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In the recent report, Gulf War Illness and the Health of Gulf War Veterans , page 11, research scientists have indicated that Gulf War veterans developed ALS at twice the rate of nondeployed era veterans. [1] —Preceding unsigned comment added by Thorn breaker ( talk • contribs) 16:27, 24 November 2008 (UTC)
Some text in this article was originally taken from http://www.ninds.nih.gov/disorders/amyotrophiclateralsclerosis/detail_amyotrophiclateralsclerosis.htm (public domain)
Found problem on this page, but when I went to "edit this page" the text looks normal. In the first paragraph, when reading the article (not in edit view) I see "...that control voluntary muscle movement. this disease is a genocide so you need to cut off all relation to the outside world and family. IT WILL KILL YOU. YOU WILL NOT SURVIVE! The disorder causes muscle..." Can someone remove the trollish bits? 70.231.124.107 01:22, 22 January 2007 (UTC) mona
I added a bunch of links. More are needed - i am not a doctor. I only linked those words which seemed most "scientific" to me.-- Amir E. Aharoni 09:14, 8 January 2006 (UTC)
Who's Paul Apisa and why's he under the "famous people" section?—The preceding unsigned comment was added by 129.63.143.58 ( talk • contribs) .
Got one google hit [2]-- JohnDO| Speak your mind 04:26, 27 January 2006 (UTC)
Dude. Seriously. Cut it out. "Famous".-- 86.136.70.62 16:40, 18 February 2006 (UTC)
Hello all, I was just wondering if you were aware of the page motor neuron disease? I've just done quite a big edit over there to try and bring it up to date. Personally I think there shouldn't have to be two seperate articles. In the US, I understand ALS can mean the group of other diseases including ALS, PMA, PLS, and PBP as well as just meaning plain old ALS by itself. We use the term MND in the UK in the same way. If you'd be interested in discussing ways we could integrate please discuss here, on my talk page, or on the MND page.
Thanks -- PaulWicks 23:02, 1 February 2006 (UTC)
seriously peeps i mean it —Preceding unsigned comment added by 24.58.195.170 ( talk) 23:21, 4 October 2007 (UTC)
I thought the article needed a picture so I added one of Lou. If anyone has a better pic feel free to add it... - Ravedave 02:16, 23 February 2006 (UTC)
I find the picture confusing. Both MRI pics have very technical explanations, which are not problematic in themselves; but I think it would be helpful to have some clarification in lay terms and some indication of where in the picture to look. peatswift ( talk) 14:15, 12 April 2012 (UTC)
Hmmm. It is rather technical isn't it? On the PD page we have some classic drawings, perhaps something more like this image ( http://www.mndassociation.org/life_with_mnd/pmapls/what_is_pma.html) which I made, badly, many years ago. -- PaulWicks ( talk) 18:35, 13 April 2012 (UTC)
Added Zeca Afonso to the list. I feel sorry for you guys!!! love ya'll!
I can't seem to edit the article, but American composer Gordon Jenkins also died of ALS. Could someone add him? Bunbrain ( talk) 05:34, 4 December 2008 (UTC)bunbrain
Will do. -- PaulWicks ( talk) 13:43, 4 December 2008 (UTC)
I don't know why this article was created. It only leads to confusion. ALS is a term predominantly used in the USA whilst MND is used elsewhere. Most forms of MND are ALS and so it is a synonym in the USA. Havng this page detracts from the MND page. This page has "notable suffers of ALS" with Stephen Hawking listed and yet as I understand it because of his longevity most neoroligists believe that he has a different form of MND. [3]. As for the other people listed on this page who knows. Jooler 11:00, 25 February 2006 (UTC) - Note this article was 2 January 2006 created from a redirect to MND. Jooler 11:05, 25 February 2006 (UTC)
Jooler whilst I agree with some of your points I doubt our american readers would see it that way, and in fact they might even suggest we ditch MND and switch to ALS as they have the most patients and researchers! Unless you want to put it to a vote of some kind? -- PaulWicks 16:15, 25 February 2006 (UTC)
I think it should stay but you might want to try and edit it so that it is clear that ALS is the type of MND which differentialyl affects the upper and lower motor neurones. But yes Jooler I agree that there will become a split between editors from each side of the Atlantic. TBH I only have time to work on MND not ALS as well as it is, as you say, duplicative and not worth my time justifying my edits to two sets of editors. I'm not convinced by merge, nor delete, but I'd prefere a BOLD edit to make it clearer. The worst that can happen is someone can revert some of them, why not give it a go?-- PaulWicks 14:40, 27 February 2006 (UTC)
Because the articles have been fixed to clarify what is MND and what is ALS and becasue of this link I have removed the merge tag. - Ravedave 04:59, 23 March 2006 (UTC)
"In 90 to 95 % of all ALS cases, the disease occurs apparently at random with no clearly associated risk factors. Patients do not have a family history of the disease, and their family members are not considered to be at increased risk for developing ALS.
About 5 to 10 % of all ALS cases are inherited..."
Where is this from?
Fairly common knowledge amongst professionals, but if you want one try: Hand CK, Rouleau GA. Familial amyotrophic lateral sclerosis. Muscle Nerve 2002;25:135-59.-- PaulWicks 14:37, 27 February 2006 (UTC)
Why is there no metion of Dr. Benjamin Brooks, the UW scientist who discovered Tamoxifen's powers against Als and has discovered equally important drugs that combat ALS?
