From Wikipedia, the free encyclopedia

Image

The image is of the inactive trans isomer. 3,4-dichloro-N-((1R,2R)-2-(dimethylamino)cyclohexyl)-N-methylbenzamide is the active opioid. — Preceding unsigned comment added by 86.30.243.179 ( talk) 09:51, 19 January 2012 (UTC) reply

About time this was checked, some 11 years after this comment! Yes, the (S,S) stereochemistry depicted on PubChem appears to be incorrect. Other sources such as CaymanChem [1] and KEGG [2] as well as literature sources ( doi: 10.1007/s00204-021-03207-9, doi: 10.3390/brainsci10110895) show the (R,R) enantiomer, which makes sense as that matches the stereochemistry of U-47700. Looks like PubChem got this one wrong, I will fix this. Meodipt ( talk) 03:53, 20 September 2023 (UTC) reply

See Also

I can see no chemical similarity between Bromadoline and the drugs in the 'see also' section. I didn't write this page, just added reference, but if nobody has an explaination, I feel that the 'see also' should be removed. — Preceding unsigned comment added by Dvwynn ( talkcontribs) 10:41, 20 May 2014 (UTC) reply

From Wikipedia, the free encyclopedia

Image

The image is of the inactive trans isomer. 3,4-dichloro-N-((1R,2R)-2-(dimethylamino)cyclohexyl)-N-methylbenzamide is the active opioid. — Preceding unsigned comment added by 86.30.243.179 ( talk) 09:51, 19 January 2012 (UTC) reply

About time this was checked, some 11 years after this comment! Yes, the (S,S) stereochemistry depicted on PubChem appears to be incorrect. Other sources such as CaymanChem [1] and KEGG [2] as well as literature sources ( doi: 10.1007/s00204-021-03207-9, doi: 10.3390/brainsci10110895) show the (R,R) enantiomer, which makes sense as that matches the stereochemistry of U-47700. Looks like PubChem got this one wrong, I will fix this. Meodipt ( talk) 03:53, 20 September 2023 (UTC) reply

See Also

I can see no chemical similarity between Bromadoline and the drugs in the 'see also' section. I didn't write this page, just added reference, but if nobody has an explaination, I feel that the 'see also' should be removed. — Preceding unsigned comment added by Dvwynn ( talkcontribs) 10:41, 20 May 2014 (UTC) reply


Videos

Youtube | Vimeo | Bing

Websites

Google | Yahoo | Bing

Encyclopedia

Google | Yahoo | Bing

Facebook