PPP1CC - Encyclopedia Information

From Wikipedia, the free encyclopedia

PPP1CC

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1IT6, 1JK7, 1U32, 2BCD, 2BDX, 4UT2, 4UT3

Identifiers

PPP1CC, PP-1G, PP1C, PPP1G, protein phosphatase 1 catalytic subunit gamma

External IDs

OMIM: 176914 MGI: 3647492 HomoloGene: 100608 GeneCards: PPP1CC

Gene location ( Human)

Chr.	Chromosome 12 (human)^[1]

Band	12q24.11	Start	110,719,680 bp^[1]
Band	12q24.11	End	110,742,939 bp^[1]

Gene location ( Mouse)

Chr.	Chromosome 5 (mouse)^[2]

Band	7\|7 F2	Start	122,158,278 bp^[2]
Band	7\|7 F2	End	122,175,273 bp^[2]

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

jejunal mucosa

right ventricle

parotid gland

secondary oocyte

superficial temporal artery

duodenum

sperm

oral cavity

germinal epithelium

tibia

Top expressed in

spermatocyte

spermatid

olfactory bulb

ganglionic eminence

thymus

cerebellar cortex

bone marrow

ovary

uterus

superior frontal gyrus

More reference expression data


More reference expression data

Gene ontology
Molecular function	phosphoprotein phosphatase activity protein domain specific binding protein N-terminus binding phosphatase activity protein-containing complex binding protein serine/threonine phosphatase activity metal ion binding protein phosphatase 1 binding protein C-terminus binding protein binding protein phosphatase binding hydrolase activity protein kinase binding lamin binding RNA binding
Cellular component	cytoplasm cytosol nuclear speck focal adhesion dendritic spine chromosome nucleoplasm mitochondrial outer membrane midbody PTW/PP1 phosphatase complex nucleolus mitochondrion cleavage furrow chromosome, centromeric region nucleus kinetochore protein phosphatase type 1 complex protein-containing complex presynapse postsynapse glutamatergic synapse
Biological process	regulation of nucleocytoplasmic transport rhythmic process protein dephosphorylation circadian regulation of gene expression cell division regulation of circadian rhythm neuron differentiation glycogen metabolic process cell cycle entrainment of circadian clock by photoperiod sister chromatid cohesion carbohydrate metabolic process positive regulation of glial cell proliferation
Sources: Amigo / QuickGO

Species

Human

Mouse


5501


434233


ENSG00000186298


ENSMUSG00000004455


P36873


P63087

RefSeq (mRNA)


NM_001244974 NM_002710


XM_006508415

RefSeq (protein)


NP_001231903 NP_002701


NP_038664

Location (UCSC)

Chr 12: 110.72 – 110.74 Mb

Chr 5: 122.16 – 122.18 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

Serine/threonine-protein phosphatase PP1-gamma catalytic subunit is an enzyme that in humans is encoded by the PPP1CC gene.^[5]

Interactions

PPP1CC has been shown to interact with PPP1R15A,^[6]^[7] SMARCB1,^[6] TLX1^[8] and PPP1R9B.^[9]^[10]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000186298 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000004455 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: PPP1CC Protein phosphatase 1, catalytic subunit, gamma isoform".
^ ^a ^b Wu DY, Tkachuck Douglas C, Roberson Rachel S, Schubach William H (Aug 2002). "The human SNF5/INI1 protein facilitates the function of the growth arrest and DNA damage-inducible protein (GADD34) and modulates GADD34-bound protein phosphatase-1 activity". J. Biol. Chem. 277 (31). United States: 27706–15. doi: 10.1074/jbc.M200955200. ISSN 0021-9258. PMID 12016208.
^ Connor JH, Weiser D C, Li S, Hallenbeck J M, Shenolikar S (Oct 2001). "Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1". Mol. Cell. Biol. 21 (20). United States: 6841–50. doi: 10.1128/MCB.21.20.6841-6850.2001. ISSN 0270-7306. PMC 99861. PMID 11564868.
^ Kawabe T, Muslin A J, Korsmeyer S J (Jan 1997). "HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint". Nature. 385 (6615). ENGLAND: 454–8. Bibcode: 1997Natur.385..454K. doi: 10.1038/385454a0. ISSN 0028-0836. PMID 9009195. S2CID 608633.
^ Hsieh-Wilson LC, Allen P B, Watanabe T, Nairn A C, Greengard P (Apr 1999). "Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1". Biochemistry. 38 (14). UNITED STATES: 4365–73. doi: 10.1021/bi982900m. ISSN 0006-2960. PMID 10194355.
^ Smith FD, Oxford G S, Milgram S L (Jul 1999). "Association of the D2 dopamine receptor third cytoplasmic loop with spinophilin, a protein phosphatase-1-interacting protein". J. Biol. Chem. 274 (28). UNITED STATES: 19894–900. doi: 10.1074/jbc.274.28.19894. ISSN 0021-9258. PMID 10391935.