There's not much mention of individual scientists; for example you might say Bob Brown or Bud Rowland are equally important people in ALS. See labile affect for brief precis of Neurodex.-- PaulWicks 09:26, 7 March 2006 (UTC)
I don't believe Stephen Hawking was ever diagnosed with ALS. He has some form of motor neurone disease, but I've never heard it described as ALS. In fact, he's lived with his condition for 40 years, which would make an ALS diagnosis extremely unlikely. vpoko 18:39 05 Apr 2006
From the MND talk page: Stephen Hawking says in his introduction to "A Brief History of Time" that he has ALS. If he was being non-specific about his dx, as he is British, he would have said he has MND. Therefore he has ALS, albeit the most slowly progressive occurrence known. Cheers --PaulWicks 21:59, 1 February 2006 (UTC)-- PaulWicks 08:55, 6 April 2006 (UTC)
Not in the British print of the book. Please sign your comments. -- PaulWicks 13:16, 12 April 2006 (UTC)
The tragedy here, of course, is that the story of Stephen Hawking gives false hope to every patient newly diagnosed with ALS. None can expect to live even a tenth as long as Hawking has. 75.15.121.220 ( talk) 21:20, 23 June 2008 (UTC)
I belive this whole discussion started because I added a Lou Gehrig picture someone else uploaded, which apparently was a copy-vio, so the next best person I could think of was Mr. Hawking, who's picture I added. If anyone can find a good image of Gehrig we can use, I belive it would be much better. If Hawking does have ALS is is an outlier, so Gehrig would be a better pic.- Ravedave 01:01, 29 April 2006 (UTC)
I think this line of thought occurs frequently in people discussing MND or ALS so I don't think it's attributable entirely to your picture. Also, as Hawking is by far the most recognised person with MND and the only well-known person currently alive with it I think his photo should stay. Perhaps Gehrig's photo in addition would be an improvement though.-- PaulWicks 11:55, 30 April 2006 (UTC)
I just want to hear people stories. My Mother-in-law has ALS and I have been involved with the minnesota ALSA, once I became a wikipedia editor I thought I would try and help improve this page. - Ravedave
Did my PhD in MND on cognitive, emotional, and behavioural changes within sporadic and familial ALS as well as PMA. Also did some brain scanning stuff, tiny bit of epidemiology, and some work on depression. Also I run www.build-uk.net -- PaulWicks 15:19, 28 April 2006 (UTC)
I've been researching ALS for several years after learning of my family history. My grandfather died of ALS, as did his mother. My uncle (7th person in the family to be diagnosed) and mother have both been diagnosed. Based on my mom's diagnosis and genetic testing, I have a 50% chance of having the defect - That's a very strong motivating factor to find out more information. - STG0459 24 October, 2006
My father has been diagnosed, and that even though they told me his kind isn't genetic and I'm not at risk, but it's still important to me to find out more. I just wish I could understand more of what is written here... Computers and Physics stuff I'm golden, even Quantum, but once it turns biological it stops making sense to me. Daropedia ( talk) 01:30, 11 September 2011 (UTC)
The article on Mao Zedong indicates that it is uncertain what, specifically, he had. Both Parkinson's disease and motor neurone disease are mentioned as possibilities. Thus I'm removing him from the list since it isn't clear that he belongs here. -- Zawersh 23:06, 30 April 2006 (UTC)
I don't mean to be offensive, but is it just me, or as time goes on are the people being added as "famous" getting considerably less famous? Is there any kind of guidance on how well-known someone should be? I would have said that Richard Olney the neurologist who is an ALS expert and now has it himself is significantly more famous than a sports coach or musician. However to many outside the field he is probably not considered famous at all! -- PaulWicks 12:42, 23 May 2006 (UTC)
Bump! Anyone else got views on this? -- PaulWicks 09:28, 28 June 2006 (UTC)
I've been googling people who are on the list so far and they've generally been people who can be classified as famous insofar as they achieved national or international recognition in a particular field; such as Viola Tunnard who has a biography on Amazon, or Roy Walford who was in the Biosphere 2 project. My view at present is not to include people who only are famous within a local region or a particularly narrow field, such as someone well known in a single US state. Reason being that if you extend it out far enough this list will become a fairly all-enveloping one; after all ALS is rare but it's not that rare! I'm still flying blind on this one though and would appreciate some input from other editors, even if it's only a "me too" or a "I disagree". Finally, it'd be great if people adding names to this list would consider registering usernames. Cheers, -- PaulWicks 23:35, 1 July 2006 (UTC)
Is there anyone famous from outside the US with this disease?
Please sign your comments. Stephen Hawking is outside the US, as was Jimmy Johnstone and David Niven. However these latter two are probably less widely known internationally. -- PaulWicks 22:34, 29 July 2006 (UTC)
A couple more people have been removed from the list after recent updates. As a general pointer, if the person does not have a wikipedia article written about them, or it is impossible to find any evidence on Google that they exist, or if they can not really be considered as well known outside of a relatively small sphere of influence, they are unlikely to remain on the list. This is not meant to cause offence to people by suggesting their friends or relatives are not "notable people", but Wikipedia is an encyclopedia and to list everyone affected by a disease with ~80,000 patients worldwide would soon become unmanageable. There is an ALS/MND patient registry available online at PatientsLikeMe which has more than 350 names from around the world and will act as a permanent monument to the hundreds of great people who have been afflicted by this terrible illness. Thanks, -- PaulWicks 08:27, 16 September 2006 (UTC)
Jon Stone is credited as the creator of Sesame Street, however the Sesame Street article credits Jim Henson as the creator. Jon Stone's bio page only credits him as a writer and director for Sesame Street.
(Edit)Famous guitarist suffering from ALS: http://en.wikipedia.org/wiki/Jason_Becker —Preceding unsigned comment added by 83.194.135.63 ( talk) 11:27, 5 July 2009 (UTC)
I actually had a business partner who died of ALS many years ago. But for the life of me, I don't understand what the name means. Can someone add an explanation of it to the introductory paragraph? Kaimiddleton 21:57, 17 September 2006 (UTC)
Want to avoid a copyvio but this is a good summary: A-myo-trophic comes from the Greek language. "A" means no or negative. "Myo" refers to muscle, and "Trophic" means nourishment---"No muscle nourishment." When a muscle has no nourishment, it "atrophies" or wastes away. "Lateral" identifies the areas in a person's spinal cord where portions of the nerve cells that signal and control the muscles are located. As this area degenerates it leads to scarring or hardening ("sclerosis") in the region. from http://www.alsa.org/als/what.cfm
Personally I don't think this should be in the lead paragraph but if other authors agree it should be in there somewhere then by all means put it in! -- PaulWicks 17:28, 20 September 2006 (UTC)
I took a bunch of websites that were in the references section and put them into external links because they didn't seem to be serving as citations for specific statements, and because with the footnote style referencing the numbers started over with them and it was confusing (because a statement in the text will have the citation 3, e.g., and there are two 3's in the refs). Of course, if my edit was wrong, you can undo it. But i'd suggest rather than that making everything consistent by putting them all into the footnote format with this template: <ref name=" ">{{cite web | url= | title= | author= | date= | publisher= | accessdate=2006-10-20 }}</ref>. But you can only do that if you have specific sentences for them to reference. Thanks! Peace, delldot | talk 06:47, 2 December 2006 (UTC)
Hey! I'm currently writing a 5-page essay about ALS and spent a lot of time on the page http://www.ninds.nih.gov/disorders/amyotrophiclateralsclerosis/detail_amyotrophiclateralsclerosis.htm before coming on here to see what was written. What I realised was that LARGE parts of this page is just in fact copied off the page I listed above. But no source has been listed!!! Isn't this just plain old plagiarism??? I mean... in the very least the source should be listed.... glad to hear thoughts from you others on this....! Gilraen690 11:43, 13 January 2007 (UTC)Gilraen690
Oh, sorry!!! Gilraen690 18:26, 13 January 2007 (UTC)Gilraen690
I made revisions to the etiology section (formerly known as "Aetiology" and "Causes"). I changed the first two paragraphs to reflect the current scientific opinion that free radical damage does not likely play a major role in pathogenesis. This is based on a number of studies which showed that both active (dismutase-active; retains antioxidant capacity) and inactive forms of mutant SOD1 can cause ALS-like disease in murine models of the disease. Additionally, when tg SOD1 mutant mice also expressed wild-type SOD1 (which functions in a normal antioxidant manner, to the best of current knowledge), no change in disease course was found (even in the case of over-expression). I also adjusted the second paragraph to omit the use of "amyloid-like" as a phrase to describe protein aggregates, as amyloid accumulations are generally considered to be extracellular. Also, I added information about current theories on SOD1 mutant aggregates in disease pathogenesis. JHUbme24 07:09, 24 January 2007 (UTC)JHUbme24
Thankyou, that section needed the attention of a good labrat =) -- PaulWicks 10:48, 24 January 2007 (UTC)
I've flagged where I reckon we need citations re the ALS Association and it disregarding its donors wishes. It reads like these are the words of one of its digruntled donors, and I doubt there is a reputable source that could be quoted on this. Georgethe23rd 14:07, 3 June 2007 (UTC)
There is a review in the latest Lancet that could be useful here: Mitchell JD, Borasio GD (2007). "Amyotrophic lateral sclerosis". Lancet. 369 (9578): 2031–41. doi: 10.1016/S0140-6736(07)60944-1. PMID 17574095.
