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The reference to Star Scientific should be updated with the information that the FDA is investigating its use of anatabine-containing products. News story: http://washington.cbslocal.com/2013/12/31/fda-says-star-scientific-illegally-marketing-products/ 71.163.117.143 ( talk) 12:59, 1 January 2014 (UTC)
just wanted to leave a quick note here. as per WP:MEDRS we should rely on secondary sources to discuss biological activities and potential drug-like uses for compounds (especially ones in commercial development). I found no reviews discussing anatabine, so i looked at one of the more recent primary sources and created some content based on its discussion section, which provided an overview of work that has been done to date. I removed all the primary sources that were used to directly support content, as it is very suboptimal to use primary sources in the biomedical space (happy to discuss that further if anybody wants to, but pls have a look at an essay i wrote called "Why MEDRS" if you like...it is still drafty.)
With respect to MAO inhibition, I looked at the two sources provided, and neither of them discusses anatabine.
What I found was that the Castagnoli source discusses 2,3,6-trimethyl-1,4-naphthoquinone (TMN) (which looks like this. The Rose article mentions no alkaloids from tobacco other than nicotine. That was surprising, since the article featured MAOi as the most important thing about anatabine. Jytdog ( talk) 21:28, 10 August 2014 (UTC)
The following discussion is closed. Please do not modify it. Subsequent comments should be made on the appropriate discussion page. No further edits should be made to this discussion.
Hello Jytdog!
I saw that you reverted my edit on the anatabine page, so I thought I'd come here to discuss it with you. Since I am a new editor, I am trying to learn from any reverts, so I appreciate your patience and participation. As a reminder, the information in question is below:
In 2013, the company became embroiled in political scandal, when news broke that the governor of Virginia, Bob McDonnell, and his wife had received significant loans and gifts from Jonnie Williams Sr, the CEO of the company. [1] Williams resigned in 2014 and the company changed its name at the same time it changed its board and management, at the end of 2013 due to the scandal. [2]
In your revert of my deletion, you gave the reasoning that "this is very relevant to commercial development of the drug. it belongs in this section." However, I do not understand why a political scandal involving the CEO of a company that happens to make this drug is relevant to the product development of this specific drug. I would understand if the scandal involved the drug itself, such as in the preceding paragraph which talks about the unlawful promotion of the drug, but that is not the case here.
Therefore, could you please explain your rationale for keeping this information in the Anatabine#Commercial Development section in greater detail to me?
References
Thanks! ― Biochemistry🙴❤ 16:53, 13 May 2017 (UTC) (This post was copied here from Jytdog's talk page. ― Biochemistry🙴❤ 17:18, 13 May 2017 (UTC))
- In 2013, the company became embroiled in political scandal when news broke that the governor of Virginia, Bob McDonnell, and his wife had received significant loans and gifts from Jonnie Williams Sr, the CEO of the company, in exchange for promoting Anatabloc. [1] Williams resigned in 2014 and the company changed its name at the same time it changed its board and management, at the end of 2013 due to the scandal. [2]
References
- Former Gov. Bob McDonnell of Virginia and his wife, Maureen, were indicted Tuesday by a federal grand jury on charges of accepting more than $140,000 in loans and gift in exchange for promoting the business of a political patron who was seeking special favors from the state government
- The 14-count indictment filed by the United States attorney for the Eastern District of Virigina included charges of fraud and soliciting loans and gifts from Jonnie R. Williams Sr., the chief executive of Star Scientific, a maker of dietary supplements, who hoped to use the governor to promote his products.
- In 2013, the company became embroiled in political scandal when The New York Times broke that the governor of Virginia, Bob McDonnell, and his wife had received significant loans and gifts from Jonnie Williams Sr, the CEO of Star Scientific, in exchange for promoting its products. [1] Williams resigned in 2014 and the company changed its name at the same time it changed its board and management, at the end of 2013 due to the scandal. [2]
References
"...in exchange for promoting the business of a political patron..."
