GPI transamidase component PIG-S is an
enzyme that in humans is encoded by the PIGSgene.[5]
This gene encodes a protein that is involved in GPI-anchor
biosynthesis.
The
glycosylphosphatidylinositol (GPI) anchor is a
glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes an essential component of the multisubunit enzyme, GPI
transamidase. GPI transamidase mediates GPI anchoring in the
endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins.[5]
GPI transamidase component PIG-S is an
enzyme that in humans is encoded by the PIGSgene.[5]
This gene encodes a protein that is involved in GPI-anchor
biosynthesis.
The
glycosylphosphatidylinositol (GPI) anchor is a
glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes an essential component of the multisubunit enzyme, GPI
transamidase. GPI transamidase mediates GPI anchoring in the
endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins.[5]