In molecular biology, Streptococcus sRNAs are small RNAs produced by species of Streptococcus bacteria. Several screens (both computational and experimental) have identified numerous sRNAs in different species and strains of Streptococcus including S. pneumoniae, [1] [2] [3] [4] S. pyogenes, [5] [6] [7] S. agalactiae [8] and S.mutans. [9] The function of most of these is currently unknown, however a few have been characterised including FasX small RNA. [10] Many sRNAs have roles in pathogenesis. [3]
- ^ Tsui HC, Mukherjee D, Ray VA, Sham LT, Feig AL, Winkler ME (January 2010). "Identification and characterization of noncoding small RNAs in Streptococcus pneumoniae serotype 2 strain D39". Journal of Bacteriology. 192 (1): 264–279. doi: 10.1128/JB.01204-09. PMC 2798261. PMID 19854910.
- ^ Kumar R, Shah P, Swiatlo E, Burgess SC, Lawrence ML, Nanduri B (June 3, 2010). "Identification of novel non-coding small RNAs from Streptococcus pneumoniae TIGR4 using high-resolution genome tiling arrays". BMC Genomics. 11: 350. doi: 10.1186/1471-2164-11-350. PMC 2887815. PMID 20525227.
- ^ a b Mann B, van Opijnen T, Wang J, Obert C, Wang YD, Carter R, McGoldrick DJ, Ridout G, Camilli A, Tuomanen EI, Rosch JW (2012). "Control of virulence by small RNAs in Streptococcus pneumoniae". PLOS Pathog. 8 (7): e1002788. doi: 10.1371/journal.ppat.1002788. PMC 3395615. PMID 22807675.
- ^ Acebo, Paloma; Martin-Galiano, Antonio J.; Navarro, Sara; Zaballos, Angel; Amblar, Mónica (March 2012). "Identification of 88 regulatory small RNAs in the TIGR4 strain of the human pathogen Streptococcus pneumoniae". RNA. 18 (3): 530–546. doi: 10.1261/rna.027359.111. PMC 3285940. PMID 22274957.
- ^ Perez N, Treviño J, Liu Z, Ho SC, Babitzke P, Sumby P (November 2, 2009). "A genome-wide analysis of small regulatory RNAs in the human pathogen group A Streptococcus". PLOS ONE. 4 (11): e7668. Bibcode: 2009PLoSO...4.7668P. doi: 10.1371/journal.pone.0007668. PMC 2765633. PMID 19888332.
- ^ Mraheil MA, Billion A, Kuenne C, Pischimarov J, Kreikemeyer B, Engelmann S, Hartke A, Giard JC, Rupnik M, Vorwerk S, Beier M, Retey J, Hartsch T, Jacob A, Cemič F, Hemberger J, Chakraborty T, Hain T (November 2010). "Comparative genome-wide analysis of small RNAs of major Gram-positive pathogens: from identification to application". Microbial Biotechnology. 3 (6): 658–676. doi: 10.1111/j.1751-7915.2010.00171.x. PMC 3815340. PMID 21255362.
- ^ Patenge N, Billion A, Raasch P, Normann J, Wisniewska-Kucper A, Retey J, Boisguérin V, Hartsch T, Hain T, Kreikemeyer B (October 13, 2012). "Identification of novel growth phase- and media-dependent small non-coding RNAs in Streptococcus pyogenes M49 using intergenic tiling arrays". BMC Genomics. 13: 550. doi: 10.1186/1471-2164-13-550. PMC 3542284. PMID 23062031.
- ^ Pichon C, du Merle L, Caliot ME, Trieu-Cuot P, Le Bouguénec C (April 2012). "An in silico model for identification of small RNAs in whole bacterial genomes: characterization of antisense RNAs in pathogenic Escherichia coli and Streptococcus agalactiae strains". Nucleic Acids Research. 40 (7): 2846–2861. doi: 10.1093/nar/gkr1141. PMC 3326304. PMID 22139924.
- ^ Xia L, Xia W, Li S, Li W, Liu J, Ding H, Li J, Li H, Chen Y, Su X, Wang W, Sun L, Wang C, Shao N, Chu B (June 2012). "Identification and expression of small non-coding RNA, L10-Leader, in different growth phases of Streptococcus mutans". Nucleic Acid Therapeutics. 22 (3): 177–186. doi: 10.1089/nat.2011.0339. PMID 22468692.