I am passing through, assessing pages for WPMED. This one looks good enough to get a GA rating. Keep up the good work. -- Una Smith 02:43, 13 July 2007 (UTC)
Have never heard the variant on Guam referred to as an own grupp of ALS, and I have been researcher in this field for years.
Beside the familial forms, you often seperate the bulbar onset ALS from limb onset, because bulbar onset progress more rapid. Further it would perhaps be worth mention ALS with front temporal dementia (FTD) as this is a form that got a lot of attention lately.
A number of areas in the world have increased prevalence of ALS. Guam is not unique. There are Kii in Japan, french west-indies and north Scandinavia. The ALS on Guam have some special features but that has no relevance for people with ALS in the rest of US. —Preceding unsigned comment added by 24.131.239.129 ( talk) 06:30, 24 October 2007 (UTC)
I would agree that a better term for this cluster might be something like "Western Pacific ALS". Guamian ALS is not a diagnostic category as such, and in fact it would make more sense to refer to lytico-bodig. It is still worth mentioning as it is the foundation for some theories as to the causes of ALS. Also please don't consider Wikipedia to be relevant only to US readers!-- PaulWicks 16:32, 24 October 2007 (UTC)
Wikipedia's external links policy and the specific guidelines for medicine-related articles do not permit the inclusion of external links to non-encyclopedic material, particularly including: patient support groups, personal experience/survivor stories, internet chat boards, e-mail discussion groups, recruiters for clinical trials, healthcare providers, fundraisers, or similar pages.
Wikipedia is an encyclopedia, not an advertising opportunity or a support group for patients or their families. Please do not re-insert links that do not conform to the standard rules.
External links are not required in Wikipedia articles. They are permitted in limited numbers and in accordance with the policies linked above. If you want to include one or more external links in this article, please link directly to a webpage that provides detailed, encyclopedic information about the disease. Thanks, WhatamIdoing ( talk) 04:24, 13 April 2008 (UTC)
Hi, He is not dead. He just announced the world he has ALS —Preceding unsigned comment added by 213.156.48.97 ( talk) 15:28, 24 September 2008 (UTC)
Stefano Borgonovo and Piergiorgio Corno are not dead. —Preceding
unsigned comment added by
79.7.153.129 (
talk)
20:13, 8 October 2008 (UTC)
{{
editsemiprotected}}
You have put Stefano Borgonovo in the people who have died from this disease, while he's still alive.
Thanks
DrScarecrows ( talk) 13:58, 9 October 2008 (UTC)
Done, he wasn't mentioned in the cited source for that section anyway, and his Wikipedia article seems to agree with you. Thanks for the correction. ~ mazca t| c 17:12, 9 October 2008 (UTC)
About this change, which de-emphasizes Lou Gehrig (that is, the only reason the typical older American knows about ALS's existence) and adds Stephen Hawking:
Many people, including every neurology expert I've ever heard of, have serious doubts about whether Stephen Hawking actually has ALS. (They typically suggest that he probably has progressive muscular atrophy instead; see this for one example). Hawking has apparently refused to see a neurologist since his initial diagnosis. Do we really want to emphasize him as a "typical" ALS patient? WhatamIdoing ( talk) 00:13, 21 November 2008 (UTC)
I think the statement citing one case of documented lyme disease leading to clinical improvement following treatment is very misleading. If you read the full text of the article (not just the abstract) I am not sure it is even true. The literature is essentially void of such cases outside of this one. There are many dishonest people out there telling people with ALS that they in fact have lyme disease, preying on their desperation to rob them for thousands of dollars for unnecessary treatment --- I wonder if this prompted the inclusion of this article. Please clarify that this one case is a single exception rather than the rule. -- User:74.4.81.27 ( User talk:74.4.81.27)
I wanted to add information on hospice and the US hospice criteria. It has come up several times to me, and it would be helpful to have it added. But this page is semi-protected. How can I become an editor? Jeff Halladay ( talk) 16:42, 3 February 2009 (UTC)
"As a direct result of using all of one's fast" ... all of one's fast???? •Jim62sch• dissera! 21:48, 1 March 2009 (UTC)
I've accessed this page after watching a CBS News Tonight item on it. I've never heard of this variant of motor neurone disease in the UK. Is this term used internationally, or is it just limited to the US? -- 80.176.142.11 ( talk) 23:51, 2 July 2009 (UTC)
The short version is that Motor Neurone Disease (MND) is called ALS in the US.-- PaulWicks ( talk) 22:54, 3 July 2009 (UTC)
it isn't commonly known as Lou Gherig outside the US, so i changed it commonly known as Lou Gherig in North America. Markthemac ( talk) 01:37, 15 July 2009 (UTC)
Is there any way to get english translations for these 2 references (
[4] and
[5] - currently the 7th and 8th references in
this section of the article)?
