Sirtuin 4, also known as SIRT4, is a
mitochondrialprotein which in humans is encoded by the SIRT4 gene.[5][6] SIRT4 is member of the mammalian
sirtuin family of proteins, which are
homologs to the yeast Sir2 protein. SIRT4 exhibits NAD+-dependent
deacetylase activity.
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Frye RA (June 1999). "Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity". Biochem. Biophys. Res. Commun. 260 (1): 273–79.
doi:
10.1006/bbrc.1999.0897.
PMID10381378.
Sirtuin 4, also known as SIRT4, is a
mitochondrialprotein which in humans is encoded by the SIRT4 gene.[5][6] SIRT4 is member of the mammalian
sirtuin family of proteins, which are
homologs to the yeast Sir2 protein. SIRT4 exhibits NAD+-dependent
deacetylase activity.
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Frye RA (June 1999). "Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity". Biochem. Biophys. Res. Commun. 260 (1): 273–79.
doi:
10.1006/bbrc.1999.0897.
PMID10381378.