PagetâSchrotter disease | |
---|---|
Other names | Pagetâvon Schrötter disease |
Anterior view of right upper limb and thorax | |
Specialty | Vascular surgery |
Named after |
PagetâSchroetter disease (which evolved from a venous thoracic outlet syndrome) is a form of upper extremity deep vein thrombosis (DVT), a medical condition in which blood clots form in the deep veins of the arms. These DVTs typically occur in the axillary and/or subclavian veins. [1]
The condition is relatively rare. [2] It usually presents in young and otherwise healthy patients, and also occurs more often in males than females. The syndrome also became known as "effort-induced thrombosis" in the 1960s, [3] as it has been reported to occur after vigorous activity, [4] though it can also occur due to anatomic abnormality such as clavicle impingement [5] or spontaneously. It may develop as a sequela of thoracic outlet syndrome. It is differentiated from secondary causes of upper extremity thrombosis caused by intravascular catheters. [4] PagetâSchroetter syndrome was described once for a viola player who suddenly increased practice time 10-fold, creating enough repetitive pressure against the brachiocephalic and external jugular veins to cause thrombosis. [6]
Symptoms may include sudden onset of pain, warmth, redness, blueness and swelling in the arm. Diagnosis is usually confirmed with an ultrasound. [7] These DVTs have the potential to cause a pulmonary embolism. [8]
Duplex ultrasonography MR Venography[ citation needed]
Prevention of PagetâSchroetter disease can be accomplished by gradual increases in activity and by avoiding strenuous upper extremity activity. [9]
The traditional treatment for thrombosis is the same as for a lower extremity DVT, and involves systemic anticoagulation to prevent a pulmonary embolus. [10] Some have also recommended thrombolysis with catheter directed alteplase or mechanical thrombectomy with a large bore catheter and manual aspiration providing definitive intervention with an endovascular approach. [11] If there is thoracic outlet syndrome or other anatomical cause then surgery can be considered to correct the underlying defect. [12]
The condition is named after two men. James Paget [13] first proposed the idea of venous thrombosis causing upper extremity pain and swelling, [14] and Leopold von Schrötter later linked the clinical syndrome to thrombosis of the axillary and subclavian veins. [15]
PagetâSchrotter disease | |
---|---|
Other names | Pagetâvon Schrötter disease |
Anterior view of right upper limb and thorax | |
Specialty | Vascular surgery |
Named after |
PagetâSchroetter disease (which evolved from a venous thoracic outlet syndrome) is a form of upper extremity deep vein thrombosis (DVT), a medical condition in which blood clots form in the deep veins of the arms. These DVTs typically occur in the axillary and/or subclavian veins. [1]
The condition is relatively rare. [2] It usually presents in young and otherwise healthy patients, and also occurs more often in males than females. The syndrome also became known as "effort-induced thrombosis" in the 1960s, [3] as it has been reported to occur after vigorous activity, [4] though it can also occur due to anatomic abnormality such as clavicle impingement [5] or spontaneously. It may develop as a sequela of thoracic outlet syndrome. It is differentiated from secondary causes of upper extremity thrombosis caused by intravascular catheters. [4] PagetâSchroetter syndrome was described once for a viola player who suddenly increased practice time 10-fold, creating enough repetitive pressure against the brachiocephalic and external jugular veins to cause thrombosis. [6]
Symptoms may include sudden onset of pain, warmth, redness, blueness and swelling in the arm. Diagnosis is usually confirmed with an ultrasound. [7] These DVTs have the potential to cause a pulmonary embolism. [8]
Duplex ultrasonography MR Venography[ citation needed]
Prevention of PagetâSchroetter disease can be accomplished by gradual increases in activity and by avoiding strenuous upper extremity activity. [9]
The traditional treatment for thrombosis is the same as for a lower extremity DVT, and involves systemic anticoagulation to prevent a pulmonary embolus. [10] Some have also recommended thrombolysis with catheter directed alteplase or mechanical thrombectomy with a large bore catheter and manual aspiration providing definitive intervention with an endovascular approach. [11] If there is thoracic outlet syndrome or other anatomical cause then surgery can be considered to correct the underlying defect. [12]
The condition is named after two men. James Paget [13] first proposed the idea of venous thrombosis causing upper extremity pain and swelling, [14] and Leopold von Schrötter later linked the clinical syndrome to thrombosis of the axillary and subclavian veins. [15]