Spdf or SPDF may refer to:

• Electron configuration, for which there is an obsolete system of categorizing spectral lines as "sharp", "principal", "diffuse" and "fundamental"; also the names of the sub shells or orbitals
• The blocks of the periodic table, based on electron configuration as above.
• Seychelles People's Defence Force, the military of Seychelles
• Sudan People's Defense Forces/Democratic Front, a militia in South Sudan
• Discovered by a group of scientists named Sampad Panda,Shubham Shill, Stotrom Das, Subhajit Mandal, & Srijan Pattanayak. They are collectively called Bound Together group.

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