Receptor-interacting serine/threonine-protein kinase 2 is an
enzyme that in humans is encoded by the RIPK2gene.[5][6][7]
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal
caspase recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of
NF-κB and inducer of apoptosis in response to various stimuli.[7]
Yoo NJ, Park WS, Kim SY, et al. (2003). "Nod1, a CARD protein, enhances pro-interleukin-1beta processing through the interaction with pro-caspase-1". Biochem. Biophys. Res. Commun. 299 (4): 652–8.
doi:
10.1016/S0006-291X(02)02714-6.
PMID12459189.
Chen YR, Clark AC (2003). "Equilibrium and kinetic folding of an alpha-helical Greek key protein domain: caspase recruitment domain (CARD) of RICK". Biochemistry. 42 (20): 6310–20.
doi:
10.1021/bi0340752.
PMID12755636.
Receptor-interacting serine/threonine-protein kinase 2 is an
enzyme that in humans is encoded by the RIPK2gene.[5][6][7]
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal
caspase recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of
NF-κB and inducer of apoptosis in response to various stimuli.[7]
Yoo NJ, Park WS, Kim SY, et al. (2003). "Nod1, a CARD protein, enhances pro-interleukin-1beta processing through the interaction with pro-caspase-1". Biochem. Biophys. Res. Commun. 299 (4): 652–8.
doi:
10.1016/S0006-291X(02)02714-6.
PMID12459189.
Chen YR, Clark AC (2003). "Equilibrium and kinetic folding of an alpha-helical Greek key protein domain: caspase recruitment domain (CARD) of RICK". Biochemistry. 42 (20): 6310–20.
doi:
10.1021/bi0340752.
PMID12755636.