PRINS (psoriasis associated RNA induced by stress) is a
long non-coding RNA. Its expression is induced by stress, and it may have a protective role in
cells exposed to stress. It is over-expressed in the skin of patients with
psoriasis.[2] It regulates
G1P3, a
gene encoding a
protein with anti-
apoptotic effects in
keratinocytes. Overexpression of PRINS may contribute to psoriasis via the down-regulation of G1P3.[3]
^Szegedi K, Sonkoly E, Nagy N, et al. (March 2010). "The anti-apoptotic protein G1P3 is overexpressed in psoriasis and regulated by the non-coding RNA, PRINS". Exp. Dermatol. 19 (3): 269–278.
doi:
10.1111/j.1600-0625.2010.01066.x.
PMID20377629.
S2CID205822988.
PRINS (psoriasis associated RNA induced by stress) is a
long non-coding RNA. Its expression is induced by stress, and it may have a protective role in
cells exposed to stress. It is over-expressed in the skin of patients with
psoriasis.[2] It regulates
G1P3, a
gene encoding a
protein with anti-
apoptotic effects in
keratinocytes. Overexpression of PRINS may contribute to psoriasis via the down-regulation of G1P3.[3]
^Szegedi K, Sonkoly E, Nagy N, et al. (March 2010). "The anti-apoptotic protein G1P3 is overexpressed in psoriasis and regulated by the non-coding RNA, PRINS". Exp. Dermatol. 19 (3): 269–278.
doi:
10.1111/j.1600-0625.2010.01066.x.
PMID20377629.
S2CID205822988.