Names | |
---|---|
IUPAC name
4-methylbenzenesulfonohydrazide
| |
Other names
tosyl hydrazide
| |
Identifiers | |
3D model (
JSmol)
|
|
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.014.917 |
EC Number |
|
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
Appearance | white solid |
Melting point | 108–110 °C (226–230 °F; 381–383 K) |
Hazards | |
GHS labelling: | |
Danger | |
H242, H301, H302, H315, H317, H319, H341, H373, H410 | |
P201, P202, P210, P220, P234, P260, P261, P264, P270, P272, P273, P280, P281, P301+P310, P301+P312, P302+P352, P305+P351+P338, P308+P313, P314, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P370+P378, P391, P403+P235, P405, P411, P420, P501 | |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
p-Toluenesulfonyl hydrazide is the organic compound with the formula CH3C6H4SO2NHNH2. It is a white solid that is soluble in many organic solvents but not water or alkanes. It is a reagent in organic synthesis. [1]
With ketones and aldehydes, it condenses to give the hydrazones:
Upon heating in solution, it degrades, releasing diimide (N2H2), a useful reducing agent. Triisopropylbenzenesulfonylhydrazide is far more useful for this reaction.
Toluenesulfonyl hydrazide is prepared by the reaction of a toluenesulfonyl chloride with hydrazine: [2]
Tosylhydrazides can be installed by nucleophilic attack and later removed by base. It thus provides a way to covert C-Cl to C-H. [3]
Names | |
---|---|
IUPAC name
4-methylbenzenesulfonohydrazide
| |
Other names
tosyl hydrazide
| |
Identifiers | |
3D model (
JSmol)
|
|
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.014.917 |
EC Number |
|
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
Appearance | white solid |
Melting point | 108–110 °C (226–230 °F; 381–383 K) |
Hazards | |
GHS labelling: | |
Danger | |
H242, H301, H302, H315, H317, H319, H341, H373, H410 | |
P201, P202, P210, P220, P234, P260, P261, P264, P270, P272, P273, P280, P281, P301+P310, P301+P312, P302+P352, P305+P351+P338, P308+P313, P314, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P370+P378, P391, P403+P235, P405, P411, P420, P501 | |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
p-Toluenesulfonyl hydrazide is the organic compound with the formula CH3C6H4SO2NHNH2. It is a white solid that is soluble in many organic solvents but not water or alkanes. It is a reagent in organic synthesis. [1]
With ketones and aldehydes, it condenses to give the hydrazones:
Upon heating in solution, it degrades, releasing diimide (N2H2), a useful reducing agent. Triisopropylbenzenesulfonylhydrazide is far more useful for this reaction.
Toluenesulfonyl hydrazide is prepared by the reaction of a toluenesulfonyl chloride with hydrazine: [2]
Tosylhydrazides can be installed by nucleophilic attack and later removed by base. It thus provides a way to covert C-Cl to C-H. [3]