PDX may refer to:

• Portland, Oregon, US
  • Portland International Airport (IATA code)
  • Portland Union Station (railway code)

• PDX, a line of musical instruments and equipment by Vestax
• Paradox Interactive, a Swedish video game publisher
  • Paradox Development Studio, the in-house game development team of the above

• Paradox (warez), a warez–demogroup; an anonymous group of software engineers that devise ways to defeat software and video game licensing protections, a process known as cracking

• Pancreatic and duodenal homeobox protein, a transcription factor
• Patient-derived xenograft, human tumor grown in mice
• PDX, principal diagnosis (see Medical diagnosis#Concepts related to diagnosis), the main cause of a patient's need for treatment

• PDX.edu, domain name of Portland State University, Oregon
• Performance Driving eXperience, an event sanctioned by the Sports Car Club of America

• KPDX, a television station in the Portland, Oregon area

This disambiguation page lists articles associated with the title PDX.
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