Further reading

Van Eynde A, Wera S, Beullens M, et al. (1996). "Molecular cloning of NIPP-1, a nuclear inhibitor of protein phosphatase-1, reveals homology with polypeptides involved in RNA processing". J. Biol. Chem. 270 (47): 28068–74. doi: 10.1074/jbc.270.47.28068. PMID 7499293.
Egloff MP, Cohen PT, Reinemer P, Barford D (1996). "Crystal structure of the catalytic subunit of human protein phosphatase 1 and its complex with tungstate". J. Mol. Biol. 254 (5): 942–59. doi: 10.1006/jmbi.1995.0667. PMID 7500362.
MacKintosh RW, Dalby KN, Campbell DG, et al. (1995). "The cyanobacterial toxin microcystin binds covalently to cysteine-273 on protein phosphatase 1". FEBS Lett. 371 (3): 236–40. doi: 10.1016/0014-5793(95)00888-G. PMID 7556599. S2CID 42021604.
Norman SA, Mott DM (1994). "Molecular cloning and chromosomal localization of a human skeletal muscle PP-1 gamma 1 cDNA". Mamm. Genome. 5 (1): 41–5. doi: 10.1007/BF00360567. PMID 8111128. S2CID 21566111.
Barker HM, Craig SP, Spurr NK, Cohen PT (1993). "Sequence of human protein serine/threonine phosphatase 1 gamma and localization of the gene (PPP1CC) encoding it to chromosome bands 12q24.1-q24.2". Biochim. Biophys. Acta. 1178 (2): 228–33. doi: 10.1016/0167-4889(93)90014-G. PMID 8394140.
Helps NR, Barker HM, Elledge SJ, Cohen PT (1996). "Protein phosphatase 1 interacts with p53BP2, a protein which binds to the tumour suppressor p53". FEBS Lett. 377 (3): 295–300. doi: 10.1016/0014-5793(95)01347-4. PMID 8549741. S2CID 3010008.
Saadat M, Nomoto K, Mizuno Y, et al. (1996). "Assignment of the gene encoding type 1 gamma protein phosphatase catalytic subunit (PPP1CC) on human, rat, and mouse chromosomes". Jpn. J. Hum. Genet. 41 (1): 159–65. doi: 10.1007/BF01892623. PMID 8914631.
Armstrong CG, Browne GJ, Cohen P, Cohen PT (1998). "PPP1R6, a novel member of the family of glycogen-targeting subunits of protein phosphatase 1". FEBS Lett. 418 (1–2): 210–4. doi: 10.1016/S0014-5793(97)01385-9. PMID 9414128. S2CID 21169749.
Andreassen PR, Lacroix FB, Villa-Moruzzi E, Margolis RL (1998). "Differential subcellular localization of protein phosphatase-1 alpha, gamma1, and delta isoforms during both interphase and mitosis in mammalian cells". J. Cell Biol. 141 (5): 1207–15. doi: 10.1083/jcb.141.5.1207. PMC 2137188. PMID 9606212.
Ajuh PM, Browne GJ, Hawkes NA, et al. (2000). "Association of a protein phosphatase 1 activity with the human factor C1 (HCF) complex". Nucleic Acids Res. 28 (3): 678–86. doi: 10.1093/nar/28.3.678. PMC 102561. PMID 10637318.