"...Jonnie R. Williams Sr., a maker of dietary supplements, who hoped to use the governor to promote his products."
"...solicited with the promise that she and the governor could help his company."
"Mr. Williams...sought to use the McDonnells to impress investors, as well as to enlist the governor's support in winning state-funded research on his product."
"...to promote a dietary supplement called Anatabloc, made by Star Scientific."
"'Maureen is excited about the trip to fla to learn more about the products,' he added."
"At the governor's request...policy advisors to meet with Mr. Williams, who was interested in having Virginia's public universities conduct scientific studies of the health benefits of the active ingredient in Anatabloc, which he would be able to point to for investors."
"discussed...having the studies paid for by the State Tobacco Commission."
"...Mr. McDonnell pulled out some Anatabloc from his pocket, said he took it personally and asked the official to 'reach out to the 'Anatabloc people' and meet with them...'"
"Although Mr. McDonnell said he had returned all the gifts, the indictment included a list of property that he and his wife would be required to forfeit if they are convicted. The list includes...30 boxes of Anatabloc."
Now that I look at my work above, it seems to me that greater weight is placed upon the product. If I missed anything, feel free to edit it in above. Let me know if you would disagree with my coding as well, since it is somewhat up to interpretation. What are your thoughts?
P.S. Thank you for continuing this conversation with me! I'm happy to work together on this!― Biochemistry🙴❤ 17:41, 16 May 2017 (UTC)
- In 2013, the company became embroiled in political scandal, when news broke that the governor of Virginia, Bob McDonnell, and his wife had
on the one hand,received significant loans and gifts from Jonnie Williams Sr, the CEO of the Star Scientific,and on the other, were also found to have helped the company in several ways.in exchange for attempting to further the financial interests of the company.
An editor has asked for a discussion to address the redirect /anatabine. Please participate in the redirect discussion if you wish to do so. UnitedStatesian ( talk) 15:01, 10 April 2019 (UTC)
This article is rated Stub-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | |||||||||||
|
Ideal sources for Wikipedia's health content are defined in the guideline
Wikipedia:Identifying reliable sources (medicine) and are typically
review articles. Here are links to possibly useful sources of information about Anatabine.
|
The reference to Star Scientific should be updated with the information that the FDA is investigating its use of anatabine-containing products. News story: http://washington.cbslocal.com/2013/12/31/fda-says-star-scientific-illegally-marketing-products/ 71.163.117.143 ( talk) 12:59, 1 January 2014 (UTC)
just wanted to leave a quick note here. as per WP:MEDRS we should rely on secondary sources to discuss biological activities and potential drug-like uses for compounds (especially ones in commercial development). I found no reviews discussing anatabine, so i looked at one of the more recent primary sources and created some content based on its discussion section, which provided an overview of work that has been done to date. I removed all the primary sources that were used to directly support content, as it is very suboptimal to use primary sources in the biomedical space (happy to discuss that further if anybody wants to, but pls have a look at an essay i wrote called "Why MEDRS" if you like...it is still drafty.)
With respect to MAO inhibition, I looked at the two sources provided, and neither of them discusses anatabine.
What I found was that the Castagnoli source discusses 2,3,6-trimethyl-1,4-naphthoquinone (TMN) (which looks like this. The Rose article mentions no alkaloids from tobacco other than nicotine. That was surprising, since the article featured MAOi as the most important thing about anatabine. Jytdog ( talk) 21:28, 10 August 2014 (UTC)
The following discussion is closed. Please do not modify it. Subsequent comments should be made on the appropriate discussion page. No further edits should be made to this discussion.
Hello Jytdog!
I saw that you reverted my edit on the anatabine page, so I thought I'd come here to discuss it with you. Since I am a new editor, I am trying to learn from any reverts, so I appreciate your patience and participation. As a reminder, the information in question is below:
In 2013, the company became embroiled in political scandal, when news broke that the governor of Virginia, Bob McDonnell, and his wife had received significant loans and gifts from Jonnie Williams Sr, the CEO of the company. [1] Williams resigned in 2014 and the company changed its name at the same time it changed its board and management, at the end of 2013 due to the scandal. [2]
In your revert of my deletion, you gave the reasoning that "this is very relevant to commercial development of the drug. it belongs in this section." However, I do not understand why a political scandal involving the CEO of a company that happens to make this drug is relevant to the product development of this specific drug. I would understand if the scandal involved the drug itself, such as in the preceding paragraph which talks about the unlawful promotion of the drug, but that is not the case here.
