Protease, serine, 3 is a
protein that in humans is encoded by the PRSS3
gene.[5]
Function
This gene encodes a
trypsinogen, which is a member of the
trypsin family of
serine proteases. This enzyme is expressed in the
brain and
pancreas and is resistant to common
trypsin inhibitors. It is active on
peptide linkages involving the carboxyl group of
lysine or
arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene.
Masson E, Le Maréchal C, Chen JM, Férec C (August 2008). "Absence of mesotrypsinogen gene (PRSS3) copy number variations in patients with chronic pancreatitis". Pancreas. 37 (2): 227–8.
doi:
10.1097/MPA.0b013e3181654b6a.
PMID18665091.
Protease, serine, 3 is a
protein that in humans is encoded by the PRSS3
gene.[5]
Function
This gene encodes a
trypsinogen, which is a member of the
trypsin family of
serine proteases. This enzyme is expressed in the
brain and
pancreas and is resistant to common
trypsin inhibitors. It is active on
peptide linkages involving the carboxyl group of
lysine or
arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene.
Masson E, Le Maréchal C, Chen JM, Férec C (August 2008). "Absence of mesotrypsinogen gene (PRSS3) copy number variations in patients with chronic pancreatitis". Pancreas. 37 (2): 227–8.
doi:
10.1097/MPA.0b013e3181654b6a.
PMID18665091.