Carretera Sancti Spíritus–Yaguajay
Sancti Spíritus–Yaguajay Road
Route information
Length	53 km (33 mi)
Major junctions
North end	Circuito Norte ( Yaguajay)
Major intersections	Autopista A1
South end	Carretera Central ( Sancti Spíritus)
Location
Country	Cuba
Provinces	Sancti Spíritus
Municipalities	Sancti Spíritus, Taguasco, Cabaiguán, Yaguajay
Highway system
Roads in Cuba

The Sancti Spíritus–Yaguajay Road (4–531) is a north-south national highway in Sancti Spíritus Province, Cuba, connecting Sancti Spíritus to the town of Yaguajay. The road has two sections, the northern half of the Circunvalación Sancti Spíritus, the motorway section, south of the intersection with the Autopista A1, and the regular Sancti Spíritus–Yaguajay two lane road, built before the revolution.

In 2017, from October to November, the Autopista A1 closed past the intersection with the 4–531, for repairs, making it so you had to either go down the circunvalación Sancti Spíritus or north to Yaguajay, instead of being able to go straight until Taguasco, then ending at the Maja–Taguasco Road, which was also closed. ^{[1] [2] [3] [4]}

In 2018, there was damages in the road due to the landslides in the El Yigre area, and inter-municipal transport services where temporary closed due to the weather throughout the province. ^{[5] [6]}

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The symbol indicates the motorway section.

Municipality	Location	↓km↓	Destination
Yaguajay	Yaguajay	0	Circuito Norte
Yaguajay	Meneses	10	4–471 – Bamburanao, Zulueta
Yaguajay		12	Road to Iguará – Iguará
Yaguajay		16	Road to Florencia (east), Road to Itabo (south)
Yaguajay	Jarahueca	19	4–571 – General Carrillo
Cabaiguán		33	Cabaiguán–Jíquima Road – Saltadero, Cabaiguán
Taguasco		37	Road to La Larga (going south) – La Larga
Cabaiguán		38	Road to La Larga (going north) – La Larga
Cabaiguán	Tres Palmas	40	Road to Las Damas – Las Damas
Cabaiguán		42	Autopista A1 – Havana, Taguasco
Taguasco		45	Guayo Road – La Esperanza, Guayos
Taguasco		48	Road to Tuinicú – Tuinicú, Zaza del Medio
Sancti Spíritus		53	Carretera Central – Sancti Spíritus, Guayos