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Names | |
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IUPAC name
(2Z,6E)-2-[(3E)-4,8-Dimethylnona-3,7-dienyl]-6-methylocta-2,6-diene-1,8-diol
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Other names
18-Hydroxygeranylgeraniol; Kelnac
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Identifiers | |
3D model (
JSmol)
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KEGG | |
PubChem
CID
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UNII | |
CompTox Dashboard (
EPA)
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Properties | |
C20H34O2 | |
Molar mass | 306.490 g·mol−1 |
Pharmacology | |
Legal status |
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Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Plaunotol (18-hydroxygeranylgeraniol) is a chemical compound with the molecular formula C20H34O2. It is a diterpene that was first isolated from Croton sublyratus. [1]
Plaunotol has been identified as present in Croton sublyratus [1] and Croton stellatopilosus. [2] In plants, the compound is biosynthesized by hydroxylation of geranylgeraniol, a reaction which is catalyzed by the enzyme geranylgeraniol 18-hydroxylase. [3] A laboratory synthesis of plaunotol has been reported. [4]
Plaunotol has antibacterial activity against Helicobacter pylori, the bacteria that causes gastric ulcers. [5] In Japan, plauntool is used as a pharmaceutical drug under the trade name Kelnac for the treatment of gastritis and gastric ulcers. [6]
![]() | |
Names | |
---|---|
IUPAC name
(2Z,6E)-2-[(3E)-4,8-Dimethylnona-3,7-dienyl]-6-methylocta-2,6-diene-1,8-diol
| |
Other names
18-Hydroxygeranylgeraniol; Kelnac
| |
Identifiers | |
3D model (
JSmol)
|
|
KEGG | |
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
Properties | |
C20H34O2 | |
Molar mass | 306.490 g·mol−1 |
Pharmacology | |
Legal status |
|
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Plaunotol (18-hydroxygeranylgeraniol) is a chemical compound with the molecular formula C20H34O2. It is a diterpene that was first isolated from Croton sublyratus. [1]
Plaunotol has been identified as present in Croton sublyratus [1] and Croton stellatopilosus. [2] In plants, the compound is biosynthesized by hydroxylation of geranylgeraniol, a reaction which is catalyzed by the enzyme geranylgeraniol 18-hydroxylase. [3] A laboratory synthesis of plaunotol has been reported. [4]
Plaunotol has antibacterial activity against Helicobacter pylori, the bacteria that causes gastric ulcers. [5] In Japan, plauntool is used as a pharmaceutical drug under the trade name Kelnac for the treatment of gastritis and gastric ulcers. [6]