--
K10wnsta (
talk)
21:25, 20 November 2009 (UTC)
I've removed the claim that "extraordinary" amounts of ceftriaxone can stop ALS. The source is a patent application, which is not a reliable source. Please refer to WP:REDFLAG. Celestra ( talk) 19:47, 1 January 2010 (UTC)
"The patient may ultimately lose the ability to initiate and control all voluntary movement; bladder and bowel sphincters and the muscles responsible for eye movement are usually (but not always) spared." Maybe this should be separated into two sentences because I don't know if only eye movement is spared, or if the bladder, bowel sphincters and eye muscles are spared. 70.171.205.113 ( talk) 02:55, 16 April 2010 (UTC)
Interested in the views of other editors, but IMHO this section is getting far too long, rendering the article difficult to read. One solution to this would be to tag the bios of people with wikipedia articles with the tag affected by MND [6] or died from MND [7]. I suggest rather than make a new one for ALS we use this tag but see if we can change it to say "ALS/MND" perhaps? I would also reduce the number of "well-known" people with ALS from the introductory paragraph. Thoughts? -- PaulWicks ( talk) 12:35, 19 April 2010 (UTC)
NYT reports under
Study Says Brain Trauma Can Mimic A.L.S." that ALS can be diagnosed only by examination of the spinal cord, presumably for the foreseeable future only
post-mortem, and appears to be drastically over-diagnosed, at least among those subject to repeated head trauma.
Lou Gehrig's long history of head-trauma sports and "Iron Horse" rep for playing hurt will, IMO, make him the presumptive poster-child for the misdiagnosis, if not for playing hurt.
My impulse was to start editing, but instead i'm going to see first if anyone else is having the same impulse, here or at
Talk:Lou Gehrig.
Edit conflicts are such a drag!
--
Jerzy•
t
21:59, 18 August 2010 (UTC)
A documentary segment on ALS and sports on "Real Sports with Bryant Gumbel" (HBO Sports), shown on TV today, presents evidence that sports figures (including Lou Gehrig) who had many head injuries (Gehrig had fractures, loss of consciousness; many football players, as compared to the general population, have also died or are currently suffering with a diagnosis of ALS.
At one point, they admit that "it looks like ALS, so for the public it is ALS," so it seems likely that ALS (which may be caused mostly by a genetic fault) is a different disease with similar symptoms than this ALS-like disease experienced by athletes with repeated head traumata. The article already mentions this in one place. I feel sure that the distinction between these two diseases will be made clearly, yes, for the public, who are more intelligent that some media seem to believe. It may even turn out that hereditary ALS is the same disease (that is, that all ALS patients had head traumata in their history), although that's not very likely.
An article on this newly-recognized topic is about to be published in that neurophysiology journal. [1] I imagine it can be argued that a peer-reviewed article is a reliable source for medical news. Certainly such articles are widely used on WP without complaint. Or we can wait until The National Enquirer reports on the article, granting it the officially acceptable status of secondary reference.
David Spector (talk) 00:26, 25 August 2010 (UTC)
One user has vandalized multiple times on this page. I reverted back to the original but he did multiple changes so can someone please just double check that it was all removed. I am still semi-new to reverting back pages when there is lots of changes. Thanks! JimmyOrangeSeed ( talk) 19:30, 17 February 2011 (UTC)
I've just expanded the introductory section by giving a clinical insight about the main features and prognosis of the disease. Please contribute to it as much as possible. RaspberryKlonopin ( talk) 04:24, 5 April 2011 (UTC)
Wondering where the reference to a gold toilet as a cure came from. Seems a little out there to not have a reference?? Thanks Gatorsgirl ( talk) 18:13, 6 April 2011 (UTC)
Is there now a TOW policy against that? Celebs like hawking (who I believe is the longest living survivor) seem worthy of mention An in pop culture section seems appropriate too. (ip's shouldn't have to sign their posts and display their IP's so readily- I am only doing so because otherwise a bot will come in and do it for me)-- 68.225.194.245 ( talk) 01:11, 15 June 2011 (UTC)
This is interesting, can the information be added to the article? http://neurosciencenews.com/als-research-discovery-lou-gehrigs-disease-common-cause-found/ — Preceding unsigned comment added by 96.24.76.176 ( talk) 20:26, 23 October 2011 (UTC)
I noticed that there is no mention of Stephen Hawking at all in the article now. I wanted to bring this up for discussion here before adding it so that a) I wasn't being unilateral and b) that this information was added in the best possible way and in the right spot.
I went through the archives and saw the rice and fall of the list of famous people with ALS, and I think doing lists of famous people who have X is a slippery slope. I also saw the person who brought up the possibility that Stephen Hawking might not have ALS but he or she had absolutely nothing to back that up (a mention in a news section summary isn't really a good source) versus plenty of useable sources that cite him having ALS, including his books although I question whether using him for a source on a condition he has is useable. One way or another at least a one or two sentence reference to him should be added for completeness reasons since he is considered the most famous person living with the disease and the article appears incomplete without it and I would expect many readers would expect it. Cat-five - talk 03:53, 31 October 2011 (UTC)
Olney, a pioneer in clinical research on ALS, just died. Would he be worth mentioning somewhere in this article? 4meter4 ( talk) 19:31, 5 February 2012 (UTC)
Not sure if this warrants a mention in the main article yet but some 24+ ALS patients are using sodium chlorite to try to improve their symptoms. ( Medical Mavericks) - Rod57 ( talk) 10:57, 6 July 2012 (UTC)
User:Yannako recently added the following sentence to "Signs and symptoms" section: "Tongue fasciculations are highly specific for ALS. [1]". As tongue fasciculations occur in other neuromuscular disorders as well (e.g., they are a fairly common symptom in spinal muscular atrophy), I temporarily removed this sentence to here so it can be discussed. Just to be clear, I am no expert in ALS but have a fair knowledge of spinal muscular atrophies; hence my reaction. Thanks to share your thoughts. kashmiri 16:49, 10 October 2012 (UTC)
An unproportionately lengthy section titled "Head injuries as a cause of ALS" was added today by User:Eric.laporta. Its text IMHO somewhat lacks on encyclopaedic style and is poorly referenced (mainly to primary sources and newspapers, otherwise WP:OR). As such in my opinion it cannot go into the article. I am moving it here before blanking the section so that it can be worked on if anyone is interested.