Therefore, could you please explain your rationale for keeping this information in the Anatabine#Commercial Development section in greater detail to me?
References
Thanks! ― Biochemistry🙴❤ 16:53, 13 May 2017 (UTC) (This post was copied here from Jytdog's talk page. ― Biochemistry🙴❤ 17:18, 13 May 2017 (UTC))
- In 2013, the company became embroiled in political scandal when news broke that the governor of Virginia, Bob McDonnell, and his wife had received significant loans and gifts from Jonnie Williams Sr, the CEO of the company, in exchange for promoting Anatabloc. [1] Williams resigned in 2014 and the company changed its name at the same time it changed its board and management, at the end of 2013 due to the scandal. [2]
References
- Former Gov. Bob McDonnell of Virginia and his wife, Maureen, were indicted Tuesday by a federal grand jury on charges of accepting more than $140,000 in loans and gift in exchange for promoting the business of a political patron who was seeking special favors from the state government
- The 14-count indictment filed by the United States attorney for the Eastern District of Virigina included charges of fraud and soliciting loans and gifts from Jonnie R. Williams Sr., the chief executive of Star Scientific, a maker of dietary supplements, who hoped to use the governor to promote his products.
- In 2013, the company became embroiled in political scandal when The New York Times broke that the governor of Virginia, Bob McDonnell, and his wife had received significant loans and gifts from Jonnie Williams Sr, the CEO of Star Scientific, in exchange for promoting its products. [1] Williams resigned in 2014 and the company changed its name at the same time it changed its board and management, at the end of 2013 due to the scandal. [2]
References
"...in exchange for promoting the business of a political patron..."
"...Jonnie R. Williams Sr., a maker of dietary supplements, who hoped to use the governor to promote his products."
"...solicited with the promise that she and the governor could help his company."
"Mr. Williams...sought to use the McDonnells to impress investors, as well as to enlist the governor's support in winning state-funded research on his product."
"...to promote a dietary supplement called Anatabloc, made by Star Scientific."
"'Maureen is excited about the trip to fla to learn more about the products,' he added."
"At the governor's request...policy advisors to meet with Mr. Williams, who was interested in having Virginia's public universities conduct scientific studies of the health benefits of the active ingredient in Anatabloc, which he would be able to point to for investors."
"discussed...having the studies paid for by the State Tobacco Commission."
"...Mr. McDonnell pulled out some Anatabloc from his pocket, said he took it personally and asked the official to 'reach out to the 'Anatabloc people' and meet with them...'"
"Although Mr. McDonnell said he had returned all the gifts, the indictment included a list of property that he and his wife would be required to forfeit if they are convicted. The list includes...30 boxes of Anatabloc."
Now that I look at my work above, it seems to me that greater weight is placed upon the product. If I missed anything, feel free to edit it in above. Let me know if you would disagree with my coding as well, since it is somewhat up to interpretation. What are your thoughts?
P.S. Thank you for continuing this conversation with me! I'm happy to work together on this!― Biochemistry🙴❤ 17:41, 16 May 2017 (UTC)
- In 2013, the company became embroiled in political scandal, when news broke that the governor of Virginia, Bob McDonnell, and his wife had
on the one hand,received significant loans and gifts from Jonnie Williams Sr, the CEO of the Star Scientific,and on the other, were also found to have helped the company in several ways.in exchange for attempting to further the financial interests of the company.
An editor has asked for a discussion to address the redirect /anatabine. Please participate in the redirect discussion if you wish to do so. UnitedStatesian ( talk) 15:01, 10 April 2019 (UTC)