appleton - 2008 - Interstellar travel It's a deep-bone thrombosis of stars and gravitational attraction. Body to body, orbit to orbit, me to her. We're cosmic trespassers, and I feel just as transparent as ... The Complete Testament - Page 1011 - Google Books Result https://books.google.com › books BLA BLA BLA, WE COULD NOT STOP GIVING HIM HIS MEDICATION EVEN HE IS SHOWING SIGNS OF DEEP BONE THROMBOSIS, BUT BECAUSE WE ... Dr. Sunder Narasimhan - General Surgeon - Book ... - Practo https://www.practo.com › bangalore › doctor › sunder-narasimhan-vascula... Rating: 88% - 154 votes - Price range: ₹700 consultation fee Filter placement for deep bone thrombosis. ○. Cerucial rib. ○. Thoracic Outlet Syndrome. ○. Arterial Duroubosis. ○. Arterial Occlusion. ○. Mesentric Ischemia.
From https://www.google.com/search?client=firefox-b-1-d&q=%22Deep+bone+thrombosis%22 -- User123o987name ( talk) 16:21, 31 December 2019 (UTC)
Greetings User:Graham Beards. After a long hiatus, I am back to working on this article, which you previously reviewed. Thank you. Because of your comment towards the bottom of Wikipedia:Peer review/Deep vein thrombosis/archive3, I did recently incorporate mention of stroke [2] and I have been researching the potential impact of heart failure. Regarding heart failure as a risk factor for DVT, I am not yet sure. My current opinion is limited by general internet access. A 2016 systematic review and meta-analysis ( doi: 10.1016/S2352-3026(15)00228-8), for example, states in the abstract "Many studies have investigated the association between venous thromboembolism and heart failure, but have yielded inconsistent findings" but then concludes "Heart failure is a common independent risk factor for venous thromboembolism". Yet it seems odd to cite this article to support the claim that heart failure is a risk factor for DVT because this study is limited to hospitalized patients, and hospitalization itself is already cited on the article as a DVT risk factor. Also, it could be the case that statistical significance for VTE is demonstrated by pooling DVT and PE data while the statistical significance for DVT might not yet be independently established. Similarly, I saw a 2019 study [3] where heart failure appears more correlated with isolated PE than DVT with or without PE, called DVT/PE in this study. While the 2016 meta-analysis suggested that their findings could be considered in future prophylaxis regimens, for what it's worth, the most recent 2018 clinical practice guidelines [4] (that the CDC prominently features on their website [5]) don't have any separate guidance on heart failure patients. I feel a bit lost in the weeds here, but at this point it doesn't seem like a firm fact to call heart failure a risk factor for DVT (unless we operate under the assumption that VTE risk factors are always DVT risk factors). So, should VTE risk factors be cited on the DVT article as DVT risk factors? Biosthmors ( talk) 17:07, 2 January 2020 (UTC)
Perhaps we should just specify that the risk factors in this article are VTE risk factors and then that fixes this issue. Biosthmors ( talk) 17:36, 2 January 2020 (UTC)
{{
cite journal}}
: CS1 maint: unflagged free DOI (
link) however (
Annals of Translational Medicine redirects to
AME Publishing Company which currently says "It was included on Beall's list of predatory publishers, prior to the list being taken offline in January 2017")I am currently not sure if all authors are consistent with their definition for iliofemoral DVT. It appears it might either mean proximal DVT,(I previously cited doi: 10.1016/S0140-6736(11)61875-8 to support this use but I'm now paywalled), a certain kind of bad proximal DVT that requires involvement of an iliac vein, [7], or something to be distingished from both femoropopliteal and distal DVT. [8] To be determined. Biosthmors ( talk) 19:54, 20 January 2020 (UTC)
(Relevant diff, which I reverted.) I massively reworked the newly dubbed "Causes and risk factors" section yesterday by subsuming a risk factor subsection into the prose of the causes section. So I renamed the new mega-section "Causes and risk factors." I think this title works better than just picking one (Causes or Risk factors) because the first paragraph is all about causes and a lot of the prose talks about the interplay between specific risk factors and why they contribute to those causes. So in my mind the dual titles work well for this section. That being said, the article is in flux, and there's conceptual overlap with the aforementioned section and the Pathophysiology section. So maybe we'll ultimately find a new and improved re-organization of the text that makes this thread obsolete. Also, maybe I'm missing some collective wisdom. For what it's worth, it does seem like a sentence should be added that explains how DVT risk is conceptualized as multifactorial and begins once a threshold is reached. I recall seeing that in a review article, but I'm not sure if it is cited or not. Biosthmors ( talk) 15:46, 28 January 2020 (UTC)