PMND
was invoked but never defined (see the
help page).Biography
was invoked but never defined (see the
help page).{{
cite journal}}
: Cite journal requires |journal=
(
help); Text "Journal of the Neurological Sciences" ignored (
help)
This is an archive of past discussions. Do not edit the contents of this page. If you wish to start a new discussion or revive an old one, please do so on the current talk page. |
Archive 1 | Archive 2 | Archive 3 |
In the recent report, Gulf War Illness and the Health of Gulf War Veterans , page 11, research scientists have indicated that Gulf War veterans developed ALS at twice the rate of nondeployed era veterans. [1] —Preceding unsigned comment added by Thorn breaker ( talk • contribs) 16:27, 24 November 2008 (UTC)
Some text in this article was originally taken from http://www.ninds.nih.gov/disorders/amyotrophiclateralsclerosis/detail_amyotrophiclateralsclerosis.htm (public domain)
Found problem on this page, but when I went to "edit this page" the text looks normal. In the first paragraph, when reading the article (not in edit view) I see "...that control voluntary muscle movement. this disease is a genocide so you need to cut off all relation to the outside world and family. IT WILL KILL YOU. YOU WILL NOT SURVIVE! The disorder causes muscle..." Can someone remove the trollish bits? 70.231.124.107 01:22, 22 January 2007 (UTC) mona
I added a bunch of links. More are needed - i am not a doctor. I only linked those words which seemed most "scientific" to me.-- Amir E. Aharoni 09:14, 8 January 2006 (UTC)
Who's Paul Apisa and why's he under the "famous people" section?—The preceding unsigned comment was added by 129.63.143.58 ( talk • contribs) .
Got one google hit [2]-- JohnDO| Speak your mind 04:26, 27 January 2006 (UTC)
Dude. Seriously. Cut it out. "Famous".-- 86.136.70.62 16:40, 18 February 2006 (UTC)
Hello all, I was just wondering if you were aware of the page motor neuron disease? I've just done quite a big edit over there to try and bring it up to date. Personally I think there shouldn't have to be two seperate articles. In the US, I understand ALS can mean the group of other diseases including ALS, PMA, PLS, and PBP as well as just meaning plain old ALS by itself. We use the term MND in the UK in the same way. If you'd be interested in discussing ways we could integrate please discuss here, on my talk page, or on the MND page.
Thanks -- PaulWicks 23:02, 1 February 2006 (UTC)
seriously peeps i mean it —Preceding unsigned comment added by 24.58.195.170 ( talk) 23:21, 4 October 2007 (UTC)
I thought the article needed a picture so I added one of Lou. If anyone has a better pic feel free to add it... - Ravedave 02:16, 23 February 2006 (UTC)
I find the picture confusing. Both MRI pics have very technical explanations, which are not problematic in themselves; but I think it would be helpful to have some clarification in lay terms and some indication of where in the picture to look. peatswift ( talk) 14:15, 12 April 2012 (UTC)
Hmmm. It is rather technical isn't it? On the PD page we have some classic drawings, perhaps something more like this image ( http://www.mndassociation.org/life_with_mnd/pmapls/what_is_pma.html) which I made, badly, many years ago. -- PaulWicks ( talk) 18:35, 13 April 2012 (UTC)
Added Zeca Afonso to the list. I feel sorry for you guys!!! love ya'll!
I can't seem to edit the article, but American composer Gordon Jenkins also died of ALS. Could someone add him? Bunbrain ( talk) 05:34, 4 December 2008 (UTC)bunbrain
Will do. -- PaulWicks ( talk) 13:43, 4 December 2008 (UTC)
I don't know why this article was created. It only leads to confusion. ALS is a term predominantly used in the USA whilst MND is used elsewhere. Most forms of MND are ALS and so it is a synonym in the USA. Havng this page detracts from the MND page. This page has "notable suffers of ALS" with Stephen Hawking listed and yet as I understand it because of his longevity most neoroligists believe that he has a different form of MND. [3]. As for the other people listed on this page who knows. Jooler 11:00, 25 February 2006 (UTC) - Note this article was 2 January 2006 created from a redirect to MND. Jooler 11:05, 25 February 2006 (UTC)
Jooler whilst I agree with some of your points I doubt our american readers would see it that way, and in fact they might even suggest we ditch MND and switch to ALS as they have the most patients and researchers! Unless you want to put it to a vote of some kind? -- PaulWicks 16:15, 25 February 2006 (UTC)
I think it should stay but you might want to try and edit it so that it is clear that ALS is the type of MND which differentialyl affects the upper and lower motor neurones. But yes Jooler I agree that there will become a split between editors from each side of the Atlantic. TBH I only have time to work on MND not ALS as well as it is, as you say, duplicative and not worth my time justifying my edits to two sets of editors. I'm not convinced by merge, nor delete, but I'd prefere a BOLD edit to make it clearer. The worst that can happen is someone can revert some of them, why not give it a go?-- PaulWicks 14:40, 27 February 2006 (UTC)
Because the articles have been fixed to clarify what is MND and what is ALS and becasue of this link I have removed the merge tag. - Ravedave 04:59, 23 March 2006 (UTC)
"In 90 to 95 % of all ALS cases, the disease occurs apparently at random with no clearly associated risk factors. Patients do not have a family history of the disease, and their family members are not considered to be at increased risk for developing ALS.
About 5 to 10 % of all ALS cases are inherited..."
Where is this from?
Fairly common knowledge amongst professionals, but if you want one try: Hand CK, Rouleau GA. Familial amyotrophic lateral sclerosis. Muscle Nerve 2002;25:135-59.-- PaulWicks 14:37, 27 February 2006 (UTC)
Why is there no metion of Dr. Benjamin Brooks, the UW scientist who discovered Tamoxifen's powers against Als and has discovered equally important drugs that combat ALS?
