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Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT ( talk) 17:56, 16 January 2022 (UTC)
The article seems to say the same thing twice--about vitamins being organic and coenzymes.
Pasted from the disambig over at cofactor, some material could be integrated here:
Cofactor:a small, non-protein molecule or ion that is bound in the functional site of a protein and assists in ligand binding or catalysis or both. Some cofactors are bound covalently, others are not. For example, prosthetic groups and compounds such as NAD, NADP, flavin nucleotides, coenzyme A.
If anyone has time, the {{ Enzyme cofactors}} template would really benefit from your expertise. Thanks! :) Willow 19:11, 27 January 2007 (UTC)
Just FYI, here are examples of articles using the term in the broader sense I indicate in this section:
http://mcb.asm.org/cgi/content/abstract/22/6/1626 http://www.ncbi.nlm.nih.gov/pubmed/15860367 http://www.nature.com/nature/journal/v398/n6730/full/398824a0.html
Jbening ( talk) 00:48, 16 October 2008 (UTC)
I deleted the figure, because I do not what it shows, but I clearly know that succinate dehydrogenase is the typical example of an oxidoreductase that is NOT a heme protein, but an iron suflur protein. This can be verified in any biochemical textbook.
Lulubou ( talk) 09:42, 9 March 2009 (UTC)
Yes, that one looks nice. Lulubou ( talk) 18:35, 9 March 2009 (UTC)
The picture seems to show that succinate and FAD enters during the same reaction cycle. Doesn't FAD enter much earlier and stay for several reactions? Narayanese ( talk) 07:50, 11 March 2009 (UTC)
FAD is covalently bound in succinate dehydrogenase
Lulubou ( talk) 11:38, 11 March 2009 (UTC)
Great !. Good idea to merge the articles on cofactors, coenzymes and prosthetic groups. I have not yet looked at the details, but the article looks great and well structured.
I am just wondering, if those readers that are redirected from the terms ”coenzyme” and ”prosthetic group” mightl not be frustrated when they do not see these terms immediately. Maybe it would be good to add them in the title that could run : Cofactors, coenzymes and prosthetic groups. It would be nice if the terms "coenzymes" and "prosthetic group" already appear in the introduction with a small explanation.
Lulubou ( talk) 11:38, 11 March 2009 (UTC)
This article uses the term thiamine diphosphate (ThDP) and the article to which it links is titled thiamine pyrophosphate (TPP), but acknowledges the alternative term . I know it is a matter of in which enzymology circles you roam, but should we be internally consistent and call it TPP in this cofactors article? The problem I have with thiamine diphosphate is some people (a rather famous enzymologist included) abbreviate it TDP, and that gets confused with the thymidine diphosphate. Pdcook ( talk) 15:38, 9 October 2009 (UTC)
ApoC-II and apoA-I are protein cofactors for lipoprotein lipase (LPL) & lecithin-cholesterol acyltransferase (LCAT), respectively. I just linked the word "cofactor" in that article to this article, but the first thing this article says is contradictory to the function of these two apolipoproteins. What's up? Dcs002 ( talk) 23:24, 18 July 2010 (UTC)
Several glutathione analogs are not yet discussed, including mycothiol, bacillithiol, and trypanothione.
Chlorophyll deserves to be discussed as a cofactor.
The page also should mention that a number of cofactors (e.g. heme) exist in a variety of forms. — Preceding unsigned comment added by Daniel haft ( talk • contribs) 16:09, 19 March 2012 (UTC)
Either one must be false. Please correct. -- 78.50.190.114 ( talk) 16:53, 12 December 2012 (UTC)
The first paragraph states that "A cofactor is a non-protein chemical compound that is bound to a protein..." and the second paragraph states that "Cofactors can be classified depending on how tightly they bind to an enzyme...". These would seem to be in conflict. Are cofactors things that bind to protiens or bind to enzymes or is it both?
The comment(s) below were originally left at Talk:Cofactor (biochemistry)/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.
Changed rating to "high" as this is high school/SAT biology content. - tameeria 21:45, 18 February 2007 (UTC) |
Last edited at 21:45, 18 February 2007 (UTC). Substituted at 11:59, 29 April 2016 (UTC)
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Hello Boghog,
Currently, Coenzyme is redirected to Cofactor.
I think that Coenzyme should stand by itself. I am willing to re-edit the entries. But, before I start working on this I would like to hear your opinion on the subject.
Rationale, Cofactor entry is currently too long. Coenzyme deserves an entry by itself.
Please inform what you think on this.
Genewiki1 ( talk) 15:28, 11 February 2018 (UTC)
Where do "protein-derived cofactors" fit in the types of cofactors in the introduction? kupirijo ( talk) 13:00, 3 October 2023 (UTC)
![]() | This article is rated B-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | |||||||||||||
|
This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available
on the course page. Student editor(s):
Sarahnkov.
Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT ( talk) 17:56, 16 January 2022 (UTC)
The article seems to say the same thing twice--about vitamins being organic and coenzymes.
