S-adenosyl methionine (SAM) riboswitch, | |
---|---|
![]() Predicted
secondary structure and
sequence conservation of SAM-IV | |
Identifiers | |
Symbol | SAM-IV |
Rfam | RF00634 CL00012 |
Other data | |
RNA type | Cis-reg; riboswitch |
Domain(s) | Bacteria |
SO | SO:0005836 |
PDB structures | PDBe |
SAM-IV riboswitches are a kind of riboswitch that specifically binds S-adenosylmethionine (SAM), [1] a cofactor used in many methylation reactions. Originally identified by bioinformatics, [2] SAM-IV riboswitches are largely confined to the Actinomycetales, an order of Bacteria. Conserved features of SAM-IV riboswitch and experiments imply that they probably share a similar SAM-binding site to another class of SAM-binding riboswitches called SAM-I riboswitches. However, the scaffolds of these two types of riboswitch appear to be quite distinct. The structural relationship between these riboswitch types has been studied. [3] [4]
S-adenosyl methionine (SAM) riboswitch, | |
---|---|
![]() Predicted
secondary structure and
sequence conservation of SAM-IV | |
Identifiers | |
Symbol | SAM-IV |
Rfam | RF00634 CL00012 |
Other data | |
RNA type | Cis-reg; riboswitch |
Domain(s) | Bacteria |
SO | SO:0005836 |
PDB structures | PDBe |
SAM-IV riboswitches are a kind of riboswitch that specifically binds S-adenosylmethionine (SAM), [1] a cofactor used in many methylation reactions. Originally identified by bioinformatics, [2] SAM-IV riboswitches are largely confined to the Actinomycetales, an order of Bacteria. Conserved features of SAM-IV riboswitch and experiments imply that they probably share a similar SAM-binding site to another class of SAM-binding riboswitches called SAM-I riboswitches. However, the scaffolds of these two types of riboswitch appear to be quite distinct. The structural relationship between these riboswitch types has been studied. [3] [4]