Yang J, Hurley TD, DePaoli-Roach AA (2000). "Interaction of inhibitor-2 with the catalytic subunit of type 1 protein phosphatase. Identification of a sequence analogous to the consensus type 1 protein phosphatase-binding motif". J. Biol. Chem. 275 (30): 22635–44. doi: 10.1074/jbc.M003082200. PMID 10807923.
Katayama H, Zhou H, Li Q, et al. (2002). "Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycle". J. Biol. Chem. 276 (49): 46219–24. doi: 10.1074/jbc.M107540200. PMID 11551964.
Patel KG, Liu C, Cameron PL, Cameron RS (2001). "Myr 8, a novel unconventional myosin expressed during brain development associates with the protein phosphatase catalytic subunits 1alpha and 1gamma1". J. Neurosci. 21 (20): 7954–68. doi: 10.1523/JNEUROSCI.21-20-07954.2001. PMC 6763852. PMID 11588169.
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode: 2002CBio...12....1A. doi: 10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
Jones JA, Hannun YA (2002). "Tight binding inhibition of protein phosphatase-1 by phosphatidic acid. Specificity of inhibition by the phospholipid". J. Biol. Chem. 277 (18): 15530–8. doi: 10.1074/jbc.M111555200. PMID 11856740.
Wu DY, Tkachuck DC, Roberson RS, Schubach WH (2002). "The human SNF5/INI1 protein facilitates the function of the growth arrest and DNA damage-inducible protein (GADD34) and modulates GADD34-bound protein phosphatase-1 activity". J. Biol. Chem. 277 (31): 27706–15. doi: 10.1074/jbc.M200955200. PMID 12016208.
Bharucha DC, Zhou M, Nekhai S, et al. (2002). "A protein phosphatase from human T cells augments tat transactivation of the human immunodeficiency virus type 1 long-terminal repeat". Virology. 296 (1): 6–16. doi: 10.1006/viro.2002.1438. PMID 12036313.
Tan SL, Tareen SU, Melville MW, et al. (2002). "The direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formation". J. Biol. Chem. 277 (39): 36109–17. doi: 10.1074/jbc.M205109200. PMID 12138106.
Eto M, Elliott E, Prickett TD, Brautigan DL (2003). "Inhibitor-2 regulates protein phosphatase-1 complexed with NimA-related kinase to induce centrosome separation". J. Biol. Chem. 277 (46): 44013–20. doi: 10.1074/jbc.M208035200. PMID 12221103.
Ceulemans H, Vulsteke V, De Maeyer M, et al. (2003). "Binding of the concave surface of the Sds22 superhelix to the alpha 4/alpha 5/alpha 6-triangle of protein phosphatase-1". J. Biol. Chem. 277 (49): 47331–7. doi: 10.1074/jbc.M206838200. PMID 12226088.

