^Weiss, Andreas; Lorthiois, Edwige; Barys, Louise; Beyer, Kim S.; Bomio-Confaglia, Claudio; Burks, Heather; Chen, Xueying; Cui, Xiaoming; de Kanter, Ruben; Dharmarajan, Lekshmi; Fedele, Carmine; Gerspacher, Marc; Guthy, Daniel Alexander; Head, Victoria; Jaeger, Ashley; Núñez, Eloísa Jiménez; Kearns, Jeffrey D.; Leblanc, Catherine; Maira, Sauveur-Michel; Murphy, Jason; Oakman, Helen; Ostermann, Nils; Ottl, Johannes; Rigollier, Pascal; Roman, Danielle; Schnell, Christian; Sedrani, Richard; Shimizu, Toshio; Stringer, Rowan; Vaupel, Andrea; Voshol, Hans; Wessels, Peter; Widmer, Toni; Wilcken, Rainer; Xu, Kun; Zecri, Frederic; Farago, Anna F.; Cotesta, Simona; Brachmann, Saskia M. (2 June 2022).
"Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C". Cancer Discovery. 12 (6): 1500–1517.
doi:10.1158/2159-8290.CD-22-0158.
PMID35404998.
^Lorthiois, Edwige; Gerspacher, Marc; Beyer, Kim S.; Vaupel, Andrea; Leblanc, Catherine; Stringer, Rowan; Weiss, Andreas; Wilcken, Rainer; Guthy, Daniel A.; Lingel, Andreas; Bomio-Confaglia, Claudio; Machauer, Rainer; Rigollier, Pascal; Ottl, Johannes; Arz, Dorothee; Bernet, Pascal; Desjonqueres, Gaëlle; Dussauge, Solene; Kazic-Legueux, Malika; Lozac’h, Marie-Anne; Mura, Christophe; Sorge, Mickaël; Todorov, Milen; Warin, Nicolas; Zink, Florence; Voshol, Hans; Zecri, Frederic J.; Sedrani, Richard C.; Ostermann, Nils; Brachmann, Saskia M.; Cotesta, Simona (22 December 2022). "JDQ443, a Structurally Novel, Pyrazole-Based, Covalent Inhibitor of KRAS G12C for the Treatment of Solid Tumors". Journal of Medicinal Chemistry. 65 (24): 16173–16203.
doi:
10.1021/acs.jmedchem.2c01438.
PMID36399068.
S2CID253626954.
^Lindsay, Colin R; Veluswamy, Rajwanth; Castro, Gilberto; Tan, Daniel Shao-Weng; Caparica, Rafael; Glaser, Sabine; Malhotra, Shweta; Boran, Aislyn; Felip, Enriqueta (1 June 2023). "A phase II trial of JDQ443 in KRAS G12C -mutated NSCLC with PD-L1 expression". Journal of Clinical Oncology. 41 (16_suppl): TPS9158.
doi:
10.1200/JCO.2023.41.16_suppl.TPS9158.
S2CID258169371.
^Cassier, Philippe Alexandre; Dooms, Christophe Alfons; Gazzah, Anas; Felip, Enriqueta; Steeghs, Neeltje; Rohrberg, Kristoffer Staal; De Braud, Filippo G.; Solomon, Benjamin J.; Schuler, Martin H.; Tan, Daniel Shao-Weng; Yamamoto, Noboru; Loong, Herbert H. F.; Cho, Byoung Chul; Wolf, Juergen; Lin, Chia-Chi; Negrao, Marcelo Vailati; Werner, Lillian; Cui, Xiaoming; Farago, Anna F.; de Miguel, Maria J. (1 June 2023). "KontRASt-01 update: Safety and efficacy of JDQ443 in KRAS G12C -mutated solid tumors including non-small cell lung cancer (NSCLC)". Journal of Clinical Oncology. 41 (16_suppl): 9007.
doi:
10.1200/JCO.2023.41.16_suppl.9007.
S2CID259079866.
