Rho associated coiled-coil containing protein kinase 2 is a protein that in humans is encoded by the ROCK2 gene. [5] Fasudil is an inhibitor of ROCK protein.
The protein encoded by this gene is a serine/ threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
ROCK2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | ROCK2, ROCK-II, Rho associated coiled-coil containing protein kinase 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 604002; MGI: 107926; HomoloGene: 21010; GeneCards: ROCK2; OMA: ROCK2 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Rho associated coiled-coil containing protein kinase 2 is a protein that in humans is encoded by the ROCK2 gene. [5] Fasudil is an inhibitor of ROCK protein.
The protein encoded by this gene is a serine/ threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.