PDB gallery

1fjm: PROTEIN SERINE/THREONINE PHOSPHATASE-1 (ALPHA ISOFORM, TYPE I) COMPLEXED WITH MICROCYSTIN-LR TOXIN
1it6: CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CALYCULIN A AND THE CATALYTIC SUBUNIT OF PROTEIN PHOSPHATASE 1
1jk7: CRYSTAL STRUCTURE OF THE TUMOR-PROMOTER OKADAIC ACID BOUND TO PROTEIN PHOSPHATASE-1
1u32: Crystal structure of a Protein Phosphatase-1: Calcineurin Hybrid Bound to Okadaic Acid
2bcd: X-ray crystal structure of Protein Phosphatase-1 with the marine toxin motuporin bound
2bdx: X-ray Crystal Structure of dihydromicrocystin-LA bound to Protein Phosphatase-1

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it.

Retrieved from " https://en.wikipedia.org/?title=PPP1CC&oldid=1218124492"

Hidden categories:

From Wikipedia, the free encyclopedia

PPP1CC

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1IT6, 1JK7, 1U32, 2BCD, 2BDX, 4UT2, 4UT3

Identifiers

PPP1CC, PP-1G, PP1C, PPP1G, protein phosphatase 1 catalytic subunit gamma

External IDs

OMIM: 176914 MGI: 3647492 HomoloGene: 100608 GeneCards: PPP1CC

Gene location ( Human)

Chr.	Chromosome 12 (human)^[1]

Band	12q24.11	Start	110,719,680 bp^[1]
Band	12q24.11	End	110,742,939 bp^[1]

Gene location ( Mouse)

Chr.	Chromosome 5 (mouse)^[2]

Band	7\|7 F2	Start	122,158,278 bp^[2]
Band	7\|7 F2	End	122,175,273 bp^[2]

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

jejunal mucosa

right ventricle

parotid gland

secondary oocyte

superficial temporal artery

duodenum

sperm

oral cavity

germinal epithelium

tibia

Top expressed in

spermatocyte

spermatid

olfactory bulb

ganglionic eminence

thymus

cerebellar cortex

bone marrow

ovary

uterus

superior frontal gyrus

More reference expression data


More reference expression data

Gene ontology
Molecular function	phosphoprotein phosphatase activity protein domain specific binding protein N-terminus binding phosphatase activity protein-containing complex binding protein serine/threonine phosphatase activity metal ion binding protein phosphatase 1 binding protein C-terminus binding protein binding protein phosphatase binding hydrolase activity protein kinase binding lamin binding RNA binding
Cellular component	cytoplasm cytosol nuclear speck focal adhesion dendritic spine chromosome nucleoplasm mitochondrial outer membrane midbody PTW/PP1 phosphatase complex nucleolus mitochondrion cleavage furrow chromosome, centromeric region nucleus kinetochore protein phosphatase type 1 complex protein-containing complex presynapse postsynapse glutamatergic synapse
Biological process	regulation of nucleocytoplasmic transport rhythmic process protein dephosphorylation circadian regulation of gene expression cell division regulation of circadian rhythm neuron differentiation glycogen metabolic process cell cycle entrainment of circadian clock by photoperiod sister chromatid cohesion carbohydrate metabolic process positive regulation of glial cell proliferation
Sources: Amigo / QuickGO

Species

Human

Mouse


5501


434233


ENSG00000186298


ENSMUSG00000004455


P36873


P63087

RefSeq (mRNA)


NM_001244974 NM_002710


XM_006508415

RefSeq (protein)


NP_001231903 NP_002701


NP_038664

Location (UCSC)

Chr 12: 110.72 – 110.74 Mb

Chr 5: 122.16 – 122.18 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

Serine/threonine-protein phosphatase PP1-gamma catalytic subunit is an enzyme that in humans is encoded by the PPP1CC gene.^[5]

Interactions

PPP1CC has been shown to interact with PPP1R15A,^[6]^[7] SMARCB1,^[6] TLX1^[8] and PPP1R9B.^[9]^[10]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000186298 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000004455 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: PPP1CC Protein phosphatase 1, catalytic subunit, gamma isoform".
^ ^a ^b Wu DY, Tkachuck Douglas C, Roberson Rachel S, Schubach William H (Aug 2002). "The human SNF5/INI1 protein facilitates the function of the growth arrest and DNA damage-inducible protein (GADD34) and modulates GADD34-bound protein phosphatase-1 activity". J. Biol. Chem. 277 (31). United States: 27706–15. doi: 10.1074/jbc.M200955200. ISSN 0021-9258. PMID 12016208.
^ Connor JH, Weiser D C, Li S, Hallenbeck J M, Shenolikar S (Oct 2001). "Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1". Mol. Cell. Biol. 21 (20). United States: 6841–50. doi: 10.1128/MCB.21.20.6841-6850.2001. ISSN 0270-7306. PMC 99861. PMID 11564868.
^ Kawabe T, Muslin A J, Korsmeyer S J (Jan 1997). "HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint". Nature. 385 (6615). ENGLAND: 454–8. Bibcode: 1997Natur.385..454K. doi: 10.1038/385454a0. ISSN 0028-0836. PMID 9009195. S2CID 608633.
^ Hsieh-Wilson LC, Allen P B, Watanabe T, Nairn A C, Greengard P (Apr 1999). "Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1". Biochemistry. 38 (14). UNITED STATES: 4365–73. doi: 10.1021/bi982900m. ISSN 0006-2960. PMID 10194355.
^ Smith FD, Oxford G S, Milgram S L (Jul 1999). "Association of the D2 dopamine receptor third cytoplasmic loop with spinophilin, a protein phosphatase-1-interacting protein". J. Biol. Chem. 274 (28). UNITED STATES: 19894–900. doi: 10.1074/jbc.274.28.19894. ISSN 0021-9258. PMID 10391935.

