A user with 50 edits. Account created on 8 March 2017.
31 July 2023
- 16:34 16:34, 31 July 2023 diff hist +12 Lorien Trust No edit summary
13 April 2023
- 18:31 18:31, 13 April 2023 diff hist +111 Ranolazine No edit summary
- 18:28 18:28, 13 April 2023 diff hist +9 Ranolazine 7 hrs apparent half life of MR preparation. Less for drug - https://pubmed.ncbi.nlm.nih.gov/16640453/#:~:text=Elimination%20half%2Dlife%20of%20ranolazine,(flip%2Dflop%20kinetics).
1 September 2022
- 16:17 16:17, 1 September 2022 diff hist +1 Levetiracetam →Excretion
25 August 2022
- 22:11 22:11, 25 August 2022 diff hist +1 Lorien Trust No edit summary
- 21:40 21:40, 25 August 2022 diff hist +14 Lorien Trust No edit summary
- 21:38 21:38, 25 August 2022 diff hist +44 Lorien Trust No edit summary
4 August 2022
- 14:52 14:52, 4 August 2022 diff hist +6 Metronidazole →Medical uses: "cream" added to image - because it is...
23 May 2022
- 10:51 10:51, 23 May 2022 diff hist −123 Sodium butyrate Alleged effect of legumes longevity is trivia unrelated to the chemical, unless well evidenced that it is the chemical that has this effect not the legumes/lifestyle.
18 October 2021
- 11:38 11:38, 18 October 2021 diff hist +36 Remifentanil →Potency: First reference looks at analgesia-sedation i.e., the sedation score, not analgesia, and is a single small trial so on this weak evidence we probably shouldn't state it as a fact that remifentanil is superior
11 May 2021
- 08:54 08:54, 11 May 2021 diff hist −2 Mucormycosis →Risk factors
- 08:53 08:53, 11 May 2021 diff hist −78 Mucormycosis Tidied text around effect of corticosteroids
27 March 2021
- 12:36 12:36, 27 March 2021 diff hist +118 Extended-release morphine →Structure: Unable to confirm source for claims of plastic spheroids with pH dependent pores. UK manufacturer's datasheets do not detail spheroids' presence in faeces in contrast to what is normal for similar formulations (Episenta, Asacol etc) Personal communication with Ethylpharm - UK manufacturer of Zomorph MR morphine brand was fruitless.
22 March 2021
- 11:49 11:49, 22 March 2021 diff hist +22 Metronidazole Implying that it it may not be considered safe in breastfeeding misrepresents the consensus and cause undue worry.
21 March 2021
- 22:15 22:15, 21 March 2021 diff hist +71 Lorien Trust No edit summary
4 September 2020
- 13:12 13:12, 4 September 2020 diff hist +13 Metronidazole →Pharmacokinetics: changed wording, linked bioavailability
5 May 2020
- 16:32 16:32, 5 May 2020 diff hist −26 List of unproven methods against COVID-19 →Herbs and spices
10 March 2020
- 10:57 10:57, 10 March 2020 diff hist +85 List of withdrawn drugs No edit summary
- 10:52 10:52, 10 March 2020 diff hist +142 List of withdrawn drugs No edit summary
- 10:50 10:50, 10 March 2020 diff hist +11 List of withdrawn drugs No edit summary
- 10:48 10:48, 10 March 2020 diff hist +290 List of withdrawn drugs No edit summary
21 February 2020
- 16:26 16:26, 21 February 2020 diff hist +97 Metronidazole No edit summary
20 February 2020
- 21:19 21:19, 20 February 2020 diff hist −6 Cannabidiol →Epilepsy: "minor" adverse effects is entirely subjective
- 16:28 16:28, 20 February 2020 diff hist +1,461 Caphosol No edit summary
9 September 2019
- 15:25 15:25, 9 September 2019 diff hist +2 User talk:Doc James →Metronidazole benzoate
- 15:24 15:24, 9 September 2019 diff hist +882 User talk:Doc James →Metronidazole benzoate
6 September 2019
- 16:21 16:21, 6 September 2019 diff hist +2 m Metronidazole →Medical uses
- 16:19 16:19, 6 September 2019 diff hist +43 Metronidazole Metronidazole benzoate hydrolysed in GI tract rather then stomach, and unsuitability in feeding tubes is unsupported by primary evidence and unreferenced by authors speculating it to be the case.