There's not much mention of individual scientists; for example you might say Bob Brown or Bud Rowland are equally important people in ALS. See labile affect for brief precis of Neurodex.-- PaulWicks 09:26, 7 March 2006 (UTC)
I don't believe Stephen Hawking was ever diagnosed with ALS. He has some form of motor neurone disease, but I've never heard it described as ALS. In fact, he's lived with his condition for 40 years, which would make an ALS diagnosis extremely unlikely. vpoko 18:39 05 Apr 2006
From the MND talk page: Stephen Hawking says in his introduction to "A Brief History of Time" that he has ALS. If he was being non-specific about his dx, as he is British, he would have said he has MND. Therefore he has ALS, albeit the most slowly progressive occurrence known. Cheers --PaulWicks 21:59, 1 February 2006 (UTC)-- PaulWicks 08:55, 6 April 2006 (UTC)
Not in the British print of the book. Please sign your comments. -- PaulWicks 13:16, 12 April 2006 (UTC)
The tragedy here, of course, is that the story of Stephen Hawking gives false hope to every patient newly diagnosed with ALS. None can expect to live even a tenth as long as Hawking has. 75.15.121.220 ( talk) 21:20, 23 June 2008 (UTC)
I belive this whole discussion started because I added a Lou Gehrig picture someone else uploaded, which apparently was a copy-vio, so the next best person I could think of was Mr. Hawking, who's picture I added. If anyone can find a good image of Gehrig we can use, I belive it would be much better. If Hawking does have ALS is is an outlier, so Gehrig would be a better pic.- Ravedave 01:01, 29 April 2006 (UTC)
I think this line of thought occurs frequently in people discussing MND or ALS so I don't think it's attributable entirely to your picture. Also, as Hawking is by far the most recognised person with MND and the only well-known person currently alive with it I think his photo should stay. Perhaps Gehrig's photo in addition would be an improvement though.-- PaulWicks 11:55, 30 April 2006 (UTC)
I just want to hear people stories. My Mother-in-law has ALS and I have been involved with the minnesota ALSA, once I became a wikipedia editor I thought I would try and help improve this page. - Ravedave
Did my PhD in MND on cognitive, emotional, and behavioural changes within sporadic and familial ALS as well as PMA. Also did some brain scanning stuff, tiny bit of epidemiology, and some work on depression. Also I run www.build-uk.net -- PaulWicks 15:19, 28 April 2006 (UTC)
I've been researching ALS for several years after learning of my family history. My grandfather died of ALS, as did his mother. My uncle (7th person in the family to be diagnosed) and mother have both been diagnosed. Based on my mom's diagnosis and genetic testing, I have a 50% chance of having the defect - That's a very strong motivating factor to find out more information. - STG0459 24 October, 2006
My father has been diagnosed, and that even though they told me his kind isn't genetic and I'm not at risk, but it's still important to me to find out more. I just wish I could understand more of what is written here... Computers and Physics stuff I'm golden, even Quantum, but once it turns biological it stops making sense to me. Daropedia ( talk) 01:30, 11 September 2011 (UTC)
The article on Mao Zedong indicates that it is uncertain what, specifically, he had. Both Parkinson's disease and motor neurone disease are mentioned as possibilities. Thus I'm removing him from the list since it isn't clear that he belongs here. -- Zawersh 23:06, 30 April 2006 (UTC)
I don't mean to be offensive, but is it just me, or as time goes on are the people being added as "famous" getting considerably less famous? Is there any kind of guidance on how well-known someone should be? I would have said that Richard Olney the neurologist who is an ALS expert and now has it himself is significantly more famous than a sports coach or musician. However to many outside the field he is probably not considered famous at all! -- PaulWicks 12:42, 23 May 2006 (UTC)
Bump! Anyone else got views on this? -- PaulWicks 09:28, 28 June 2006 (UTC)
I've been googling people who are on the list so far and they've generally been people who can be classified as famous insofar as they achieved national or international recognition in a particular field; such as Viola Tunnard who has a biography on Amazon, or Roy Walford who was in the Biosphere 2 project. My view at present is not to include people who only are famous within a local region or a particularly narrow field, such as someone well known in a single US state. Reason being that if you extend it out far enough this list will become a fairly all-enveloping one; after all ALS is rare but it's not that rare! I'm still flying blind on this one though and would appreciate some input from other editors, even if it's only a "me too" or a "I disagree". Finally, it'd be great if people adding names to this list would consider registering usernames. Cheers, -- PaulWicks 23:35, 1 July 2006 (UTC)
Is there anyone famous from outside the US with this disease?
Please sign your comments. Stephen Hawking is outside the US, as was Jimmy Johnstone and David Niven. However these latter two are probably less widely known internationally. -- PaulWicks 22:34, 29 July 2006 (UTC)
A couple more people have been removed from the list after recent updates. As a general pointer, if the person does not have a wikipedia article written about them, or it is impossible to find any evidence on Google that they exist, or if they can not really be considered as well known outside of a relatively small sphere of influence, they are unlikely to remain on the list. This is not meant to cause offence to people by suggesting their friends or relatives are not "notable people", but Wikipedia is an encyclopedia and to list everyone affected by a disease with ~80,000 patients worldwide would soon become unmanageable. There is an ALS/MND patient registry available online at PatientsLikeMe which has more than 350 names from around the world and will act as a permanent monument to the hundreds of great people who have been afflicted by this terrible illness. Thanks, -- PaulWicks 08:27, 16 September 2006 (UTC)
Jon Stone is credited as the creator of Sesame Street, however the Sesame Street article credits Jim Henson as the creator. Jon Stone's bio page only credits him as a writer and director for Sesame Street.
(Edit)Famous guitarist suffering from ALS: http://en.wikipedia.org/wiki/Jason_Becker —Preceding unsigned comment added by 83.194.135.63 ( talk) 11:27, 5 July 2009 (UTC)
I actually had a business partner who died of ALS many years ago. But for the life of me, I don't understand what the name means. Can someone add an explanation of it to the introductory paragraph? Kaimiddleton 21:57, 17 September 2006 (UTC)
Want to avoid a copyvio but this is a good summary: A-myo-trophic comes from the Greek language. "A" means no or negative. "Myo" refers to muscle, and "Trophic" means nourishment---"No muscle nourishment." When a muscle has no nourishment, it "atrophies" or wastes away. "Lateral" identifies the areas in a person's spinal cord where portions of the nerve cells that signal and control the muscles are located. As this area degenerates it leads to scarring or hardening ("sclerosis") in the region. from http://www.alsa.org/als/what.cfm
Personally I don't think this should be in the lead paragraph but if other authors agree it should be in there somewhere then by all means put it in! -- PaulWicks 17:28, 20 September 2006 (UTC)
I took a bunch of websites that were in the references section and put them into external links because they didn't seem to be serving as citations for specific statements, and because with the footnote style referencing the numbers started over with them and it was confusing (because a statement in the text will have the citation 3, e.g., and there are two 3's in the refs). Of course, if my edit was wrong, you can undo it. But i'd suggest rather than that making everything consistent by putting them all into the footnote format with this template: <ref name=" ">{{cite web | url= | title= | author= | date= | publisher= | accessdate=2006-10-20 }}</ref>. But you can only do that if you have specific sentences for them to reference. Thanks! Peace, delldot | talk 06:47, 2 December 2006 (UTC)
Hey! I'm currently writing a 5-page essay about ALS and spent a lot of time on the page http://www.ninds.nih.gov/disorders/amyotrophiclateralsclerosis/detail_amyotrophiclateralsclerosis.htm before coming on here to see what was written. What I realised was that LARGE parts of this page is just in fact copied off the page I listed above. But no source has been listed!!! Isn't this just plain old plagiarism??? I mean... in the very least the source should be listed.... glad to hear thoughts from you others on this....! Gilraen690 11:43, 13 January 2007 (UTC)Gilraen690
Oh, sorry!!! Gilraen690 18:26, 13 January 2007 (UTC)Gilraen690
I made revisions to the etiology section (formerly known as "Aetiology" and "Causes"). I changed the first two paragraphs to reflect the current scientific opinion that free radical damage does not likely play a major role in pathogenesis. This is based on a number of studies which showed that both active (dismutase-active; retains antioxidant capacity) and inactive forms of mutant SOD1 can cause ALS-like disease in murine models of the disease. Additionally, when tg SOD1 mutant mice also expressed wild-type SOD1 (which functions in a normal antioxidant manner, to the best of current knowledge), no change in disease course was found (even in the case of over-expression). I also adjusted the second paragraph to omit the use of "amyloid-like" as a phrase to describe protein aggregates, as amyloid accumulations are generally considered to be extracellular. Also, I added information about current theories on SOD1 mutant aggregates in disease pathogenesis. JHUbme24 07:09, 24 January 2007 (UTC)JHUbme24
Thankyou, that section needed the attention of a good labrat =) -- PaulWicks 10:48, 24 January 2007 (UTC)
I've flagged where I reckon we need citations re the ALS Association and it disregarding its donors wishes. It reads like these are the words of one of its digruntled donors, and I doubt there is a reputable source that could be quoted on this. Georgethe23rd 14:07, 3 June 2007 (UTC)
There is a review in the latest Lancet that could be useful here: Mitchell JD, Borasio GD (2007). "Amyotrophic lateral sclerosis". Lancet. 369 (9578): 2031–41. doi: 10.1016/S0140-6736(07)60944-1. PMID 17574095.