Bed rest appears to be confined to the history books: "The second half of the [20th] century was characterized by the simplification of anticoagulant treatment, which allowed ambulatory treatment of the disease and the end of the bed‐rest dogma". [9] This explains why I trimmed [10] that content out of the treatment section, which was based on 10+ year old medical sources anyhow. The article already establishes that bed rest is a risk factor (causes section) and that walking helps (prevention section). There's plenty of room to discuss bed rest as a historical treatment in the historical section, as the above quoted source does. But there's no need for us to carp to a few hold-out physicians of the 1990s, as it appears the former text was trying to do. Biosthmors ( talk) 18:36, 4 February 2020 (UTC)
I cited a recent secondary source for content regarding aspirin. The following studies were previously cited in the DVT article, but I commented them out a while back, and I'm not sure we need to cite them. Perhaps listing them here will help make sure the article is comprehensive:
Biosthmors ( talk) 15:50, 18 February 2020 (UTC)
Is still commonly used especially in regions that do not have access to newer / more expensive agents. It is still an appropriate treatment and thus IMO should remain mention as such in the lead. Doc James ( talk · contribs · email) 20:34, 26 February 2020 (UTC)
Guideline updated here. Need to review references to CG144 and replace. JFW | T@lk 09:57, 5 May 2020 (UTC)
A discussion is taking place to address the redirect
Deep vein thrombosis in lower limb (NOS). The discussion will occur at
Wikipedia:Redirects for discussion/Log/2020 July 13#Deep vein thrombosis in lower limb (NOS) until a consensus is reached, and readers of this page are welcome to contribute to the discussion.
Tom (LT) (
talk)
06:58, 13 July 2020 (UTC)
Here we can list sources that might be useful for an updated pathophysiology section:
{{
cite journal}}
: CS1 maint: unflagged free DOI (
link)
{{
cite journal}}
: CS1 maint: unflagged free DOI (
link){{
cite journal}}
: CS1 maint: unflagged free DOI (
link)
Biosthmors ( talk) 21:36, 14 August 2020 (UTC)
Epidemiology:
Series of articles in Blood:
Random:
{{
cite web}}
: CS1 maint: url-status (
link)Diagnosis:
{{
cite journal}}
: CS1 maint: unflagged free DOI (
link)Signs and symptoms:
Lines of Zahn:
Biosthmors ( talk) 19:26, 17 March 2021 (UTC)
A recent edit [14] added the following text, which I just removed as I have concerns over too-close paraphrasing and duplicative content. Some of it however might be worth adding back "Venous blood clots are structures consisting of successive layers of fibrin, platelets, red bloods cells, and leukocytes. Compared to arterial clots, the number of platelets is relatively low, but platelets do seem to play an important role. It's also worth noting that the use of aspirin may decrease the risk of first and recurrent VTE." Biosthmors ( talk) 17:20, 2 April 2021 (UTC)
This edit might have removed the answer but I haven't seen it discussed yet in more recent reviews. Biosthmors ( talk) 18:39, 9 April 2021 (UTC)
In reply to this edit, I've seen a couple reviews mention soleal veins [15] / the soleal vein [16]. The second source discusses the soleal vein in depth. I thought mention of this vein / venous system and a WP:REDlink to it were appropriate. I was thinking since secondary sources mention it, we'd be fine to mention it as well (and that it deserved an article) User:Jfdwolff. Thanks. Biosthmors ( talk) 14:42, 11 April 2021 (UTC)
I excised the following text: Anticoagulation, which increases the risk of bleeding, is sometimes used indefinitely (lifelong treatment) in those with a high-risk for recurrence. The risk of major bleeding with long-term anticoagulation is about 3% per year,<ref name="Varga"/> and the point where annual VTE risk is thought to warrant long-term anticoagulation is estimated to be between 3 and 9%.<ref name="Keeling"/> Usually, only when individuals exceed a 9% annual VTE risk is long-term anticoagulation a common consideration.<ref name="Keeling">{{cite journal | vauthors = Keeling D, Baglin T, Tait C, Watson H, Perry D, Baglin C, Kitchen S, Makris M | display-authors = 6 | title = Guidelines on oral anticoagulation with warfarin – fourth edition | journal = British Journal of Haematology | volume = 154 | issue = 3 | pages = 311–24 | date = August 2011 | pmid = 21671894 | doi = 10.1111/j.1365-2141.2011.08753.x | doi-access=free}}</ref> For example, antithrombin deficiency, a strong or moderately strong risk factor, carries an annual risk of VTE of only 0.8–1.5%;<ref name="Varga"/> as such, asymptomatic individuals with thrombophilia do not warrant long-term anticoagulation.<ref>[[#CITEREFGuyattAklCrowtherGutterman2012|Guyatt et al. 2012]], p. 11S: 7.1.</ref>
