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Lead section: build upon the current description to provide an overview of the capping enzyme – structure, common names, its function/activity and impact of its activity while not being too technical. Find reliable and published sources to support the overview; include images of the enzyme and mechanism depictions. Content: Structure, Function (including location and other factors it interacts with), Impact of its activity, See also section (link it to other information sites such as transcription). Images to illustrate its function and interaction with other factors. SabFernMB ( talk) 00:09, 11 March 2014 (UTC) Klbarnhill ( talk) 01:00, 12 March 2014 (UTC)
As this stands it looks very draft-like with many comments about the construction visible. In fact there is as much commenting about what to write as the new writing. So I think this is still a long way from being a B class page. Its probably still start class. I am looking forward to having a bit more material to review. The original lead definition is a better first sentence than the new proposed lead, so I suggest that you merge the content. Some of the new writing is a bit too technical, eg "cotranscriptionally", does this mean "during transcription"?
In Structure is there more to the human capping enzyme than the human guanylyltransferease domain? What kinds of cells produce this, is it all living organisms or just eucaryotes? I there more than one kind? Do mitochondria have them? Who discovered it? What is the effect of malfunction or mutations?
Images have limited types and .fcgi is not one of them. .svg format could be the preference. Before you use an image from a government web site, make sure that it was created by the US government, otherwise it is probably not free to use. Some images would be good here. The image at File:3D cystral structure of human mRNA guanylyltransferase.png is quite replaceable by an image that you have drawn yourself, so use is not fair. So you are going to have to do some more work and locate a free image, or draw one. A protein infobox would be good. Graeme Bartlett ( talk) 10:00, 30 March 2014 (UTC)
A good start!
Hope that this helps -- Catwell99 ( talk) 03:13, 2 April 2014 (UTC)
Hello, I am your fellow classmate Christopher Gerth and was assigned this article for initial review. I think you have a good start on the article. I know all the little things you forget about when trying to get an article started; plus the current article never looks like the final draft of the article you have in your head (unfortunately people can't read minds...Why not ?!). So if you have already noticed these things...my apologies.
1. I think you should move the lead section into the first paragraph of the article and then pear it down. My understanding is that the lead section should let a reader know if there is something in the article they might be interested in. 2. Obviously the references should all be in one section, I am assuming that you know this.
3. The structure for the 3-D enzyme doesn't appear. My guess is that you linked to a file that needs a viewer installed. Try to take a screen shot of the picture on your computer, save as a JPEG (or some suitable file) and then upload that. This will ensure that Wikipedia doesn't have to have the corresponding software installed to view the image (I guess you could review file guidelines).
4. An outlined chemical reaction as equations or pictorially would help the reader to understand the enzyme function more easily.
5. I think there is a template for "enzyme infoboxes" which you can add to your page and would make the page look very academic. In fact, I think this is recommended for enzyme and protein articles.
6. The "see also" section needs to be a bulleted list of articles in Wikipedia with links.
7. I would move the "function" section before the "structure" section, but this is my preference and just a stylistic point.
8. You may want to mention the highly conserved sub-units of the protein as from an evolutionary point this is very interesting.
I like what you've done with this article so far. Here are some suggestions for further development:
You have done some great work with this article. Let me know if you have any questions about the above. Neelix ( talk) 03:08, 14 April 2014 (UTC)
In the lead section, you wrote: “Pre-mRNA undergoes a series of modifications before becoming mature mRNA that exits the nucleus to be translated into functional proteins and capping of the 5' end is the first of these modifications.” You might want to list the other modifications.
As per Wikipedia’s Style Guidelines, you might want to mention mRNA guanylyltransferase in the lead section. It is an alternative name for capping enzyme.
Regarding the Structure section:
Regarding the Function section:
Regarding the Formation of the cap section:
Regarding the Impact of the enzyme's activity section:
The header of the See also section is in the wrong place.
The paragraph about transcription needs its own header. To be honest, I don’t think this paragraph is needed because it seems extraneous. Wikipedia already has an article about transcription.
Remove references that are not cited anywhere in the article (i.e.: the “bulleted” references)
I agree with Deacon C; the Function section should go before the Structure section
Reference 2 should have a doi and/or PMID for easier access
You refer to the capping enzyme as “guanylyltransferase” throughout the article. You might want to refer to it only as “capping enzyme”, so as not to confuse your readers.
S. cerevisiae, CEG1 gene, and CET1 gene should be italicized.
More Wikilinks are needed
Some questions arose in my mind while reading the article:
Overall, the article is progressing nicely. It isn’t written in an overly technical way, which is good. The references you chose were informative, and easily accessible. As far as I can tell, everything is written in your own words. Great job, so far! -- Jocelyn Munson ( talk) 04:12, 14 April 2014 (UTC)
Formation of the cap: It sounds a bit redundant to say that it's a three step process in back to back sentences. I'd rewrite the second sentence to remove that. The images are good, but could use short captions briefly explaining what they're showing. The first image also needs the abbreviations explained; I was able to figure out what they are, but it'd be better to just explicitly state it in a caption. The image of the reactions looks useful, but with no explanation I'm not entirely sure what I'm looking at.