- 15:52 15:52, 6 September 2019 diff hist +386 User talk:Doc James →Metronidazole benzoate
- 15:49 15:49, 6 September 2019 diff hist +99 User talk:Doc James →Metronidazole benzoate
- 15:48 15:48, 6 September 2019 diff hist +1,197 User talk:Doc James →Metronidazole benzoate
3 September 2019
- 12:00 12:00, 3 September 2019 diff hist +997 User talk:Doc James →Metronidazole benzoate: new section
2 September 2019
- 14:53 14:53, 2 September 2019 diff hist +120 Metronidazole →Medical uses: Paper reference 13 does not provide a source for the claim that metronidazole benzoate requires hydrolysis in the stomach for efficacy and in personal communication the authors were unable to provide a source. I suspect it is long-running folk-wisdom; without evidence it should not be asserted as fact.
- 14:33 14:33, 2 September 2019 diff hist +58 Iodised salt Reference 3 only supports "rapid" loss at 100% RH and 40C
25 June 2019
18 December 2018
- 10:36 10:36, 18 December 2018 diff hist +78 Nitrofurantoin This uncommon reaction may occur 1 month to 6 years after starting the drug and is usually related to its total lifetime dose.{{Citation needed|reason= source for lifetinme dose claim|date=December 2018}}
12 November 2018
- 10:31 10:31, 12 November 2018 diff hist −314 Aminolevulinic acid →Activation of mitochondria: thereby increasing glucose consumption and it helps in addressing the problem of low energy levels of patients.<ref>Bratic, I., Trifunovic, A. (2010). Mitochondrial energy and ageing. Biochimica et Biophysica Acta-Bioenergetics, 1797,961-967.</ref>" deletd comment as claim is not supported by the referencece provided. "Energy levels" is a nonsense term and smacks or quackery and vested interest.
8 November 2018
- 17:16 17:16, 8 November 2018 diff hist −20 Medical cannabis Whole-plant cannabis for medicinal use is not legal in the UK. The recent legal changes allow for cannabis-based medicinal products. See https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/753172/Factsheet_-_Cannabis_CBD_and_Cannabinoids_-_v_1_2__2018.pdf
5 November 2018
- 09:41 09:41, 5 November 2018 diff hist −6 Eptifibatide →Side effects
23 May 2018
- 09:17 09:17, 23 May 2018 diff hist +1 Levothyroxine No edit summary
22 January 2018
- 10:19 10:19, 22 January 2018 diff hist +153 Metronidazole Added link to source Tags: Mobile edit Mobile web edit
- 10:14 10:14, 22 January 2018 diff hist +322 Metronidazole Added note on metronidazole suspension. Tags: Mobile edit Mobile web edit
24 August 2017
- 08:52 08:52, 24 August 2017 diff hist −207 m Hydroa vacciniforme Mention of Heliocare Ultra-D removed pending any sort of credible evidence!
10 April 2017
- 11:52 11:52, 10 April 2017 diff hist +84 Hydroa vacciniforme No edit summary
- 11:50 11:50, 10 April 2017 diff hist +19 Hydroa vacciniforme No edit summary
24 March 2017
- 14:14 14:14, 24 March 2017 diff hist +232 Pholcodine →External links
- 14:12 14:12, 24 March 2017 diff hist −63 Pholcodine →References
- 14:12 14:12, 24 March 2017 diff hist +63 Pholcodine →References
- 14:10 14:10, 24 March 2017 diff hist +609 Pholcodine →Anaphylaxis During General Anaesthesia
17 March 2017
- 16:27 16:27, 17 March 2017 diff hist +16 Clioquinol No edit summary
A user with 50 edits. Account created on 8 March 2017.
