(Redirected from
PLXNA1)
Plexin-A1 is a protein that in humans is encoded by the PLXNA1 gene. [5] [6]
Interactions
Plexin A1 has been shown to interact with AKT1. [7]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000114554 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030084 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Maestrini E, Tamagnone L, Longati P, Cremona O, Gulisano M, Bione S, Tamanini F, Neel BG, Toniolo D, Comoglio PM (Mar 1996). "A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor". Proc Natl Acad Sci U S A. 93 (2): 674–8. Bibcode: 1996PNAS...93..674M. doi: 10.1073/pnas.93.2.674. PMC 40111. PMID 8570614.
- ^ "Entrez Gene: PLXNA1 plexin A1".
- ^ Turner, Laura J; Nicholls Sarah; Hall Alan (Aug 2004). "The activity of the plexin-A1 receptor is regulated by Rac". J. Biol. Chem. 279 (32). United States: 33199–205. doi: 10.1074/jbc.M402943200. ISSN 0021-9258. PMID 15187088.
Further reading
- Takahashi T, Fournier A, Nakamura F, et al. (1999). "Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors". Cell. 99 (1): 59–69. doi: 10.1016/S0092-8674(00)80062-8. PMID 10520994. S2CID 18167425.
- Tamagnone L, Artigiani S, Chen H, et al. (1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates". Cell. 99 (1): 71–80. doi: 10.1016/S0092-8674(00)80063-X. PMID 10520995. S2CID 17386412.
- Rohm B, Rahim B, Kleiber B, et al. (2001). "The semaphorin 3A receptor may directly regulate the activity of small GTPases". FEBS Lett. 486 (1): 68–72. doi: 10.1016/S0014-5793(00)02240-7. PMID 11108845. S2CID 7914214.
- Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi: 10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
- Takahashi T, Strittmatter SM (2001). "Plexina1 autoinhibition by the plexin sema domain". Neuron. 29 (2): 429–39. doi: 10.1016/S0896-6273(01)00216-1. PMID 11239433. S2CID 2487482.
- Zanata SM, Hovatta I, Rohm B, Püschel AW (2002). "Antagonistic effects of Rnd1 and RhoD GTPases regulate receptor activity in Semaphorin 3A-induced cytoskeletal collapse". J. Neurosci. 22 (2): 471–7. doi: 10.1523/JNEUROSCI.22-02-00471.2002. PMC 6758682. PMID 11784792.
- Mitsui N, Inatome R, Takahashi S, et al. (2002). "Involvement of Fes/Fps tyrosine kinase in semaphorin3A signaling". EMBO J. 21 (13): 3274–85. doi: 10.1093/emboj/cdf328. PMC 125392. PMID 12093729.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode: 2002PNAS...9916899M. doi: 10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Usui H, Taniguchi M, Yokomizo T, Shimizu T (2003). "Plexin-A1 and plexin-B1 specifically interact at their cytoplasmic domains". Biochem. Biophys. Res. Commun. 300 (4): 927–31. doi: 10.1016/S0006-291X(02)02966-2. PMID 12559962.
- Bachelder RE, Lipscomb EA, Lin X, et al. (2003). "Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells". Cancer Res. 63 (17): 5230–3. PMID 14500350.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285. PMID 14702039.
- Toyofuku T, Zhang H, Kumanogoh A, et al. (2004). "Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2". Genes Dev. 18 (4): 435–47. doi: 10.1101/gad.1167304. PMC 359397. PMID 14977921.
- Turner LJ, Nicholls S, Hall A (2004). "The activity of the plexin-A1 receptor is regulated by Rac". J. Biol. Chem. 279 (32): 33199–205. doi: 10.1074/jbc.M402943200. PMID 15187088.