Further reading

Van Eynde A, Wera S, Beullens M, et al. (1996). "Molecular cloning of NIPP-1, a nuclear inhibitor of protein phosphatase-1, reveals homology with polypeptides involved in RNA processing". J. Biol. Chem. 270 (47): 28068–74. doi: 10.1074/jbc.270.47.28068. PMID 7499293.
Egloff MP, Cohen PT, Reinemer P, Barford D (1996). "Crystal structure of the catalytic subunit of human protein phosphatase 1 and its complex with tungstate". J. Mol. Biol. 254 (5): 942–59. doi: 10.1006/jmbi.1995.0667. PMID 7500362.
MacKintosh RW, Dalby KN, Campbell DG, et al. (1995). "The cyanobacterial toxin microcystin binds covalently to cysteine-273 on protein phosphatase 1". FEBS Lett. 371 (3): 236–40. doi: 10.1016/0014-5793(95)00888-G. PMID 7556599. S2CID 42021604.
Norman SA, Mott DM (1994). "Molecular cloning and chromosomal localization of a human skeletal muscle PP-1 gamma 1 cDNA". Mamm. Genome. 5 (1): 41–5. doi: 10.1007/BF00360567. PMID 8111128. S2CID 21566111.
Barker HM, Craig SP, Spurr NK, Cohen PT (1993). "Sequence of human protein serine/threonine phosphatase 1 gamma and localization of the gene (PPP1CC) encoding it to chromosome bands 12q24.1-q24.2". Biochim. Biophys. Acta. 1178 (2): 228–33. doi: 10.1016/0167-4889(93)90014-G. PMID 8394140.
Helps NR, Barker HM, Elledge SJ, Cohen PT (1996). "Protein phosphatase 1 interacts with p53BP2, a protein which binds to the tumour suppressor p53". FEBS Lett. 377 (3): 295–300. doi: 10.1016/0014-5793(95)01347-4. PMID 8549741. S2CID 3010008.
Saadat M, Nomoto K, Mizuno Y, et al. (1996). "Assignment of the gene encoding type 1 gamma protein phosphatase catalytic subunit (PPP1CC) on human, rat, and mouse chromosomes". Jpn. J. Hum. Genet. 41 (1): 159–65. doi: 10.1007/BF01892623. PMID 8914631.
Armstrong CG, Browne GJ, Cohen P, Cohen PT (1998). "PPP1R6, a novel member of the family of glycogen-targeting subunits of protein phosphatase 1". FEBS Lett. 418 (1–2): 210–4. doi: 10.1016/S0014-5793(97)01385-9. PMID 9414128. S2CID 21169749.
Andreassen PR, Lacroix FB, Villa-Moruzzi E, Margolis RL (1998). "Differential subcellular localization of protein phosphatase-1 alpha, gamma1, and delta isoforms during both interphase and mitosis in mammalian cells". J. Cell Biol. 141 (5): 1207–15. doi: 10.1083/jcb.141.5.1207. PMC 2137188. PMID 9606212.
Ajuh PM, Browne GJ, Hawkes NA, et al. (2000). "Association of a protein phosphatase 1 activity with the human factor C1 (HCF) complex". Nucleic Acids Res. 28 (3): 678–86. doi: 10.1093/nar/28.3.678. PMC 102561. PMID 10637318.
Yang J, Hurley TD, DePaoli-Roach AA (2000). "Interaction of inhibitor-2 with the catalytic subunit of type 1 protein phosphatase. Identification of a sequence analogous to the consensus type 1 protein phosphatase-binding motif". J. Biol. Chem. 275 (30): 22635–44. doi: 10.1074/jbc.M003082200. PMID 10807923.
