Serhiy Melnyk (Ukrainian: Сергій Мельник, Russian: Сергей Мельник, Belarusian: Сяргей Мельнік; other transliterations: Sergei, Sergey, Syarhey; Melnik or Melnick) may refer to the following people:

• Serhiy Melnyk (footballer born 1988), Ukrainian football defender
• Serhiy Melnyk (footballer born 1993), Ukrainian football striker
• Serhiy Melnyk (politician) (born 1965), Ukrainian politician
• Syarhey Melnik (born 1995), Belarusian football midfielder

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