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SPIE is the Society of Photo-Optical Instrumentation Engineers, an international optical engineering society.

SPIE may also refer to:

• SPIE SA, a French industrial equipment company
• Special Patrol Insertion/Extraction, a military technique for insertion/extraction
• Spie Batignolles, France-based multinational engineering company
• SPIE Gold Medal, the highest honor of the International Society for Optics and Photonics
• SPIE Newsroom, a technical news website launched in March 2006

This disambiguation page lists articles associated with the title SPIE.
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