The logic of this text is predominantly based upon the use of warfarin. However, anticoagulation now, warfarin or DOACs, has more complicated and differing risk profiles. For example: "... the consequences of a major bleed are generally worse than the consequences of a recurrent VTE: about 12% of major bleeds (probably lower with direct oral anticoagulants [DOACs] than with warfarin10 ), as opposed to 4% of recurrent VTE, are fatal (∼3:1 ratio).3,9,11-13" From
[17].
Biosthmors (
talk)
06:33, 16 April 2021 (UTC)
I removed the following: Signs and symptoms alone are not sufficiently [[Sensitivity and specificity|sensitive or specific]] to make a diagnosis, but when considered in conjunction with [[#Diagnosis|pre-test probability]], can help determine the likelihood of DVT.<ref name=2019Tran/>
and simplified the content for the signs and symptoms section. I'm currently thinking the diagnosis section should mention and link
pre-test probability at the beginning.
Biosthmors (
talk)
15:38, 22 April 2021 (UTC)
The page refers to VTE that can relate to either DVT or PE which is backed up by ref used, but other refs and the entry page for VTE says that VTE is the combination of DVT and PE. This needs to be addressed maybe by adding 'some sources...' etc. -- Iztwoz ( talk) 09:50, 25 April 2021 (UTC)
Prompted by
Wikipedia:Peer review/Deep vein thrombosis/archive4, I removed the following text from the Classification section because I think it wouldn't be useful for readers. These distinctions are either hardly drawn or absent in the article: DVT that has no symptoms, but is found only by screening, is labeled asymptomatic or incidental.<ref name=airline/><ref name=2020Mulder>{{cite journal | vauthors = Mulder FI, Di Nisio M, Ay C, Carrier M, ((Bosch FTM)), Segers A, Kraaijpoel N, Grosso MA, Zhang G, Verhamme P, Wang TF, Weitz JI, Middeldorp S, Raskob G, ((Beenen LFM)), Büller HR, van Es N | display-authors = 6 | title = Clinical implications of incidental venous thromboembolism in cancer patients | journal = The European Respiratory Journal | volume = 55 | issue = 2 | pages = | date = February 2020 | pmid = 31727694 | doi = 10.1183/13993003.01697-2019 }}</ref>
And this will be a good source to help give context to the different classifications of proximal DVT: Jenkins JS, Michael P (2014). "Deep venous thrombosis: an interventionalist's approach". The Ochsner Journal. 14 (4): 633–40. PMC 4295740. PMID 25598728. Biosthmors ( talk) 14:27, 13 May 2021 (UTC)
Pregnancy is associated with an increase in fibrinogen and D-dimer levels, so this test is less useful. This should probably be mentioned in the diagnosis section. I've heard of age-adjusted D-dimer levels in the workup of PE, but I don't recall ever seeing that applied to DVT. Biosthmors ( talk) 17:52, 25 May 2021 (UTC)
I'm not sure this addition adds anything to the article. It's 9 years old, so it's likely outdated, and it doesn't add anything to the article in my opinion. I seriously doubt the recent seminar on VTE in the Lancet cited this article. The questions Cochrane articles attempt to answer (in my opinion) don't often cleanly lend themselves towards generating useful prose. This article has only been cited ~24 times in the last 9 years. Others seem to agree. Biosthmors ( talk) 02:10, 4 August 2021 (UTC)
Selective estrogen receptor modulators can be added as a risk factor. Biosthmors ( talk) 22:04, 1 August 2022 (UTC)
An expert told me HHS was a risk factor today. I see it confirmed in Western populations thus far. [22] Biosthmors ( talk) 23:38, 4 November 2022 (UTC)
This is the
talk page for discussing improvements to the
Deep vein thrombosis article. This is not a forum for general discussion of the article's subject. |
Article policies
|
Find medical sources: Source guidelines · PubMed · Cochrane · DOAJ · Gale · OpenMD · ScienceDirect · Springer · Trip · Wiley · TWL |
Archives: 1 |
![]() | Deep vein thrombosis has been listed as one of the Natural sciences good articles under the good article criteria. If you can improve it further, please do so. If it no longer meets these criteria, you can reassess it. | ||||||||||||||||||||||||
|
![]() | This article is rated GA-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | |||||||||||||||||||||||||||||
|
![]() | Ideal sources for Wikipedia's health content are defined in the guideline
Wikipedia:Identifying reliable sources (medicine) and are typically
review articles. Here are links to possibly useful sources of information about Deep vein thrombosis.
