From Wikipedia, the free encyclopedia
SMART
Content
Description Identification scheme for protein domains.
Data types
captured
Protein domains
Organismsall
Contact
Research center European Molecular Biology Laboratory
Primary citation PMID  18978020
Access
Website http://smart.embl-heidelberg.de
Miscellaneous
LicenseFree to academics, but not commercial users
Version7
Curation policyYes

Simple Modular Architecture Research Tool (SMART) is a biological database that is used in the identification and analysis of protein domains within protein sequences. [1] [2] SMART uses profile-hidden Markov models built from multiple sequence alignments to detect protein domains in protein sequences. The most recent release of SMART contains 1,204 domain models. [3] Data from SMART was used in creating the Conserved Domain Database collection and is also distributed as part of the InterPro database. [4] The database is hosted by the European Molecular Biology Laboratory in Heidelberg.

References

  1. ^ Schultz J, Milpetz F, Bork P, Ponting CP (May 1998). "SMART, a simple modular architecture research tool: identification of signaling domains" (PDF). Proc. Natl. Acad. Sci. U.S.A. 95 (11): 5857–64. Bibcode: 1998PNAS...95.5857S. doi: 10.1073/pnas.95.11.5857. PMC  34487. PMID  9600884.
  2. ^ Letunic I, Doerks T, Bork P (January 2009). "SMART 6: recent updates and new developments". Nucleic Acids Res. 37 (Database issue): D229–32. doi: 10.1093/nar/gkn808. PMC  2686533. PMID  18978020.
  3. ^ Letunic, Ivica; Doerks, Tobias; Bork, Peer (January 2015). "SMART: recent updates, new developments and status in 2015". Nucleic Acids Research. 43 (Database issue): D257–260. doi: 10.1093/nar/gku949. ISSN  1362-4962. PMC  4384020. PMID  25300481.
  4. ^ Mulder NJ, Apweiler R, Attwood TK, et al. (September 2002). "InterPro: an integrated documentation resource for protein families, domains and functional sites". Brief. Bioinformatics. 3 (3): 225–35. doi: 10.1093/bib/3.3.225. PMID  12230031.

External links


From Wikipedia, the free encyclopedia
SMART
Content
Description Identification scheme for protein domains.
Data types
captured
Protein domains
Organismsall
Contact
Research center European Molecular Biology Laboratory
Primary citation PMID  18978020
Access
Website http://smart.embl-heidelberg.de
Miscellaneous
LicenseFree to academics, but not commercial users
Version7
Curation policyYes

Simple Modular Architecture Research Tool (SMART) is a biological database that is used in the identification and analysis of protein domains within protein sequences. [1] [2] SMART uses profile-hidden Markov models built from multiple sequence alignments to detect protein domains in protein sequences. The most recent release of SMART contains 1,204 domain models. [3] Data from SMART was used in creating the Conserved Domain Database collection and is also distributed as part of the InterPro database. [4] The database is hosted by the European Molecular Biology Laboratory in Heidelberg.

References

  1. ^ Schultz J, Milpetz F, Bork P, Ponting CP (May 1998). "SMART, a simple modular architecture research tool: identification of signaling domains" (PDF). Proc. Natl. Acad. Sci. U.S.A. 95 (11): 5857–64. Bibcode: 1998PNAS...95.5857S. doi: 10.1073/pnas.95.11.5857. PMC  34487. PMID  9600884.
  2. ^ Letunic I, Doerks T, Bork P (January 2009). "SMART 6: recent updates and new developments". Nucleic Acids Res. 37 (Database issue): D229–32. doi: 10.1093/nar/gkn808. PMC  2686533. PMID  18978020.
  3. ^ Letunic, Ivica; Doerks, Tobias; Bork, Peer (January 2015). "SMART: recent updates, new developments and status in 2015". Nucleic Acids Research. 43 (Database issue): D257–260. doi: 10.1093/nar/gku949. ISSN  1362-4962. PMC  4384020. PMID  25300481.
  4. ^ Mulder NJ, Apweiler R, Attwood TK, et al. (September 2002). "InterPro: an integrated documentation resource for protein families, domains and functional sites". Brief. Bioinformatics. 3 (3): 225–35. doi: 10.1093/bib/3.3.225. PMID  12230031.

External links



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