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Sambú
District
Country	Panama
Comarca indígena	Emberá-Wounaan
Capital	Puerto Indio
Area
• Total	1,296.4 km2 (500.5 sq mi)
Population  (2010)
• Total	2,286
• Density	1.8/km2 (4.6/sq mi)
Time zone	UTC-5 ( ETZ)

Sambú District is a district (distrito) of Comarca Emberá-Wounaan in Panama. The capital is Puerto Indio. The area of this district is 1296.4 sq. kilometers. It is on the western part of Comarca Emberá-Wounaan. The other side of the Comarca is Cémaco District.

Sambú District is divided administratively into the following corregimientos:

• Río Sábalo
• Jingurudo

• Panama
• Districts of Panama
• Embera-Wounaan, indigenous peoples of Colombia and Panama
• Emberá languages, indigenous language family in Colombia and Panama