|
{{dashboard.wikiedu.org assignment | course = Wikipedia:Wiki_Ed/Grand_Valley_State_University/Nursing_265_Introduction_to_Nursing_Research_and_Evidence-Based_Practice_(Fall_2017) | reviewers = [[User:Williann1|Williann1]] }}
As part of a student assignment, feedback on DVT was posted on a user's talk page: [1]. I believe I have already addressed their concerns with regard to compression stockings, but I'll double check. Biosthmors ( talk) 17:13, 30 December 2019 (UTC)
I think that "deep bone thrombosis" ( dbt) is the same thing as deep vein thrombosis. I'm not sure, but here is some corroborating text:
About 297 results (0.27 seconds) Search Results Featured snippet from the web Deep bone thrombosis, which is clotting in the veins that can cause a range of leg pain – this can become a life threatening illness if not addressed. ... Other symptoms of PAD include: numbness/tingling in the lower legs and feet. coldness in the lower legs and feet. ulcers or sores on the legs or feet that do not heal. Leg Pain https://www.viralegs.com › leg-pain Web results Causes of Deep Bone Thrombosis - Graphic Online https://www.graphic.com.gh › Ghana news Headlines › Health May 2, 2014 - Dear mirror doctor I am a very active 46-year-old man who drives to and from work with no problems. I noticed a gradual increase in the size of ... Assessment 2 (1) | Thrombosis | Vein - Scribd https://www.scribd.com › document › Assessment-2-1 Nov 20, 2017 - Deep vein thrombosis deep bone thrombosis (DVT) is a blood clot thrombosis in a major vein that usually develops in the legs and/or pelvis. 2. Deep Vein Thrombosis - Its a real issue if you drive too much ... https://uberpeople.net › Geographical › Australia › Sydney Feb 21, 2016 - 20 posts - 18 authors ... abuse prescription drugs and are actually obese telling us all we have to live healthier. On the Deep bone Thrombosis thing just make sure if ... Leg Pain https://www.viralegs.com › leg-pain Deep bone thrombosis, which is clotting in the veins that can cause a range of leg pain – this can become a life threatening illness if not addressed. Myumaimah : http://myumaimah.com/ https://myumaimah.com.cutestat.com ... wear compression stockings, compression socks for sale, deep bone thrombosis, varicose vein clinic, jobst compression socks, vertical veins in legs, where to ... The House That Hugh Laurie Built: An Unauthorized Biography ... https://books.google.com › books Paul Challen - 2010 - Biography & Autobiography Within a minute in their first diagnostic session, House has ruled out the schizophrenia as a cause of the deep bone thrombosis (dbt). Unlike his other patients, ... Deep Bone Thrombosis is Sexy | Torn Flesh Records https://tornfleshrecords.bandcamp.com › track › deep-bone-thrombosis-is-... Deep Bone Thrombosis is Sexy by Torn Flesh Records, released 18 November 2013. Cafe on the Edge of Outer Space - Page 1 - Google Books Result https://books.google.com › books Robert Appleton - 2008 - Interstellar travel It's a deep-bone thrombosis of stars and gravitational attraction. Body to body, orbit to orbit, me to her. We're cosmic trespassers, and I feel just as transparent as ... The Complete Testament - Page 1011 - Google Books Result https://books.google.com › books BLA BLA BLA, WE COULD NOT STOP GIVING HIM HIS MEDICATION EVEN HE IS SHOWING SIGNS OF DEEP BONE THROMBOSIS, BUT BECAUSE WE ... Dr. Sunder Narasimhan - General Surgeon - Book ... - Practo https://www.practo.com › bangalore › doctor › sunder-narasimhan-vascula... Rating: 88% - 154 votes - Price range: ₹700 consultation fee Filter placement for deep bone thrombosis. ○. Cerucial rib. ○. Thoracic Outlet Syndrome. ○. Arterial Duroubosis. ○. Arterial Occlusion. ○. Mesentric Ischemia.