^Weiss, Andreas; Lorthiois, Edwige; Barys, Louise; Beyer, Kim S.; Bomio-Confaglia, Claudio; Burks, Heather; Chen, Xueying; Cui, Xiaoming; de Kanter, Ruben; Dharmarajan, Lekshmi; Fedele, Carmine; Gerspacher, Marc; Guthy, Daniel Alexander; Head, Victoria; Jaeger, Ashley; Núñez, Eloísa Jiménez; Kearns, Jeffrey D.; Leblanc, Catherine; Maira, Sauveur-Michel; Murphy, Jason; Oakman, Helen; Ostermann, Nils; Ottl, Johannes; Rigollier, Pascal; Roman, Danielle; Schnell, Christian; Sedrani, Richard; Shimizu, Toshio; Stringer, Rowan; Vaupel, Andrea; Voshol, Hans; Wessels, Peter; Widmer, Toni; Wilcken, Rainer; Xu, Kun; Zecri, Frederic; Farago, Anna F.; Cotesta, Simona; Brachmann, Saskia M. (2 June 2022).
"Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C". Cancer Discovery. 12 (6): 1500–1517.
doi:10.1158/2159-8290.CD-22-0158.
PMID35404998.
^Lorthiois, Edwige; Gerspacher, Marc; Beyer, Kim S.; Vaupel, Andrea; Leblanc, Catherine; Stringer, Rowan; Weiss, Andreas; Wilcken, Rainer; Guthy, Daniel A.; Lingel, Andreas; Bomio-Confaglia, Claudio; Machauer, Rainer; Rigollier, Pascal; Ottl, Johannes; Arz, Dorothee; Bernet, Pascal; Desjonqueres, Gaëlle; Dussauge, Solene; Kazic-Legueux, Malika; Lozac’h, Marie-Anne; Mura, Christophe; Sorge, Mickaël; Todorov, Milen; Warin, Nicolas; Zink, Florence; Voshol, Hans; Zecri, Frederic J.; Sedrani, Richard C.; Ostermann, Nils; Brachmann, Saskia M.; Cotesta, Simona (22 December 2022). "JDQ443, a Structurally Novel, Pyrazole-Based, Covalent Inhibitor of KRAS G12C for the Treatment of Solid Tumors". Journal of Medicinal Chemistry. 65 (24): 16173–16203.
doi:
10.1021/acs.jmedchem.2c01438.
PMID36399068.
S2CID253626954.
^Lindsay, Colin R; Veluswamy, Rajwanth; Castro, Gilberto; Tan, Daniel Shao-Weng; Caparica, Rafael; Glaser, Sabine; Malhotra, Shweta; Boran, Aislyn; Felip, Enriqueta (1 June 2023). "A phase II trial of JDQ443 in KRAS G12C -mutated NSCLC with PD-L1 expression". Journal of Clinical Oncology. 41 (16_suppl): TPS9158.
doi:
10.1200/JCO.2023.41.16_suppl.TPS9158.
S2CID258169371.
^Cassier, Philippe Alexandre; Dooms, Christophe Alfons; Gazzah, Anas; Felip, Enriqueta; Steeghs, Neeltje; Rohrberg, Kristoffer Staal; De Braud, Filippo G.; Solomon, Benjamin J.; Schuler, Martin H.; Tan, Daniel Shao-Weng; Yamamoto, Noboru; Loong, Herbert H. F.; Cho, Byoung Chul; Wolf, Juergen; Lin, Chia-Chi; Negrao, Marcelo Vailati; Werner, Lillian; Cui, Xiaoming; Farago, Anna F.; de Miguel, Maria J. (1 June 2023). "KontRASt-01 update: Safety and efficacy of JDQ443 in KRAS G12C -mutated solid tumors including non-small cell lung cancer (NSCLC)". Journal of Clinical Oncology. 41 (16_suppl): 9007.
doi:
10.1200/JCO.2023.41.16_suppl.9007.
S2CID259079866.