Proteomimetics are molecules that mimic certain protein characteristics such as shape, binding properties or enzymatic activity. [1] While conceptually linked to peptidomimetics which mimic short peptide sequences or secondary structures, proteomimetics recapitulate tertiary structures. This can involve the mimicry of entire protein domains [2] or fragments thereof. [3] Proteomimetic approaches can range from entirely abiotic scaffolds [2] to specific main chain and side chain-modifications. [4] [5]
Proteomimetics are molecules that mimic certain protein characteristics such as shape, binding properties or enzymatic activity. [1] While conceptually linked to peptidomimetics which mimic short peptide sequences or secondary structures, proteomimetics recapitulate tertiary structures. This can involve the mimicry of entire protein domains [2] or fragments thereof. [3] Proteomimetic approaches can range from entirely abiotic scaffolds [2] to specific main chain and side chain-modifications. [4] [5]