From https://www.google.com/search?client=firefox-b-1-d&q=%22Deep+bone+thrombosis%22 -- User123o987name ( talk) 16:21, 31 December 2019 (UTC)
Greetings User:Graham Beards. After a long hiatus, I am back to working on this article, which you previously reviewed. Thank you. Because of your comment towards the bottom of Wikipedia:Peer review/Deep vein thrombosis/archive3, I did recently incorporate mention of stroke [2] and I have been researching the potential impact of heart failure. Regarding heart failure as a risk factor for DVT, I am not yet sure. My current opinion is limited by general internet access. A 2016 systematic review and meta-analysis ( doi: 10.1016/S2352-3026(15)00228-8), for example, states in the abstract "Many studies have investigated the association between venous thromboembolism and heart failure, but have yielded inconsistent findings" but then concludes "Heart failure is a common independent risk factor for venous thromboembolism". Yet it seems odd to cite this article to support the claim that heart failure is a risk factor for DVT because this study is limited to hospitalized patients, and hospitalization itself is already cited on the article as a DVT risk factor. Also, it could be the case that statistical significance for VTE is demonstrated by pooling DVT and PE data while the statistical significance for DVT might not yet be independently established. Similarly, I saw a 2019 study [3] where heart failure appears more correlated with isolated PE than DVT with or without PE, called DVT/PE in this study. While the 2016 meta-analysis suggested that their findings could be considered in future prophylaxis regimens, for what it's worth, the most recent 2018 clinical practice guidelines [4] (that the CDC prominently features on their website [5]) don't have any separate guidance on heart failure patients. I feel a bit lost in the weeds here, but at this point it doesn't seem like a firm fact to call heart failure a risk factor for DVT (unless we operate under the assumption that VTE risk factors are always DVT risk factors). So, should VTE risk factors be cited on the DVT article as DVT risk factors? Biosthmors ( talk) 17:07, 2 January 2020 (UTC)
Perhaps we should just specify that the risk factors in this article are VTE risk factors and then that fixes this issue. Biosthmors ( talk) 17:36, 2 January 2020 (UTC)
{{
cite journal}}
: CS1 maint: unflagged free DOI (
link) however (
Annals of Translational Medicine redirects to
AME Publishing Company which currently says "It was included on Beall's list of predatory publishers, prior to the list being taken offline in January 2017")I am currently not sure if all authors are consistent with their definition for iliofemoral DVT. It appears it might either mean proximal DVT,(I previously cited doi: 10.1016/S0140-6736(11)61875-8 to support this use but I'm now paywalled), a certain kind of bad proximal DVT that requires involvement of an iliac vein, [7], or something to be distingished from both femoropopliteal and distal DVT. [8] To be determined. Biosthmors ( talk) 19:54, 20 January 2020 (UTC)
(Relevant diff, which I reverted.) I massively reworked the newly dubbed "Causes and risk factors" section yesterday by subsuming a risk factor subsection into the prose of the causes section. So I renamed the new mega-section "Causes and risk factors." I think this title works better than just picking one (Causes or Risk factors) because the first paragraph is all about causes and a lot of the prose talks about the interplay between specific risk factors and why they contribute to those causes. So in my mind the dual titles work well for this section. That being said, the article is in flux, and there's conceptual overlap with the aforementioned section and the Pathophysiology section. So maybe we'll ultimately find a new and improved re-organization of the text that makes this thread obsolete. Also, maybe I'm missing some collective wisdom. For what it's worth, it does seem like a sentence should be added that explains how DVT risk is conceptualized as multifactorial and begins once a threshold is reached. I recall seeing that in a review article, but I'm not sure if it is cited or not. Biosthmors ( talk) 15:46, 28 January 2020 (UTC)
Bed rest appears to be confined to the history books: "The second half of the [20th] century was characterized by the simplification of anticoagulant treatment, which allowed ambulatory treatment of the disease and the end of the bed‐rest dogma". [9] This explains why I trimmed [10] that content out of the treatment section, which was based on 10+ year old medical sources anyhow. The article already establishes that bed rest is a risk factor (causes section) and that walking helps (prevention section). There's plenty of room to discuss bed rest as a historical treatment in the historical section, as the above quoted source does. But there's no need for us to carp to a few hold-out physicians of the 1990s, as it appears the former text was trying to do. Biosthmors ( talk) 18:36, 4 February 2020 (UTC)