Structure: If possible, any explanation about why a particular structure element is important for a function would be good to add. I italicized CEG1 and CET1; I think that's how you wanted it, but had the wiki formatting wrong.
Impact: Can you explain a little more in-depth about how mutations effect splicing and transcription elongation?
It's good that you're referencing, but I think you're overdoing the inline citations, you don't need to have a citation after every sentence. When you have several sentences that use the same sources, just put the citations at the end of the last sentence. For example, in the impact section, everything is from one source, so just put that citation at the end of the paragraph; it's assumed all the information precluding that citation are from that source. It'll look cleaner and be easier to read without so many in-line citations. The references themselves look good and support the information you're referencing. The reference to our textbook isn't the best choice though; we may have access to it but the general public won't. It looks like you're using to reference somewhat basic knowledge that you could probably find a more easily accessible source for. A few more wikilinks would be good too: splicing in the lead, DNA/RNA ligases, Saccharomyces cerevisiae. The function section looks particularly bare on links. Overall it looks pretty good, keep it up! Lisawisa ( talk) 02:43, 29 April 2014 (UTC)
Overall, the article follows the Style Guidelines. Structure looks good and each section is well developed with neutral tone. Content of this article is detailed and cited correctly.
That being said, I have some comments and suggestions:
Great job so far guys, here are a few suggestions for you as you finish out the semester. Let me know via email or my talk page if you have any questions.
All the best, Keilana| Parlez ici 15:36, 3 May 2014 (UTC)
Hi, @ SabFernMB:, I want to get a check on the licenses of the image files you uploaded to Commons. For example, Bic035i001.jpg -- see c:File_talk:Bic035i001.jpg. That image shows license CC0, but it doesn't match the license of the article, which is CC-BY-NC. Media licensed under non-commercial (NC) licenses are not accepted on commons (might be okay on Wikipedia though -- I'd have to check). Did you contact the author or publisher directly, to get this released under CC0? Klortho ( talk) 02:08, 7 May 2014 (UTC)
The file File:Bic035i003.jpg, used on this page, has been deleted from Wikimedia Commons and re-uploaded at File:Bic035i003.jpg. It should be reviewed to determine if it is compliant with this project's non-free content policy, or else should be deleted and removed from this page. If no action is taken, it will be deleted after 7 days. Commons fair use upload bot ( talk) 06:50, 9 May 2014 (UTC)
![]() | This article is rated C-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | ||||||||||||||||
|
Lead section: build upon the current description to provide an overview of the capping enzyme – structure, common names, its function/activity and impact of its activity while not being too technical. Find reliable and published sources to support the overview; include images of the enzyme and mechanism depictions. Content: Structure, Function (including location and other factors it interacts with), Impact of its activity, See also section (link it to other information sites such as transcription). Images to illustrate its function and interaction with other factors. SabFernMB ( talk) 00:09, 11 March 2014 (UTC) Klbarnhill ( talk) 01:00, 12 March 2014 (UTC)
As this stands it looks very draft-like with many comments about the construction visible. In fact there is as much commenting about what to write as the new writing. So I think this is still a long way from being a B class page. Its probably still start class. I am looking forward to having a bit more material to review. The original lead definition is a better first sentence than the new proposed lead, so I suggest that you merge the content. Some of the new writing is a bit too technical, eg "cotranscriptionally", does this mean "during transcription"?
In Structure is there more to the human capping enzyme than the human guanylyltransferease domain? What kinds of cells produce this, is it all living organisms or just eucaryotes? I there more than one kind? Do mitochondria have them? Who discovered it? What is the effect of malfunction or mutations?
Images have limited types and .fcgi is not one of them. .svg format could be the preference. Before you use an image from a government web site, make sure that it was created by the US government, otherwise it is probably not free to use. Some images would be good here. The image at File:3D cystral structure of human mRNA guanylyltransferase.png is quite replaceable by an image that you have drawn yourself, so use is not fair. So you are going to have to do some more work and locate a free image, or draw one. A protein infobox would be good. Graeme Bartlett ( talk) 10:00, 30 March 2014 (UTC)
A good start!
Hope that this helps -- Catwell99 ( talk) 03:13, 2 April 2014 (UTC)
Hello, I am your fellow classmate Christopher Gerth and was assigned this article for initial review. I think you have a good start on the article. I know all the little things you forget about when trying to get an article started; plus the current article never looks like the final draft of the article you have in your head (unfortunately people can't read minds...Why not ?!). So if you have already noticed these things...my apologies.
1. I think you should move the lead section into the first paragraph of the article and then pear it down. My understanding is that the lead section should let a reader know if there is something in the article they might be interested in. 2. Obviously the references should all be in one section, I am assuming that you know this.
3. The structure for the 3-D enzyme doesn't appear. My guess is that you linked to a file that needs a viewer installed. Try to take a screen shot of the picture on your computer, save as a JPEG (or some suitable file) and then upload that. This will ensure that Wikipedia doesn't have to have the corresponding software installed to view the image (I guess you could review file guidelines).