31 July 2023
- 16:34 16:34, 31 July 2023 diff hist +12 Lorien Trust No edit summary
13 April 2023
- 18:31 18:31, 13 April 2023 diff hist +111 Ranolazine No edit summary
- 18:28 18:28, 13 April 2023 diff hist +9 Ranolazine 7 hrs apparent half life of MR preparation. Less for drug - https://pubmed.ncbi.nlm.nih.gov/16640453/#:~:text=Elimination%20half%2Dlife%20of%20ranolazine,(flip%2Dflop%20kinetics).
1 September 2022
- 16:17 16:17, 1 September 2022 diff hist +1 Levetiracetam →Excretion
25 August 2022
- 22:11 22:11, 25 August 2022 diff hist +1 Lorien Trust No edit summary
- 21:40 21:40, 25 August 2022 diff hist +14 Lorien Trust No edit summary
- 21:38 21:38, 25 August 2022 diff hist +44 Lorien Trust No edit summary
4 August 2022
- 14:52 14:52, 4 August 2022 diff hist +6 Metronidazole →Medical uses: "cream" added to image - because it is...
23 May 2022
- 10:51 10:51, 23 May 2022 diff hist −123 Sodium butyrate Alleged effect of legumes longevity is trivia unrelated to the chemical, unless well evidenced that it is the chemical that has this effect not the legumes/lifestyle.
18 October 2021
- 11:38 11:38, 18 October 2021 diff hist +36 Remifentanil →Potency: First reference looks at analgesia-sedation i.e., the sedation score, not analgesia, and is a single small trial so on this weak evidence we probably shouldn't state it as a fact that remifentanil is superior
11 May 2021
- 08:54 08:54, 11 May 2021 diff hist −2 Mucormycosis →Risk factors
- 08:53 08:53, 11 May 2021 diff hist −78 Mucormycosis Tidied text around effect of corticosteroids
27 March 2021
- 12:36 12:36, 27 March 2021 diff hist +118 Extended-release morphine →Structure: Unable to confirm source for claims of plastic spheroids with pH dependent pores. UK manufacturer's datasheets do not detail spheroids' presence in faeces in contrast to what is normal for similar formulations (Episenta, Asacol etc) Personal communication with Ethylpharm - UK manufacturer of Zomorph MR morphine brand was fruitless.
22 March 2021
- 11:49 11:49, 22 March 2021 diff hist +22 Metronidazole Implying that it it may not be considered safe in breastfeeding misrepresents the consensus and cause undue worry.
21 March 2021
- 22:15 22:15, 21 March 2021 diff hist +71 Lorien Trust No edit summary
4 September 2020
- 13:12 13:12, 4 September 2020 diff hist +13 Metronidazole →Pharmacokinetics: changed wording, linked bioavailability
5 May 2020
- 16:32 16:32, 5 May 2020 diff hist −26 List of unproven methods against COVID-19 →Herbs and spices
10 March 2020
- 10:57 10:57, 10 March 2020 diff hist +85 List of withdrawn drugs No edit summary
- 10:52 10:52, 10 March 2020 diff hist +142 List of withdrawn drugs No edit summary
- 10:50 10:50, 10 March 2020 diff hist +11 List of withdrawn drugs No edit summary
- 10:48 10:48, 10 March 2020 diff hist +290 List of withdrawn drugs No edit summary
21 February 2020
- 16:26 16:26, 21 February 2020 diff hist +97 Metronidazole No edit summary
20 February 2020
- 21:19 21:19, 20 February 2020 diff hist −6 Cannabidiol →Epilepsy: "minor" adverse effects is entirely subjective
- 16:28 16:28, 20 February 2020 diff hist +1,461 Caphosol No edit summary
9 September 2019
- 15:25 15:25, 9 September 2019 diff hist +2 User talk:Doc James →Metronidazole benzoate
- 15:24 15:24, 9 September 2019 diff hist +882 User talk:Doc James →Metronidazole benzoate
6 September 2019
- 16:21 16:21, 6 September 2019 diff hist +2 m Metronidazole →Medical uses
- 16:19 16:19, 6 September 2019 diff hist +43 Metronidazole Metronidazole benzoate hydrolysed in GI tract rather then stomach, and unsuitability in feeding tubes is unsupported by primary evidence and unreferenced by authors speculating it to be the case.
