TRIL | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | TRIL, KIAA0644, TLR4 interactor with leucine rich repeats | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 613356; MGI: 1914123; HomoloGene: 69404; GeneCards: TRIL; OMA: TRIL - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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KIAA0644, also known as TRIL or TLR4 interactor with leucine rich repeats, is a protein that in humans is encoded by the KIAA0644 gene. [5]
The exact function of KIAA0644 is not known. It is, however, a member of the leucine-rich repeat family of proteins, which are known to be involved in protein-protein interactions. This protein is known to interact with the TLR4 protein.
TRIL is a component of the TLR4 complex and is induced in a number of cell types by lipopolysaccharide (LPS). [6]
The main isoform of the human protein is 811 amino long and is composed primarily of leucine (17%), alanine and arginine (~10%), and glycine (~ 8.5%) residues. The protein sequence is predicted to consists mostly of α-helices and a few β-sheet
KIAA0644 is conserved well among mammals but can be found in all chordates with lower sequence identities.
The KIAA0644 gene is neighbors to mRNA-cAMP responsive element binding gene downstream and mRNA carboxypeptidase and serine carboxypeptidase gene upstream [7] [8]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
TRIL | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | TRIL, KIAA0644, TLR4 interactor with leucine rich repeats | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 613356; MGI: 1914123; HomoloGene: 69404; GeneCards: TRIL; OMA: TRIL - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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KIAA0644, also known as TRIL or TLR4 interactor with leucine rich repeats, is a protein that in humans is encoded by the KIAA0644 gene. [5]
The exact function of KIAA0644 is not known. It is, however, a member of the leucine-rich repeat family of proteins, which are known to be involved in protein-protein interactions. This protein is known to interact with the TLR4 protein.
TRIL is a component of the TLR4 complex and is induced in a number of cell types by lipopolysaccharide (LPS). [6]
The main isoform of the human protein is 811 amino long and is composed primarily of leucine (17%), alanine and arginine (~10%), and glycine (~ 8.5%) residues. The protein sequence is predicted to consists mostly of α-helices and a few β-sheet
KIAA0644 is conserved well among mammals but can be found in all chordates with lower sequence identities.
The KIAA0644 gene is neighbors to mRNA-cAMP responsive element binding gene downstream and mRNA carboxypeptidase and serine carboxypeptidase gene upstream [7] [8]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.