4. An outlined chemical reaction as equations or pictorially would help the reader to understand the enzyme function more easily.
5. I think there is a template for "enzyme infoboxes" which you can add to your page and would make the page look very academic. In fact, I think this is recommended for enzyme and protein articles.
6. The "see also" section needs to be a bulleted list of articles in Wikipedia with links.
7. I would move the "function" section before the "structure" section, but this is my preference and just a stylistic point.
8. You may want to mention the highly conserved sub-units of the protein as from an evolutionary point this is very interesting.
I like what you've done with this article so far. Here are some suggestions for further development:
You have done some great work with this article. Let me know if you have any questions about the above. Neelix ( talk) 03:08, 14 April 2014 (UTC)
In the lead section, you wrote: “Pre-mRNA undergoes a series of modifications before becoming mature mRNA that exits the nucleus to be translated into functional proteins and capping of the 5' end is the first of these modifications.” You might want to list the other modifications.
As per Wikipedia’s Style Guidelines, you might want to mention mRNA guanylyltransferase in the lead section. It is an alternative name for capping enzyme.
Regarding the Structure section:
Regarding the Function section:
Regarding the Formation of the cap section:
Regarding the Impact of the enzyme's activity section:
The header of the See also section is in the wrong place.
The paragraph about transcription needs its own header. To be honest, I don’t think this paragraph is needed because it seems extraneous. Wikipedia already has an article about transcription.
Remove references that are not cited anywhere in the article (i.e.: the “bulleted” references)
I agree with Deacon C; the Function section should go before the Structure section
Reference 2 should have a doi and/or PMID for easier access
You refer to the capping enzyme as “guanylyltransferase” throughout the article. You might want to refer to it only as “capping enzyme”, so as not to confuse your readers.
S. cerevisiae, CEG1 gene, and CET1 gene should be italicized.
More Wikilinks are needed
Some questions arose in my mind while reading the article:
Overall, the article is progressing nicely. It isn’t written in an overly technical way, which is good. The references you chose were informative, and easily accessible. As far as I can tell, everything is written in your own words. Great job, so far! -- Jocelyn Munson ( talk) 04:12, 14 April 2014 (UTC)
Formation of the cap: It sounds a bit redundant to say that it's a three step process in back to back sentences. I'd rewrite the second sentence to remove that. The images are good, but could use short captions briefly explaining what they're showing. The first image also needs the abbreviations explained; I was able to figure out what they are, but it'd be better to just explicitly state it in a caption. The image of the reactions looks useful, but with no explanation I'm not entirely sure what I'm looking at.
Structure: If possible, any explanation about why a particular structure element is important for a function would be good to add. I italicized CEG1 and CET1; I think that's how you wanted it, but had the wiki formatting wrong.
Impact: Can you explain a little more in-depth about how mutations effect splicing and transcription elongation?
It's good that you're referencing, but I think you're overdoing the inline citations, you don't need to have a citation after every sentence. When you have several sentences that use the same sources, just put the citations at the end of the last sentence. For example, in the impact section, everything is from one source, so just put that citation at the end of the paragraph; it's assumed all the information precluding that citation are from that source. It'll look cleaner and be easier to read without so many in-line citations. The references themselves look good and support the information you're referencing. The reference to our textbook isn't the best choice though; we may have access to it but the general public won't. It looks like you're using to reference somewhat basic knowledge that you could probably find a more easily accessible source for. A few more wikilinks would be good too: splicing in the lead, DNA/RNA ligases, Saccharomyces cerevisiae. The function section looks particularly bare on links. Overall it looks pretty good, keep it up! Lisawisa ( talk) 02:43, 29 April 2014 (UTC)
Overall, the article follows the Style Guidelines. Structure looks good and each section is well developed with neutral tone. Content of this article is detailed and cited correctly.
That being said, I have some comments and suggestions:
Great job so far guys, here are a few suggestions for you as you finish out the semester. Let me know via email or my talk page if you have any questions.
All the best, Keilana| Parlez ici 15:36, 3 May 2014 (UTC)
Hi, @ SabFernMB:, I want to get a check on the licenses of the image files you uploaded to Commons. For example, Bic035i001.jpg -- see c:File_talk:Bic035i001.jpg. That image shows license CC0, but it doesn't match the license of the article, which is CC-BY-NC. Media licensed under non-commercial (NC) licenses are not accepted on commons (might be okay on Wikipedia though -- I'd have to check). Did you contact the author or publisher directly, to get this released under CC0? Klortho ( talk) 02:08, 7 May 2014 (UTC)
The file File:Bic035i003.jpg, used on this page, has been deleted from Wikimedia Commons and re-uploaded at File:Bic035i003.jpg. It should be reviewed to determine if it is compliant with this project's non-free content policy, or else should be deleted and removed from this page. If no action is taken, it will be deleted after 7 days. Commons fair use upload bot ( talk) 06:50, 9 May 2014 (UTC)