I cited a recent secondary source for content regarding aspirin. The following studies were previously cited in the DVT article, but I commented them out a while back, and I'm not sure we need to cite them. Perhaps listing them here will help make sure the article is comprehensive:
Biosthmors ( talk) 15:50, 18 February 2020 (UTC)
Is still commonly used especially in regions that do not have access to newer / more expensive agents. It is still an appropriate treatment and thus IMO should remain mention as such in the lead. Doc James ( talk · contribs · email) 20:34, 26 February 2020 (UTC)
Guideline updated here. Need to review references to CG144 and replace. JFW | T@lk 09:57, 5 May 2020 (UTC)
A discussion is taking place to address the redirect
Deep vein thrombosis in lower limb (NOS). The discussion will occur at
Wikipedia:Redirects for discussion/Log/2020 July 13#Deep vein thrombosis in lower limb (NOS) until a consensus is reached, and readers of this page are welcome to contribute to the discussion.
Tom (LT) (
talk)
06:58, 13 July 2020 (UTC)
Here we can list sources that might be useful for an updated pathophysiology section:
{{
cite journal}}
: CS1 maint: unflagged free DOI (
link)
{{
cite journal}}
: CS1 maint: unflagged free DOI (
link){{
cite journal}}
: CS1 maint: unflagged free DOI (
link)
Biosthmors ( talk) 21:36, 14 August 2020 (UTC)
Epidemiology:
Series of articles in Blood:
Random:
{{
cite web}}
: CS1 maint: url-status (
link)Diagnosis:
{{
cite journal}}
: CS1 maint: unflagged free DOI (
link)Signs and symptoms:
Lines of Zahn:
Biosthmors ( talk) 19:26, 17 March 2021 (UTC)
A recent edit [14] added the following text, which I just removed as I have concerns over too-close paraphrasing and duplicative content. Some of it however might be worth adding back "Venous blood clots are structures consisting of successive layers of fibrin, platelets, red bloods cells, and leukocytes. Compared to arterial clots, the number of platelets is relatively low, but platelets do seem to play an important role. It's also worth noting that the use of aspirin may decrease the risk of first and recurrent VTE." Biosthmors ( talk) 17:20, 2 April 2021 (UTC)
This edit might have removed the answer but I haven't seen it discussed yet in more recent reviews. Biosthmors ( talk) 18:39, 9 April 2021 (UTC)
In reply to this edit, I've seen a couple reviews mention soleal veins [15] / the soleal vein [16]. The second source discusses the soleal vein in depth. I thought mention of this vein / venous system and a WP:REDlink to it were appropriate. I was thinking since secondary sources mention it, we'd be fine to mention it as well (and that it deserved an article) User:Jfdwolff. Thanks. Biosthmors ( talk) 14:42, 11 April 2021 (UTC)
I excised the following text: Anticoagulation, which increases the risk of bleeding, is sometimes used indefinitely (lifelong treatment) in those with a high-risk for recurrence. The risk of major bleeding with long-term anticoagulation is about 3% per year,<ref name="Varga"/> and the point where annual VTE risk is thought to warrant long-term anticoagulation is estimated to be between 3 and 9%.<ref name="Keeling"/> Usually, only when individuals exceed a 9% annual VTE risk is long-term anticoagulation a common consideration.<ref name="Keeling">{{cite journal | vauthors = Keeling D, Baglin T, Tait C, Watson H, Perry D, Baglin C, Kitchen S, Makris M | display-authors = 6 | title = Guidelines on oral anticoagulation with warfarin – fourth edition | journal = British Journal of Haematology | volume = 154 | issue = 3 | pages = 311–24 | date = August 2011 | pmid = 21671894 | doi = 10.1111/j.1365-2141.2011.08753.x | doi-access=free}}</ref> For example, antithrombin deficiency, a strong or moderately strong risk factor, carries an annual risk of VTE of only 0.8–1.5%;<ref name="Varga"/> as such, asymptomatic individuals with thrombophilia do not warrant long-term anticoagulation.<ref>[[#CITEREFGuyattAklCrowtherGutterman2012|Guyatt et al. 2012]], p. 11S: 7.1.</ref>
The logic of this text is predominantly based upon the use of warfarin. However, anticoagulation now, warfarin or DOACs, has more complicated and differing risk profiles. For example: "... the consequences of a major bleed are generally worse than the consequences of a recurrent VTE: about 12% of major bleeds (probably lower with direct oral anticoagulants [DOACs] than with warfarin10 ), as opposed to 4% of recurrent VTE, are fatal (∼3:1 ratio).3,9,11-13" From
[17].