- ^ Liu Z, Treviño J, Ramirez-Peña E, Sumby P (October 2012). "The small regulatory RNA FasX controls pilus expression and adherence in the human bacterial pathogen group A Streptococcus". Molecular Microbiology. 86 (1): 140–154. doi: 10.1111/j.1365-2958.2012.08178.x. PMC 3456998. PMID 22882718.
 | This molecular biology article is a stub. You can help Wikipedia by expanding it. |
In molecular biology, Streptococcus sRNAs are small RNAs produced by species of Streptococcus bacteria. Several screens (both computational and experimental) have identified numerous sRNAs in different species and strains of Streptococcus including S. pneumoniae, [1] [2] [3] [4] S. pyogenes, [5] [6] [7] S. agalactiae [8] and S.mutans. [9] The function of most of these is currently unknown, however a few have been characterised including FasX small RNA. [10] Many sRNAs have roles in pathogenesis. [3]
- ^ Tsui HC, Mukherjee D, Ray VA, Sham LT, Feig AL, Winkler ME (January 2010). "Identification and characterization of noncoding small RNAs in Streptococcus pneumoniae serotype 2 strain D39". Journal of Bacteriology. 192 (1): 264–279. doi: 10.1128/JB.01204-09. PMC 2798261. PMID 19854910.
- ^ Kumar R, Shah P, Swiatlo E, Burgess SC, Lawrence ML, Nanduri B (June 3, 2010). "Identification of novel non-coding small RNAs from Streptococcus pneumoniae TIGR4 using high-resolution genome tiling arrays". BMC Genomics. 11: 350. doi: 10.1186/1471-2164-11-350. PMC 2887815. PMID 20525227.
- ^ a b Mann B, van Opijnen T, Wang J, Obert C, Wang YD, Carter R, McGoldrick DJ, Ridout G, Camilli A, Tuomanen EI, Rosch JW (2012). "Control of virulence by small RNAs in Streptococcus pneumoniae". PLOS Pathog. 8 (7): e1002788. doi: 10.1371/journal.ppat.1002788. PMC 3395615. PMID 22807675.
- ^ Acebo, Paloma; Martin-Galiano, Antonio J.; Navarro, Sara; Zaballos, Angel; Amblar, Mónica (March 2012). "Identification of 88 regulatory small RNAs in the TIGR4 strain of the human pathogen Streptococcus pneumoniae". RNA. 18 (3): 530–546. doi: 10.1261/rna.027359.111. PMC 3285940. PMID 22274957.
- ^ Perez N, Treviño J, Liu Z, Ho SC, Babitzke P, Sumby P (November 2, 2009). "A genome-wide analysis of small regulatory RNAs in the human pathogen group A Streptococcus". PLOS ONE. 4 (11): e7668. Bibcode: 2009PLoSO...4.7668P. doi: 10.1371/journal.pone.0007668. PMC 2765633. PMID 19888332.
- ^ Mraheil MA, Billion A, Kuenne C, Pischimarov J, Kreikemeyer B, Engelmann S, Hartke A, Giard JC, Rupnik M, Vorwerk S, Beier M, Retey J, Hartsch T, Jacob A, Cemič F, Hemberger J, Chakraborty T, Hain T (November 2010). "Comparative genome-wide analysis of small RNAs of major Gram-positive pathogens: from identification to application". Microbial Biotechnology. 3 (6): 658–676. doi: 10.1111/j.1751-7915.2010.00171.x. PMC 3815340. PMID 21255362.
- ^ Patenge N, Billion A, Raasch P, Normann J, Wisniewska-Kucper A, Retey J, Boisguérin V, Hartsch T, Hain T, Kreikemeyer B (October 13, 2012). "Identification of novel growth phase- and media-dependent small non-coding RNAs in Streptococcus pyogenes M49 using intergenic tiling arrays". BMC Genomics. 13: 550. doi: 10.1186/1471-2164-13-550. PMC 3542284. PMID 23062031.
- ^ Pichon C, du Merle L, Caliot ME, Trieu-Cuot P, Le Bouguénec C (April 2012). "An in silico model for identification of small RNAs in whole bacterial genomes: characterization of antisense RNAs in pathogenic Escherichia coli and Streptococcus agalactiae strains". Nucleic Acids Research. 40 (7): 2846–2861. doi: 10.1093/nar/gkr1141. PMC 3326304. PMID 22139924.
- ^ Xia L, Xia W, Li S, Li W, Liu J, Ding H, Li J, Li H, Chen Y, Su X, Wang W, Sun L, Wang C, Shao N, Chu B (June 2012). "Identification and expression of small non-coding RNA, L10-Leader, in different growth phases of Streptococcus mutans". Nucleic Acid Therapeutics. 22 (3): 177–186. doi: 10.1089/nat.2011.0339. PMID 22468692.
- ^ Liu Z, Treviño J, Ramirez-Peña E, Sumby P (October 2012). "The small regulatory RNA FasX controls pilus expression and adherence in the human bacterial pathogen group A Streptococcus". Molecular Microbiology. 86 (1): 140–154. doi: 10.1111/j.1365-2958.2012.08178.x. PMC 3456998. PMID 22882718.
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