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CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.039.094 |
Chemical and physical data | |
Formula | C13H17NO2 |
Molar mass | 219.284 g·mol−1 |
3D model ( JSmol) | |
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Ritalinic acid is a substituted phenethylamine and an inactive major metabolite of the psychostimulant drugs methylphenidate, dexmethylphenidate and ethylphenidate. [1] [2] When administered orally, methylphenidate is extensively metabolized in the liver by hydrolysis of the ester group yielding ritalinic acid. [1] The hydrolysis was found to be catalyzed by carboxylesterase 1 (CES1). [3]
Etymologically, ritalinic acid shares its roots with Ritalin, a common brand name for methylphenidate.
Ritalinic acid is used as an intermediate in the synthesis of methylphenidate and its analogues, such as ethylphenidate and isopropylphenidate.
Clinical data | |
---|---|
ATC code |
|
Legal status | |
Legal status |
|
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.039.094 |
Chemical and physical data | |
Formula | C13H17NO2 |
Molar mass | 219.284 g·mol−1 |
3D model ( JSmol) | |
| |
| |
(verify) |
Ritalinic acid is a substituted phenethylamine and an inactive major metabolite of the psychostimulant drugs methylphenidate, dexmethylphenidate and ethylphenidate. [1] [2] When administered orally, methylphenidate is extensively metabolized in the liver by hydrolysis of the ester group yielding ritalinic acid. [1] The hydrolysis was found to be catalyzed by carboxylesterase 1 (CES1). [3]
Etymologically, ritalinic acid shares its roots with Ritalin, a common brand name for methylphenidate.
Ritalinic acid is used as an intermediate in the synthesis of methylphenidate and its analogues, such as ethylphenidate and isopropylphenidate.