Ras-specific guanine nucleotide-releasing factor 2 is a
protein that in humans is encoded by the RASGRF2gene.[5]
RAS (MIM 190020) GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. Guanine-nucleotide exchange factors (GEFs), such as RASGRFs, stimulate the conversion of the GDP-bound form into the active form.[supplied by OMIM][5]
Variations in this gene has been shown to be linked to the propensity to
binge drink by teenagers.[6]
Fam NP, Zhang LJ, Rommens JM, et al. (1997). "Mapping of the Ras-GRF2 gene (GRF2) to mouse chromosome 13C3-D1 and human chromosome 5q13, near the Ras-GAP gene". Genomics. 39 (1): 118–20.
doi:
10.1006/geno.1996.4484.
PMID9027497.
Ras-specific guanine nucleotide-releasing factor 2 is a
protein that in humans is encoded by the RASGRF2gene.[5]
RAS (MIM 190020) GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. Guanine-nucleotide exchange factors (GEFs), such as RASGRFs, stimulate the conversion of the GDP-bound form into the active form.[supplied by OMIM][5]
Variations in this gene has been shown to be linked to the propensity to
binge drink by teenagers.[6]
Fam NP, Zhang LJ, Rommens JM, et al. (1997). "Mapping of the Ras-GRF2 gene (GRF2) to mouse chromosome 13C3-D1 and human chromosome 5q13, near the Ras-GAP gene". Genomics. 39 (1): 118–20.
doi:
10.1006/geno.1996.4484.
PMID9027497.