Inactivating mutations in TMC6 or TMC8 have been implicated as the genetic cause of the rare skin disorder
epidermodysplasia verruciformis,[7] which is characterized by abnormal susceptibility to human papillomaviruses (HPVs) of the skin resulting in the growth of scaly
macules and
papules, particularly on the hands and feet.
Zuo YG, Ma D, Zhang Y, et al. (2007). "Identification of a novel mutation and a genetic polymorphism of EVER1 gene in two families with epidermodysplasia verruciformis". J. Dermatol. Sci. 44 (3): 153–9.
doi:
10.1016/j.jdermsci.2006.08.013.
PMID17008061.
Donfack J, Buchinsky FJ, Derkay CS, et al. (2006). "Four mutations in Epidermodysplasia verruciformis 1 (EVER1) gene are not contributors to susceptibility in RRP". Int. J. Pediatr. Otorhinolaryngol. 70 (7): 1235–40.
doi:
10.1016/j.ijporl.2006.01.001.
PMID16487602.
Inactivating mutations in TMC6 or TMC8 have been implicated as the genetic cause of the rare skin disorder
epidermodysplasia verruciformis,[7] which is characterized by abnormal susceptibility to human papillomaviruses (HPVs) of the skin resulting in the growth of scaly
macules and
papules, particularly on the hands and feet.
Zuo YG, Ma D, Zhang Y, et al. (2007). "Identification of a novel mutation and a genetic polymorphism of EVER1 gene in two families with epidermodysplasia verruciformis". J. Dermatol. Sci. 44 (3): 153–9.
doi:
10.1016/j.jdermsci.2006.08.013.
PMID17008061.
Donfack J, Buchinsky FJ, Derkay CS, et al. (2006). "Four mutations in Epidermodysplasia verruciformis 1 (EVER1) gene are not contributors to susceptibility in RRP". Int. J. Pediatr. Otorhinolaryngol. 70 (7): 1235–40.
doi:
10.1016/j.ijporl.2006.01.001.
PMID16487602.