Paul Kraske (2 June 1851, Berg, Province of Silesia – 15 June 1930, Freiburg im Breisgau) was a German surgeon.

He studied medicine at the universities of Halle and Leipzig, receiving his doctorate at Halle in 1874. While a student, he served as a volunteer soldier in a fusilier regiment during the Franco-Prussian War. After graduation, he spent several years as an assistant to Richard von Volkmann at the surgical clinic in Halle, then from 1883 to 1919 was a professor and head of the surgical clinic at the University of Freiburg. ^{[1] [2]}

He held a particular interest in colorectal cancer, and is remembered for introducing a transsacral approach for the extirpation of cancers of the rectum ("Kraske's operation"). ^[3]

• Beiträge zur Lehre von dem Einflusse der Nerven auf die Ernährung der Gewebe, 1874 – Study on the influence of nerves involving the nutrition of tissues.
• Experimentelle Untersuchungen ueber die Regeneration der quergestreiften Muskeln, 1878 – Experimental studies on the regeneration of striated muscles.
• Die sacrale Methode der Exstirpation von Mastdarmkrebsen und die Resectio recti, 1887 – The sacral method for extirpation of rectal cancers and resection of the rectum. ^{[1] [3]}