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I'm confused. A stimulant effect is usually a sympathetic effect, increasing heart rate, not a parasympathetic effect. Does anyone more familiar with Arecoline have anything to back up this statement?
According to the book: Medical Pharmacology at a Glance - Fifth Edition (M. J. Neal): Muscarinic effects are mainly parasympathomimetic (except sweating and vasodilation), and in general are the opposite of those caused by sympathetic stimulation. Muscarinic effects include: constriction of the pupil, accomodation for near vision, profuse watery salivation, bronchiolar constriction, bronchosecretion, hypotension, an increase in gastrointestinal motility and secrection contraction of the urinary bladder and sweating.
As I have used arecoline before, I can definitely confirm that it causes "constriction of the pupil", and I also noticed "profuse watery salivation", along with "bronchiolar constriction". The others i'm not sure about as I wasn't really analyzing.
My conclusion is that arecoline is a parasympathomimetic, rather than a sympathomimetic. Mark PEA 22:54, 12 August 2006 (UTC)Mark PEA
Some web sites - such as https://blog.priceplow.com/betel-nut-arecoline and http://www.science20.com/news_articles/betel_nut_addiction_plagues_millions_worldwide_heres_why-158207 and the sites they reference - say this is a carcinogen, or likely carcinogen. Holland jon ( talk) 07:34, 25 October 2015 (UTC)
- [...]
- There is sufficient evidence in humans for the carcinogenicity of betel quid without tobacco. Betel quid without tobacco causes oral cancer.
- There is sufficient evidence in experimental animals for the carcinogenicity of betel quid without tobacco.
- There is sufficient evidence in experimental animals for the carcinogenicity of betel quid with tobacco.
- There is sufficient evidence in experimental animals for the carcinogenicity of areca nut.
- There is sufficient evidence in experimental animals for the carcinogenicity of areca nut with tobacco.
- There is limited evidence in experimental animals for the carcinogenicity of arecoline.
- There is inadequate evidence in experimental animals for the carcinogenicity of arecaidine.
- [...]
References
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This article is rated C-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | |||||||||||
|
Ideal sources for Wikipedia's health content are defined in the guideline
Wikipedia:Identifying reliable sources (medicine) and are typically
review articles. Here are links to possibly useful sources of information about Arecoline.
|
I'm confused. A stimulant effect is usually a sympathetic effect, increasing heart rate, not a parasympathetic effect. Does anyone more familiar with Arecoline have anything to back up this statement?
According to the book: Medical Pharmacology at a Glance - Fifth Edition (M. J. Neal): Muscarinic effects are mainly parasympathomimetic (except sweating and vasodilation), and in general are the opposite of those caused by sympathetic stimulation. Muscarinic effects include: constriction of the pupil, accomodation for near vision, profuse watery salivation, bronchiolar constriction, bronchosecretion, hypotension, an increase in gastrointestinal motility and secrection contraction of the urinary bladder and sweating.
As I have used arecoline before, I can definitely confirm that it causes "constriction of the pupil", and I also noticed "profuse watery salivation", along with "bronchiolar constriction". The others i'm not sure about as I wasn't really analyzing.
My conclusion is that arecoline is a parasympathomimetic, rather than a sympathomimetic. Mark PEA 22:54, 12 August 2006 (UTC)Mark PEA
Some web sites - such as https://blog.priceplow.com/betel-nut-arecoline and http://www.science20.com/news_articles/betel_nut_addiction_plagues_millions_worldwide_heres_why-158207 and the sites they reference - say this is a carcinogen, or likely carcinogen. Holland jon ( talk) 07:34, 25 October 2015 (UTC)
- [...]
- There is sufficient evidence in humans for the carcinogenicity of betel quid without tobacco. Betel quid without tobacco causes oral cancer.
- There is sufficient evidence in experimental animals for the carcinogenicity of betel quid without tobacco.
- There is sufficient evidence in experimental animals for the carcinogenicity of betel quid with tobacco.
- There is sufficient evidence in experimental animals for the carcinogenicity of areca nut.
- There is sufficient evidence in experimental animals for the carcinogenicity of areca nut with tobacco.
- There is limited evidence in experimental animals for the carcinogenicity of arecoline.
- There is inadequate evidence in experimental animals for the carcinogenicity of arecaidine.
- [...]
References
Hello fellow Wikipedians,
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have permission to delete these "External links modified" talk page sections if they want to de-clutter talk pages, but see the
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source check}}
(last update: 18 January 2022).
Cheers.— InternetArchiveBot ( Report bug) 19:57, 8 July 2017 (UTC)