I am passing through, assessing pages for WPMED. This one looks good enough to get a GA rating. Keep up the good work. -- Una Smith 02:43, 13 July 2007 (UTC)
Have never heard the variant on Guam referred to as an own grupp of ALS, and I have been researcher in this field for years.
Beside the familial forms, you often seperate the bulbar onset ALS from limb onset, because bulbar onset progress more rapid. Further it would perhaps be worth mention ALS with front temporal dementia (FTD) as this is a form that got a lot of attention lately.
A number of areas in the world have increased prevalence of ALS. Guam is not unique. There are Kii in Japan, french west-indies and north Scandinavia. The ALS on Guam have some special features but that has no relevance for people with ALS in the rest of US. —Preceding unsigned comment added by 24.131.239.129 ( talk) 06:30, 24 October 2007 (UTC)
I would agree that a better term for this cluster might be something like "Western Pacific ALS". Guamian ALS is not a diagnostic category as such, and in fact it would make more sense to refer to lytico-bodig. It is still worth mentioning as it is the foundation for some theories as to the causes of ALS. Also please don't consider Wikipedia to be relevant only to US readers!-- PaulWicks 16:32, 24 October 2007 (UTC)
Wikipedia's external links policy and the specific guidelines for medicine-related articles do not permit the inclusion of external links to non-encyclopedic material, particularly including: patient support groups, personal experience/survivor stories, internet chat boards, e-mail discussion groups, recruiters for clinical trials, healthcare providers, fundraisers, or similar pages.
Wikipedia is an encyclopedia, not an advertising opportunity or a support group for patients or their families. Please do not re-insert links that do not conform to the standard rules.
External links are not required in Wikipedia articles. They are permitted in limited numbers and in accordance with the policies linked above. If you want to include one or more external links in this article, please link directly to a webpage that provides detailed, encyclopedic information about the disease. Thanks, WhatamIdoing ( talk) 04:24, 13 April 2008 (UTC)
Hi, He is not dead. He just announced the world he has ALS —Preceding unsigned comment added by 213.156.48.97 ( talk) 15:28, 24 September 2008 (UTC)
Stefano Borgonovo and Piergiorgio Corno are not dead. —Preceding
unsigned comment added by
79.7.153.129 (
talk)
20:13, 8 October 2008 (UTC)
{{
editsemiprotected}}
You have put Stefano Borgonovo in the people who have died from this disease, while he's still alive.
Thanks
DrScarecrows ( talk) 13:58, 9 October 2008 (UTC)
Done, he wasn't mentioned in the cited source for that section anyway, and his Wikipedia article seems to agree with you. Thanks for the correction. ~ mazca t| c 17:12, 9 October 2008 (UTC)
About this change, which de-emphasizes Lou Gehrig (that is, the only reason the typical older American knows about ALS's existence) and adds Stephen Hawking:
Many people, including every neurology expert I've ever heard of, have serious doubts about whether Stephen Hawking actually has ALS. (They typically suggest that he probably has progressive muscular atrophy instead; see this for one example). Hawking has apparently refused to see a neurologist since his initial diagnosis. Do we really want to emphasize him as a "typical" ALS patient? WhatamIdoing ( talk) 00:13, 21 November 2008 (UTC)
I think the statement citing one case of documented lyme disease leading to clinical improvement following treatment is very misleading. If you read the full text of the article (not just the abstract) I am not sure it is even true. The literature is essentially void of such cases outside of this one. There are many dishonest people out there telling people with ALS that they in fact have lyme disease, preying on their desperation to rob them for thousands of dollars for unnecessary treatment --- I wonder if this prompted the inclusion of this article. Please clarify that this one case is a single exception rather than the rule. -- User:74.4.81.27 ( User talk:74.4.81.27)
I wanted to add information on hospice and the US hospice criteria. It has come up several times to me, and it would be helpful to have it added. But this page is semi-protected. How can I become an editor? Jeff Halladay ( talk) 16:42, 3 February 2009 (UTC)
"As a direct result of using all of one's fast" ... all of one's fast???? •Jim62sch• dissera! 21:48, 1 March 2009 (UTC)
I've accessed this page after watching a CBS News Tonight item on it. I've never heard of this variant of motor neurone disease in the UK. Is this term used internationally, or is it just limited to the US? -- 80.176.142.11 ( talk) 23:51, 2 July 2009 (UTC)
The short version is that Motor Neurone Disease (MND) is called ALS in the US.-- PaulWicks ( talk) 22:54, 3 July 2009 (UTC)
it isn't commonly known as Lou Gherig outside the US, so i changed it commonly known as Lou Gherig in North America. Markthemac ( talk) 01:37, 15 July 2009 (UTC)
Is there any way to get english translations for these 2 references (
[4] and
[5] - currently the 7th and 8th references in
this section of the article)?