- Muzny DM, Scherer SE, Kaul R, et al. (2006). "The DNA sequence, annotation and analysis of human chromosome 3". Nature. 440 (7088): 1194–8. Bibcode: 2006Natur.440.1194M. doi: 10.1038/nature04728. PMID 16641997.
 | This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it. |
(Redirected from
PLXNA1)
| PLXNA1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | PLXNA1, NOV, NOVP, PLEXIN-A1, PLXN1, Plexin A1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 601055; MGI: 107685; HomoloGene: 56426; GeneCards: PLXNA1; OMA: PLXNA1 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
Plexin-A1 is a protein that in humans is encoded by the PLXNA1 gene. [5] [6]
Interactions
Plexin A1 has been shown to interact with AKT1. [7]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000114554 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030084 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Maestrini E, Tamagnone L, Longati P, Cremona O, Gulisano M, Bione S, Tamanini F, Neel BG, Toniolo D, Comoglio PM (Mar 1996). "A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor". Proc Natl Acad Sci U S A. 93 (2): 674–8. Bibcode: 1996PNAS...93..674M. doi: 10.1073/pnas.93.2.674. PMC 40111. PMID 8570614.
- ^ "Entrez Gene: PLXNA1 plexin A1".
- ^ Turner, Laura J; Nicholls Sarah; Hall Alan (Aug 2004). "The activity of the plexin-A1 receptor is regulated by Rac". J. Biol. Chem. 279 (32). United States: 33199–205. doi: 10.1074/jbc.M402943200. ISSN 0021-9258. PMID 15187088.
Further reading
- Takahashi T, Fournier A, Nakamura F, et al. (1999). "Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors". Cell. 99 (1): 59–69. doi: 10.1016/S0092-8674(00)80062-8. PMID 10520994. S2CID 18167425.
- Tamagnone L, Artigiani S, Chen H, et al. (1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates". Cell. 99 (1): 71–80. doi: 10.1016/S0092-8674(00)80063-X. PMID 10520995. S2CID 17386412.
- Rohm B, Rahim B, Kleiber B, et al. (2001). "The semaphorin 3A receptor may directly regulate the activity of small GTPases". FEBS Lett. 486 (1): 68–72. doi: 10.1016/S0014-5793(00)02240-7. PMID 11108845. S2CID 7914214.
- Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi: 10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
- Takahashi T, Strittmatter SM (2001). "Plexina1 autoinhibition by the plexin sema domain". Neuron. 29 (2): 429–39. doi: 10.1016/S0896-6273(01)00216-1. PMID 11239433. S2CID 2487482.
- Zanata SM, Hovatta I, Rohm B, Püschel AW (2002). "Antagonistic effects of Rnd1 and RhoD GTPases regulate receptor activity in Semaphorin 3A-induced cytoskeletal collapse". J. Neurosci. 22 (2): 471–7. doi: 10.1523/JNEUROSCI.22-02-00471.2002. PMC 6758682. PMID 11784792.
- Mitsui N, Inatome R, Takahashi S, et al. (2002). "Involvement of Fes/Fps tyrosine kinase in semaphorin3A signaling". EMBO J. 21 (13): 3274–85. doi: 10.1093/emboj/cdf328. PMC 125392. PMID 12093729.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode: 2002PNAS...9916899M. doi: 10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Usui H, Taniguchi M, Yokomizo T, Shimizu T (2003). "Plexin-A1 and plexin-B1 specifically interact at their cytoplasmic domains". Biochem. Biophys. Res. Commun. 300 (4): 927–31. doi: 10.1016/S0006-291X(02)02966-2. PMID 12559962.
- Bachelder RE, Lipscomb EA, Lin X, et al. (2003). "Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells". Cancer Res. 63 (17): 5230–3. PMID 14500350.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285. PMID 14702039.
- Toyofuku T, Zhang H, Kumanogoh A, et al. (2004). "Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2". Genes Dev. 18 (4): 435–47. doi: 10.1101/gad.1167304. PMC 359397. PMID 14977921.
- Turner LJ, Nicholls S, Hall A (2004). "The activity of the plexin-A1 receptor is regulated by Rac". J. Biol. Chem. 279 (32): 33199–205. doi: 10.1074/jbc.M402943200. PMID 15187088.
- Muzny DM, Scherer SE, Kaul R, et al. (2006). "The DNA sequence, annotation and analysis of human chromosome 3". Nature. 440 (7088): 1194–8. Bibcode: 2006Natur.440.1194M. doi: 10.1038/nature04728. PMID 16641997.
|
| This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it. |