Katayama H, Zhou H, Li Q, et al. (2002). "Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycle". J. Biol. Chem. 276 (49): 46219–24. doi: 10.1074/jbc.M107540200. PMID 11551964.
Patel KG, Liu C, Cameron PL, Cameron RS (2001). "Myr 8, a novel unconventional myosin expressed during brain development associates with the protein phosphatase catalytic subunits 1alpha and 1gamma1". J. Neurosci. 21 (20): 7954–68. doi: 10.1523/JNEUROSCI.21-20-07954.2001. PMC 6763852. PMID 11588169.
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode: 2002CBio...12....1A. doi: 10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
Jones JA, Hannun YA (2002). "Tight binding inhibition of protein phosphatase-1 by phosphatidic acid. Specificity of inhibition by the phospholipid". J. Biol. Chem. 277 (18): 15530–8. doi: 10.1074/jbc.M111555200. PMID 11856740.
Wu DY, Tkachuck DC, Roberson RS, Schubach WH (2002). "The human SNF5/INI1 protein facilitates the function of the growth arrest and DNA damage-inducible protein (GADD34) and modulates GADD34-bound protein phosphatase-1 activity". J. Biol. Chem. 277 (31): 27706–15. doi: 10.1074/jbc.M200955200. PMID 12016208.
Bharucha DC, Zhou M, Nekhai S, et al. (2002). "A protein phosphatase from human T cells augments tat transactivation of the human immunodeficiency virus type 1 long-terminal repeat". Virology. 296 (1): 6–16. doi: 10.1006/viro.2002.1438. PMID 12036313.
Tan SL, Tareen SU, Melville MW, et al. (2002). "The direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formation". J. Biol. Chem. 277 (39): 36109–17. doi: 10.1074/jbc.M205109200. PMID 12138106.
Eto M, Elliott E, Prickett TD, Brautigan DL (2003). "Inhibitor-2 regulates protein phosphatase-1 complexed with NimA-related kinase to induce centrosome separation". J. Biol. Chem. 277 (46): 44013–20. doi: 10.1074/jbc.M208035200. PMID 12221103.
Ceulemans H, Vulsteke V, De Maeyer M, et al. (2003). "Binding of the concave surface of the Sds22 superhelix to the alpha 4/alpha 5/alpha 6-triangle of protein phosphatase-1". J. Biol. Chem. 277 (49): 47331–7. doi: 10.1074/jbc.M206838200. PMID 12226088.

PDB gallery

1fjm: PROTEIN SERINE/THREONINE PHOSPHATASE-1 (ALPHA ISOFORM, TYPE I) COMPLEXED WITH MICROCYSTIN-LR TOXIN
1it6: CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CALYCULIN A AND THE CATALYTIC SUBUNIT OF PROTEIN PHOSPHATASE 1
1jk7: CRYSTAL STRUCTURE OF THE TUMOR-PROMOTER OKADAIC ACID BOUND TO PROTEIN PHOSPHATASE-1
1u32: Crystal structure of a Protein Phosphatase-1: Calcineurin Hybrid Bound to Okadaic Acid
2bcd: X-ray crystal structure of Protein Phosphatase-1 with the marine toxin motuporin bound
2bdx: X-ray Crystal Structure of dihydromicrocystin-LA bound to Protein Phosphatase-1

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it.

Retrieved from " https://en.wikipedia.org/?title=PPP1CC&oldid=1218124492"

Hidden categories:

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