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Names | |
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Preferred IUPAC name
1-Hydroxy-2-methoxydibenzo[cd,f]indol-4(5H)-one | |
Other names
Aristolactam FI
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Identifiers | |
3D model (
JSmol)
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ChEBI | |
ChEMBL | |
ChemSpider | |
PubChem
CID
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CompTox Dashboard (
EPA)
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Properties | |
C16H11NO3 | |
Molar mass | 265.268 g·mol−1 |
Melting point | 313 °C (595 °F; 586 K) |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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Piperolactam A is a natural product alkaloid found in many plants and first isolated from roots of Piper longum (long pepper). As a group, such compounds are called aristolactams, and are related to aristolochic acid.
Piperolactam A was first reported in 1988 after isolation from an extract of Piper longum. [1] Many closely related natural product alkaloids are known including aristolochic acid and its lactam derivatives. [2] [3] In some reports, piperolactam A is called aristolactam FI. [4]
It has been suggested that piperolactam A and related compounds are biosynthesised from aporphine precursors. [5]
Aristolactams including piperolactam A have been the subject of chemical synthesis studies, [4] which have been reviewed. [6]
Piperolactam A and related compounds are found in Aristolochiaceae (birthwort), Annonaceae (custard apple), Piperaceae (pepper), and Saururaceae plant families. [2] [6]
![]() | |
Names | |
---|---|
Preferred IUPAC name
1-Hydroxy-2-methoxydibenzo[cd,f]indol-4(5H)-one | |
Other names
Aristolactam FI
| |
Identifiers | |
3D model (
JSmol)
|
|
ChEBI | |
ChEMBL | |
ChemSpider | |
PubChem
CID
|
|
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C16H11NO3 | |
Molar mass | 265.268 g·mol−1 |
Melting point | 313 °C (595 °F; 586 K) |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Piperolactam A is a natural product alkaloid found in many plants and first isolated from roots of Piper longum (long pepper). As a group, such compounds are called aristolactams, and are related to aristolochic acid.
Piperolactam A was first reported in 1988 after isolation from an extract of Piper longum. [1] Many closely related natural product alkaloids are known including aristolochic acid and its lactam derivatives. [2] [3] In some reports, piperolactam A is called aristolactam FI. [4]
It has been suggested that piperolactam A and related compounds are biosynthesised from aporphine precursors. [5]
Aristolactams including piperolactam A have been the subject of chemical synthesis studies, [4] which have been reviewed. [6]
Piperolactam A and related compounds are found in Aristolochiaceae (birthwort), Annonaceae (custard apple), Piperaceae (pepper), and Saururaceae plant families. [2] [6]