Biosthmors (
talk)
06:33, 16 April 2021 (UTC)
I removed the following: Signs and symptoms alone are not sufficiently [[Sensitivity and specificity|sensitive or specific]] to make a diagnosis, but when considered in conjunction with [[#Diagnosis|pre-test probability]], can help determine the likelihood of DVT.<ref name=2019Tran/>
and simplified the content for the signs and symptoms section. I'm currently thinking the diagnosis section should mention and link
pre-test probability at the beginning.
Biosthmors (
talk)
15:38, 22 April 2021 (UTC)
The page refers to VTE that can relate to either DVT or PE which is backed up by ref used, but other refs and the entry page for VTE says that VTE is the combination of DVT and PE. This needs to be addressed maybe by adding 'some sources...' etc. -- Iztwoz ( talk) 09:50, 25 April 2021 (UTC)
Prompted by
Wikipedia:Peer review/Deep vein thrombosis/archive4, I removed the following text from the Classification section because I think it wouldn't be useful for readers. These distinctions are either hardly drawn or absent in the article: DVT that has no symptoms, but is found only by screening, is labeled asymptomatic or incidental.<ref name=airline/><ref name=2020Mulder>{{cite journal | vauthors = Mulder FI, Di Nisio M, Ay C, Carrier M, ((Bosch FTM)), Segers A, Kraaijpoel N, Grosso MA, Zhang G, Verhamme P, Wang TF, Weitz JI, Middeldorp S, Raskob G, ((Beenen LFM)), Büller HR, van Es N | display-authors = 6 | title = Clinical implications of incidental venous thromboembolism in cancer patients | journal = The European Respiratory Journal | volume = 55 | issue = 2 | pages = | date = February 2020 | pmid = 31727694 | doi = 10.1183/13993003.01697-2019 }}</ref>
And this will be a good source to help give context to the different classifications of proximal DVT: Jenkins JS, Michael P (2014). "Deep venous thrombosis: an interventionalist's approach". The Ochsner Journal. 14 (4): 633–40. PMC 4295740. PMID 25598728. Biosthmors ( talk) 14:27, 13 May 2021 (UTC)
Pregnancy is associated with an increase in fibrinogen and D-dimer levels, so this test is less useful. This should probably be mentioned in the diagnosis section. I've heard of age-adjusted D-dimer levels in the workup of PE, but I don't recall ever seeing that applied to DVT. Biosthmors ( talk) 17:52, 25 May 2021 (UTC)
I'm not sure this addition adds anything to the article. It's 9 years old, so it's likely outdated, and it doesn't add anything to the article in my opinion. I seriously doubt the recent seminar on VTE in the Lancet cited this article. The questions Cochrane articles attempt to answer (in my opinion) don't often cleanly lend themselves towards generating useful prose. This article has only been cited ~24 times in the last 9 years. Others seem to agree. Biosthmors ( talk) 02:10, 4 August 2021 (UTC)
Selective estrogen receptor modulators can be added as a risk factor. Biosthmors ( talk) 22:04, 1 August 2022 (UTC)
An expert told me HHS was a risk factor today. I see it confirmed in Western populations thus far. [22] Biosthmors ( talk) 23:38, 4 November 2022 (UTC)