From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Serine/threonine-protein kinase 25 is an
enzyme that in humans is encoded by the STK25
gene .
[5]
[6]
[7]
[8]
Interactions
STK25 has been shown to
interact with
STRN ,
[9]
PDCD10
[10] and
MOBKL3 .
[9]
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000115694 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000026277 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Pombo CM, Bonventre JV, Molnar A, Kyriakis J, Force T (Jan 1997).
"Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway" . EMBO J . 15 (17): 4537–46.
doi :
10.1002/j.1460-2075.1996.tb00831.x .
PMC
452183 .
PMID
8887545 .
^ Osada S, Izawa M, Saito R, Mizuno K, Suzuki A, Hirai S, Ohno S (Jun 1997). "YSK1, a novel mammalian protein kinase structurally related to Ste20 and SPS1, but is not involved in the known MAPK pathways". Oncogene . 14 (17): 2047–57.
doi :
10.1038/sj.onc.1201043 .
PMID
9160885 .
S2CID
27210425 .
^ Preisinger C, Short B, De Corte V, Bruyneel E, Haas A, Kopajtich R, Gettemans J, Barr FA (Mar 2004).
"YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta" . J Cell Biol . 164 (7): 1009–20.
doi :
10.1083/jcb.200310061 .
PMC
2172068 .
PMID
15037601 .
^
"Entrez Gene: STK25 serine/threonine kinase 25 (STE20 homolog, yeast)" .
^
a
b Goudreault M, D'Ambrosio LM, Kean MJ, Mullin MJ, Larsen BG, Sanchez A, Chaudhry S, Chen GI, Sicheri F, Nesvizhskii AI, Aebersold R, Raught B, Gingras AC (January 2009).
"A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein" . Mol. Cell. Proteomics . 8 (1): 157–71.
doi :
10.1074/mcp.M800266-MCP200 .
PMC
2621004 .
PMID
18782753 .
^ Rual JF, Venkatesan K, Hao T, et al. (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8.
Bibcode :
2005Natur.437.1173R .
doi :
10.1038/nature04209 .
PMID
16189514 .
S2CID
4427026 .
Further reading
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004).
"Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5.
doi :
10.1038/ng1285 .
PMID
14702039 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Hillier LW, Graves TA, Fulton RS, et al. (2005).
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4" . Nature . 434 (7034): 724–31.
Bibcode :
2005Natur.434..724H .
doi :
10.1038/nature03466 .
PMID
15815621 .
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8.
Bibcode :
2005Natur.437.1173R .
doi :
10.1038/nature04209 .
PMID
16189514 .
S2CID
4427026 .
Findlay GM, Yan L, Procter J, et al. (2007).
"A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling" . Biochem. J . 403 (1): 13–20.
doi :
10.1042/BJ20061881 .
PMC
1828895 .
PMID
17253963 .
Ewing RM, Chu P, Elisma F, et al. (2007).
"Large-scale mapping of human protein-protein interactions by mass spectrometry" . Mol. Syst. Biol . 3 (1): 89.
doi :
10.1038/msb4100134 .
PMC
1847948 .
PMID
17353931 .
Matsuki T, Matthews RT, Cooper JA, van der Brug MP, Cookson MR, Hardy JA, Olson EC, Howell BW (November 2010).
"Reelin and stk25 have opposing roles in neuronal polarization and dendritic Golgi deployment" . Cell . 143 (5): 826–36.
doi :
10.1016/j.cell.2010.10.029 .
PMC
3033572 .
PMID
21111240 .