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Synaptic pharmacology is the study of drugs that act on the synapses. It deals with the composition, uses, and effects of drugs that may enhance ( receptor) or diminish (blocker) activity at the synapse, which is the junction across which a nerve impulse passes from an axon terminal to a neuron, muscle cell, or gland cell.
A partial list of pharmacological agents that act at synapses follows.
Channel, Receptor, or Phenomenon | Antagonist or Blocker |
---|---|
adenosine | DCPGX, ZM241385, anoxinine |
AMPA-R | NBQX |
AMPA-R desensitization | cyclothiazide (CTZ) |
cannabinoid | AM-251 |
GABAA | bicuculline, [1] gabazine [1] |
GABAB | CGP-54626 |
glycine | strychnine |
kainate R | .. |
metabotropic GluR, broad | MCPG, [2] pertussis toxin, NEM |
muscarinic AChR | atropine, Scopolamine |
nicotinic AChR | bungarotoxin, curare, DhBe |
NMDA-R | APV |
![]() | This article has multiple issues. Please help
improve it or discuss these issues on the
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Synaptic pharmacology is the study of drugs that act on the synapses. It deals with the composition, uses, and effects of drugs that may enhance ( receptor) or diminish (blocker) activity at the synapse, which is the junction across which a nerve impulse passes from an axon terminal to a neuron, muscle cell, or gland cell.
A partial list of pharmacological agents that act at synapses follows.
Channel, Receptor, or Phenomenon | Antagonist or Blocker |
---|---|
adenosine | DCPGX, ZM241385, anoxinine |
AMPA-R | NBQX |
AMPA-R desensitization | cyclothiazide (CTZ) |
cannabinoid | AM-251 |
GABAA | bicuculline, [1] gabazine [1] |
GABAB | CGP-54626 |
glycine | strychnine |
kainate R | .. |
metabotropic GluR, broad | MCPG, [2] pertussis toxin, NEM |
muscarinic AChR | atropine, Scopolamine |
nicotinic AChR | bungarotoxin, curare, DhBe |
NMDA-R | APV |