TLU may mean:

Computing

• Tape Library Unit, an individual computer storage tape library
• Threshold Logical Unit in neural networks

Universities

• Tallinn University
• Texas Lutheran University
• "The Lords University", a jocular acronym referring to BYU, Brigham Young University

Transportation

• Golfo de Morrosquillo Airport (IATA airport code: TLU; ICAO airport code: SKTL) in Tolú, Sucre, Colombia
• Aero Toluca Internactional (ICAO airline code: TLU), see List of airline codes (A)
• The London Underground, the subway of London, England, UK

Other uses

• The Last of Us (series), a video game series and media franchise
  • The Last of Us (2013 videogame) first game in the series
• Tulehu language (ISO 639 language code: tlu)
• St. Kitts and Nevis Trades and Labour Union
• Tropical Livestock Unit

This disambiguation page lists articles associated with the title TLU.
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