- 15:52 15:52, 6 September 2019 diff hist +386 User talk:Doc James →Metronidazole benzoate
- 15:49 15:49, 6 September 2019 diff hist +99 User talk:Doc James →Metronidazole benzoate
- 15:48 15:48, 6 September 2019 diff hist +1,197 User talk:Doc James →Metronidazole benzoate
3 September 2019
- 12:00 12:00, 3 September 2019 diff hist +997 User talk:Doc James →Metronidazole benzoate: new section
2 September 2019
- 14:53 14:53, 2 September 2019 diff hist +120 Metronidazole →Medical uses: Paper reference 13 does not provide a source for the claim that metronidazole benzoate requires hydrolysis in the stomach for efficacy and in personal communication the authors were unable to provide a source. I suspect it is long-running folk-wisdom; without evidence it should not be asserted as fact.
- 14:33 14:33, 2 September 2019 diff hist +58 Iodised salt Reference 3 only supports "rapid" loss at 100% RH and 40C
25 June 2019
18 December 2018
- 10:36 10:36, 18 December 2018 diff hist +78 Nitrofurantoin This uncommon reaction may occur 1 month to 6 years after starting the drug and is usually related to its total lifetime dose.{{Citation needed|reason= source for lifetinme dose claim|date=December 2018}}
12 November 2018
- 10:31 10:31, 12 November 2018 diff hist −314 Aminolevulinic acid →Activation of mitochondria: thereby increasing glucose consumption and it helps in addressing the problem of low energy levels of patients.<ref>Bratic, I., Trifunovic, A. (2010). Mitochondrial energy and ageing. Biochimica et Biophysica Acta-Bioenergetics, 1797,961-967.</ref>" deletd comment as claim is not supported by the referencece provided. "Energy levels" is a nonsense term and smacks or quackery and vested interest.
8 November 2018
- 17:16 17:16, 8 November 2018 diff hist −20 Medical cannabis Whole-plant cannabis for medicinal use is not legal in the UK. The recent legal changes allow for cannabis-based medicinal products. See https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/753172/Factsheet_-_Cannabis_CBD_and_Cannabinoids_-_v_1_2__2018.pdf
5 November 2018
- 09:41 09:41, 5 November 2018 diff hist −6 Eptifibatide →Side effects
23 May 2018
- 09:17 09:17, 23 May 2018 diff hist +1 Levothyroxine No edit summary
22 January 2018
- 10:19 10:19, 22 January 2018 diff hist +153 Metronidazole Added link to source Tags: Mobile edit Mobile web edit
- 10:14 10:14, 22 January 2018 diff hist +322 Metronidazole Added note on metronidazole suspension. Tags: Mobile edit Mobile web edit
24 August 2017
- 08:52 08:52, 24 August 2017 diff hist −207 m Hydroa vacciniforme Mention of Heliocare Ultra-D removed pending any sort of credible evidence!
10 April 2017
- 11:52 11:52, 10 April 2017 diff hist +84 Hydroa vacciniforme No edit summary
- 11:50 11:50, 10 April 2017 diff hist +19 Hydroa vacciniforme No edit summary
24 March 2017
- 14:14 14:14, 24 March 2017 diff hist +232 Pholcodine →External links
- 14:12 14:12, 24 March 2017 diff hist −63 Pholcodine →References
- 14:12 14:12, 24 March 2017 diff hist +63 Pholcodine →References
- 14:10 14:10, 24 March 2017 diff hist +609 Pholcodine →Anaphylaxis During General Anaesthesia
17 March 2017
- 16:27 16:27, 17 March 2017 diff hist +16 Clioquinol No edit summary