From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Prohibitin-2 is a
protein that in humans is encoded by the PHB2
gene .
[5]
[6]
[7]
Interactions
PHB2 has been shown to
interact with
PTMA .
[8]
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000215021 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000004264 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Coates PJ, Nenutil R, McGregor A, Picksley SM, Crouch DH, Hall PA, Wright EG (Apr 2001). "Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence". Exp Cell Res . 265 (2): 262–73.
doi :
10.1006/excr.2001.5166 .
PMID
11302691 .
^ Coates PJ, Jamieson DJ, Smart K, Prescott AR, Hall PA (Oct 1997).
"The prohibitin family of mitochondrial proteins regulate replicative lifespan" . Curr Biol . 7 (8): 607–10.
Bibcode :
1997CBio....7..607C .
doi :
10.1016/S0960-9822(06)00261-2 .
PMID
9259555 .
S2CID
7153605 .
^
"Entrez Gene: PHB2 prohibitin 2" .
^ Martini PG, Katzenellenbogen Benita S (Jun 2003). "Modulation of estrogen receptor activity by selective coregulators". J. Steroid Biochem. Mol. Biol . 85 (2–5): 117–22.
doi :
10.1016/S0960-0760(03)00207-3 .
ISSN
0960-0760 .
PMID
12943695 .
S2CID
32374864 .
Further reading
Martini PG, Katzenellenbogen BS (2003). "Modulation of estrogen receptor activity by selective coregulators". J. Steroid Biochem. Mol. Biol . 85 (2–5): 117–22.
doi :
10.1016/S0960-0760(03)00207-3 .
PMID
12943695 .
S2CID
32374864 .
Ansari-Lari MA, Muzny DM, Lu J, et al. (1996).
"A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13" . Genome Res . 6 (4): 314–26.
doi :
10.1101/gr.6.4.314 .
PMID
8723724 .
Ansari-Lari MA, Shen Y, Muzny DM, et al. (1997).
"Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination" . Genome Res . 7 (3): 268–80.
doi :
10.1101/gr.7.3.268 .
PMID
9074930 .
Montano MM, Ekena K, Delage-Mourroux R, et al. (1999).
"An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens" . Proc. Natl. Acad. Sci. U.S.A . 96 (12): 6947–52.
Bibcode :
1999PNAS...96.6947M .
doi :
10.1073/pnas.96.12.6947 .
PMC
22022 .
PMID
10359819 .
Hu RM, Han ZG, Song HD, et al. (2000).
"Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning" . Proc. Natl. Acad. Sci. U.S.A . 97 (17): 9543–8.
Bibcode :
2000PNAS...97.9543H .
doi :
10.1073/pnas.160270997 .
PMC
16901 .
PMID
10931946 .
Martini PG, Delage-Mourroux R, Kraichely DM, Katzenellenbogen BS (2000).
"Prothymosin Alpha Selectively Enhances Estrogen Receptor Transcriptional Activity by Interacting with a Repressor of Estrogen Receptor Activity" . Mol. Cell. Biol . 20 (17): 6224–32.
doi :
10.1128/MCB.20.17.6224-6232.2000 .
PMC
86097 .
PMID
10938099 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol . 6 (2): 97–105.
doi :
10.1038/ncb1086 .
PMID
14743216 .
S2CID
11683986 .
Kurtev V, Margueron R, Kroboth K, et al. (2004).
"Transcriptional regulation by the repressor of estrogen receptor activity via recruitment of histone deacetylases" . J. Biol. Chem . 279 (23): 24834–43.
doi :
10.1074/jbc.M312300200 .
PMID
15140878 .
Lehner B, Sanderson CM (2004).
"A Protein Interaction Framework for Human mRNA Degradation" . Genome Res . 14 (7): 1315–23.
doi :
10.1101/gr.2122004 .
PMC
442147 .
PMID
15231747 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Rush J, Moritz A, Lee KA, et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol . 23 (1): 94–101.
doi :
10.1038/nbt1046 .
PMID
15592455 .
S2CID
7200157 .
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8.
Bibcode :
2005Natur.437.1173R .
doi :
10.1038/nature04209 .
PMID
16189514 .
S2CID
4427026 .
Scherer SE, Muzny DM, Buhay CJ, et al. (2006).
"The finished DNA sequence of human chromosome 12" . Nature . 440 (7082): 346–51.
Bibcode :
2006Natur.440..346S .
doi :
10.1038/nature04569 .
PMID
16541075 .
Kasashima K, Ohta E, Kagawa Y, Endo H (2007).
"Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2" . J. Biol. Chem . 281 (47): 36401–10.
doi :
10.1074/jbc.M605260200 .
PMID
17008324 .
Ewing RM, Chu P, Elisma F, et al. (2007).
"Large-scale mapping of human protein–protein interactions by mass spectrometry" . Mol. Syst. Biol . 3 (1): 89.
doi :
10.1038/msb4100134 .
PMC
1847948 .
PMID
17353931 .
Takata H, Matsunaga S, Morimoto A, et al. (2007).
"PHB2 protects sister-chromatid cohesion in mitosis" . Curr. Biol . 17 (15): 1356–61.
Bibcode :
2007CBio...17.1356T .
doi :
10.1016/j.cub.2007.07.009 .
PMID
17656096 .
S2CID
18987683 .