--
K10wnsta (
talk)
21:25, 20 November 2009 (UTC)
I've removed the claim that "extraordinary" amounts of ceftriaxone can stop ALS. The source is a patent application, which is not a reliable source. Please refer to WP:REDFLAG. Celestra ( talk) 19:47, 1 January 2010 (UTC)
"The patient may ultimately lose the ability to initiate and control all voluntary movement; bladder and bowel sphincters and the muscles responsible for eye movement are usually (but not always) spared." Maybe this should be separated into two sentences because I don't know if only eye movement is spared, or if the bladder, bowel sphincters and eye muscles are spared. 70.171.205.113 ( talk) 02:55, 16 April 2010 (UTC)
Interested in the views of other editors, but IMHO this section is getting far too long, rendering the article difficult to read. One solution to this would be to tag the bios of people with wikipedia articles with the tag affected by MND [6] or died from MND [7]. I suggest rather than make a new one for ALS we use this tag but see if we can change it to say "ALS/MND" perhaps? I would also reduce the number of "well-known" people with ALS from the introductory paragraph. Thoughts? -- PaulWicks ( talk) 12:35, 19 April 2010 (UTC)
NYT reports under
Study Says Brain Trauma Can Mimic A.L.S." that ALS can be diagnosed only by examination of the spinal cord, presumably for the foreseeable future only
post-mortem, and appears to be drastically over-diagnosed, at least among those subject to repeated head trauma.
Lou Gehrig's long history of head-trauma sports and "Iron Horse" rep for playing hurt will, IMO, make him the presumptive poster-child for the misdiagnosis, if not for playing hurt.
My impulse was to start editing, but instead i'm going to see first if anyone else is having the same impulse, here or at
Talk:Lou Gehrig.
Edit conflicts are such a drag!
--
Jerzy•
t
21:59, 18 August 2010 (UTC)
A documentary segment on ALS and sports on "Real Sports with Bryant Gumbel" (HBO Sports), shown on TV today, presents evidence that sports figures (including Lou Gehrig) who had many head injuries (Gehrig had fractures, loss of consciousness; many football players, as compared to the general population, have also died or are currently suffering with a diagnosis of ALS.
At one point, they admit that "it looks like ALS, so for the public it is ALS," so it seems likely that ALS (which may be caused mostly by a genetic fault) is a different disease with similar symptoms than this ALS-like disease experienced by athletes with repeated head traumata. The article already mentions this in one place. I feel sure that the distinction between these two diseases will be made clearly, yes, for the public, who are more intelligent that some media seem to believe. It may even turn out that hereditary ALS is the same disease (that is, that all ALS patients had head traumata in their history), although that's not very likely.
An article on this newly-recognized topic is about to be published in that neurophysiology journal. [1] I imagine it can be argued that a peer-reviewed article is a reliable source for medical news. Certainly such articles are widely used on WP without complaint. Or we can wait until The National Enquirer reports on the article, granting it the officially acceptable status of secondary reference.
David Spector (talk) 00:26, 25 August 2010 (UTC)
One user has vandalized multiple times on this page. I reverted back to the original but he did multiple changes so can someone please just double check that it was all removed. I am still semi-new to reverting back pages when there is lots of changes. Thanks! JimmyOrangeSeed ( talk) 19:30, 17 February 2011 (UTC)
I've just expanded the introductory section by giving a clinical insight about the main features and prognosis of the disease. Please contribute to it as much as possible. RaspberryKlonopin ( talk) 04:24, 5 April 2011 (UTC)
Wondering where the reference to a gold toilet as a cure came from. Seems a little out there to not have a reference?? Thanks Gatorsgirl ( talk) 18:13, 6 April 2011 (UTC)
Is there now a TOW policy against that? Celebs like hawking (who I believe is the longest living survivor) seem worthy of mention An in pop culture section seems appropriate too. (ip's shouldn't have to sign their posts and display their IP's so readily- I am only doing so because otherwise a bot will come in and do it for me)-- 68.225.194.245 ( talk) 01:11, 15 June 2011 (UTC)
This is interesting, can the information be added to the article? http://neurosciencenews.com/als-research-discovery-lou-gehrigs-disease-common-cause-found/ — Preceding unsigned comment added by 96.24.76.176 ( talk) 20:26, 23 October 2011 (UTC)
I noticed that there is no mention of Stephen Hawking at all in the article now. I wanted to bring this up for discussion here before adding it so that a) I wasn't being unilateral and b) that this information was added in the best possible way and in the right spot.
I went through the archives and saw the rice and fall of the list of famous people with ALS, and I think doing lists of famous people who have X is a slippery slope. I also saw the person who brought up the possibility that Stephen Hawking might not have ALS but he or she had absolutely nothing to back that up (a mention in a news section summary isn't really a good source) versus plenty of useable sources that cite him having ALS, including his books although I question whether using him for a source on a condition he has is useable. One way or another at least a one or two sentence reference to him should be added for completeness reasons since he is considered the most famous person living with the disease and the article appears incomplete without it and I would expect many readers would expect it. Cat-five - talk 03:53, 31 October 2011 (UTC)
Olney, a pioneer in clinical research on ALS, just died. Would he be worth mentioning somewhere in this article? 4meter4 ( talk) 19:31, 5 February 2012 (UTC)
Not sure if this warrants a mention in the main article yet but some 24+ ALS patients are using sodium chlorite to try to improve their symptoms. ( Medical Mavericks) - Rod57 ( talk) 10:57, 6 July 2012 (UTC)
User:Yannako recently added the following sentence to "Signs and symptoms" section: "Tongue fasciculations are highly specific for ALS. [1]". As tongue fasciculations occur in other neuromuscular disorders as well (e.g., they are a fairly common symptom in spinal muscular atrophy), I temporarily removed this sentence to here so it can be discussed. Just to be clear, I am no expert in ALS but have a fair knowledge of spinal muscular atrophies; hence my reaction. Thanks to share your thoughts. kashmiri 16:49, 10 October 2012 (UTC)
An unproportionately lengthy section titled "Head injuries as a cause of ALS" was added today by User:Eric.laporta. Its text IMHO somewhat lacks on encyclopaedic style and is poorly referenced (mainly to primary sources and newspapers, otherwise WP:OR). As such in my opinion it cannot go into the article. I am moving it here before blanking the section so that it can be worked on if anyone is interested.
PMND
was invoked but never defined (see the
help page).Biography
was invoked but never defined (see the
help page).{{
cite journal}}
: Cite journal requires |journal=
(
help); Text "Journal of the Neurological Sciences" ignored (
help)