Pasted from the disambig over at cofactor, some material could be integrated here:
Cofactor:a small, non-protein molecule or ion that is bound in the functional site of a protein and assists in ligand binding or catalysis or both. Some cofactors are bound covalently, others are not. For example, prosthetic groups and compounds such as NAD, NADP, flavin nucleotides, coenzyme A.
If anyone has time, the {{ Enzyme cofactors}} template would really benefit from your expertise. Thanks! :) Willow 19:11, 27 January 2007 (UTC)
Just FYI, here are examples of articles using the term in the broader sense I indicate in this section:
http://mcb.asm.org/cgi/content/abstract/22/6/1626 http://www.ncbi.nlm.nih.gov/pubmed/15860367 http://www.nature.com/nature/journal/v398/n6730/full/398824a0.html
Jbening ( talk) 00:48, 16 October 2008 (UTC)
I deleted the figure, because I do not what it shows, but I clearly know that succinate dehydrogenase is the typical example of an oxidoreductase that is NOT a heme protein, but an iron suflur protein. This can be verified in any biochemical textbook.
Lulubou ( talk) 09:42, 9 March 2009 (UTC)
Yes, that one looks nice. Lulubou ( talk) 18:35, 9 March 2009 (UTC)
The picture seems to show that succinate and FAD enters during the same reaction cycle. Doesn't FAD enter much earlier and stay for several reactions? Narayanese ( talk) 07:50, 11 March 2009 (UTC)
FAD is covalently bound in succinate dehydrogenase
Lulubou ( talk) 11:38, 11 March 2009 (UTC)
Great !. Good idea to merge the articles on cofactors, coenzymes and prosthetic groups. I have not yet looked at the details, but the article looks great and well structured.
I am just wondering, if those readers that are redirected from the terms ”coenzyme” and ”prosthetic group” mightl not be frustrated when they do not see these terms immediately. Maybe it would be good to add them in the title that could run : Cofactors, coenzymes and prosthetic groups. It would be nice if the terms "coenzymes" and "prosthetic group" already appear in the introduction with a small explanation.
Lulubou ( talk) 11:38, 11 March 2009 (UTC)
This article uses the term thiamine diphosphate (ThDP) and the article to which it links is titled thiamine pyrophosphate (TPP), but acknowledges the alternative term . I know it is a matter of in which enzymology circles you roam, but should we be internally consistent and call it TPP in this cofactors article? The problem I have with thiamine diphosphate is some people (a rather famous enzymologist included) abbreviate it TDP, and that gets confused with the thymidine diphosphate. Pdcook ( talk) 15:38, 9 October 2009 (UTC)
ApoC-II and apoA-I are protein cofactors for lipoprotein lipase (LPL) & lecithin-cholesterol acyltransferase (LCAT), respectively. I just linked the word "cofactor" in that article to this article, but the first thing this article says is contradictory to the function of these two apolipoproteins. What's up? Dcs002 ( talk) 23:24, 18 July 2010 (UTC)
Several glutathione analogs are not yet discussed, including mycothiol, bacillithiol, and trypanothione.
Chlorophyll deserves to be discussed as a cofactor.
The page also should mention that a number of cofactors (e.g. heme) exist in a variety of forms. — Preceding unsigned comment added by Daniel haft ( talk • contribs) 16:09, 19 March 2012 (UTC)
Either one must be false. Please correct. -- 78.50.190.114 ( talk) 16:53, 12 December 2012 (UTC)
The first paragraph states that "A cofactor is a non-protein chemical compound that is bound to a protein..." and the second paragraph states that "Cofactors can be classified depending on how tightly they bind to an enzyme...". These would seem to be in conflict. Are cofactors things that bind to protiens or bind to enzymes or is it both?
The comment(s) below were originally left at Talk:Cofactor (biochemistry)/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.
Changed rating to "high" as this is high school/SAT biology content. - tameeria 21:45, 18 February 2007 (UTC) |
Last edited at 21:45, 18 February 2007 (UTC). Substituted at 11:59, 29 April 2016 (UTC)
Hello fellow Wikipedians,
I have just modified 2 external links on Cofactor (biochemistry). Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:
When you have finished reviewing my changes, you may follow the instructions on the template below to fix any issues with the URLs.
This message was posted before February 2018.
After February 2018, "External links modified" talk page sections are no longer generated or monitored by InternetArchiveBot. No special action is required regarding these talk page notices, other than
regular verification using the archive tool instructions below. Editors
have permission to delete these "External links modified" talk page sections if they want to de-clutter talk pages, but see the
RfC before doing mass systematic removals. This message is updated dynamically through the template {{
source check}}
(last update: 5 June 2024).
Cheers.— InternetArchiveBot ( Report bug) 06:30, 10 August 2017 (UTC)
Hello Boghog,
Currently, Coenzyme is redirected to Cofactor.
I think that Coenzyme should stand by itself. I am willing to re-edit the entries. But, before I start working on this I would like to hear your opinion on the subject.
Rationale, Cofactor entry is currently too long. Coenzyme deserves an entry by itself.
Please inform what you think on this.
Genewiki1 ( talk) 15:28, 11 February 2018 (UTC)
Where do "protein-derived cofactors" fit in the types of cofactors in the introduction? kupirijo ( talk) 13:00, 3 October 2023 (UTC)