- October 2, 1996 - Flight Aeroperú 603 crashes off the coast of Lima killing all crew members and passengers on board.
- October 5, 1885 - Medical student Daniel Alcides Carrión dies of self-inflicted Carrion's disease in an experiment to cure the disease.
- October 8, 1879 - Naval officer Miguel Grau was killed in the Naval Battle of Angamos during the War of the Pacific with Chile.
- October 22, 1570 - Viceroy Francisco de Toledo started a five-year visit of the Viceroyalty of Peru during which he implemented far-reaching reforms.
- October 28, 1975 - At the South American Championship the national football team wins its second Copa América.
- October 2, 1996 - Flight Aeroperú 603 crashes off the coast of Lima killing all crew members and passengers on board.
- October 5, 1885 - Medical student Daniel Alcides Carrión dies of self-inflicted Carrion's disease in an experiment to cure the disease.
- October 8, 1879 - Naval officer Miguel Grau was killed in the Naval Battle of Angamos during the War of the Pacific with Chile.
- October 22, 1570 - Viceroy Francisco de Toledo started a five-year visit of the Viceroyalty of Peru during which he implemented far-reaching reforms.
- October 28, 1975 - At the South American Championship the national football team wins its second Copa América.