Nodular sclerosis | |
---|---|
![]() | |
Nodular sclerosis. The distinct nodules on the cut surface of this lymph node strongly suggest the diagnosis. | |
Specialty |
Oncology
![]() |
Nodular sclerosis (or "NSHL") is a form of Hodgkin's lymphoma [1] that is the most common subtype of HL in developed countries. It affects females slightly more than males and has a median age of onset at ~28 years. It is composed of large tumor nodules with lacunar Reed–Sternberg cell (RS cells) surrounded by fibrotic collagen bands.[ citation needed]
The British National Lymphoma Investigation further categorized NSHL based upon Reed-Sternberg cells into "nodular sclerosis type I" (NS I) and "nodular sclerosis type II" (NS II), with the first subtype responding better to treatment. [2]
Nodular sclerosis | |
---|---|
![]() | |
Nodular sclerosis. The distinct nodules on the cut surface of this lymph node strongly suggest the diagnosis. | |
Specialty |
Oncology
![]() |
Nodular sclerosis (or "NSHL") is a form of Hodgkin's lymphoma [1] that is the most common subtype of HL in developed countries. It affects females slightly more than males and has a median age of onset at ~28 years. It is composed of large tumor nodules with lacunar Reed–Sternberg cell (RS cells) surrounded by fibrotic collagen bands.[ citation needed]
The British National Lymphoma Investigation further categorized NSHL based upon Reed-Sternberg cells into "nodular sclerosis type I" (NS I) and "nodular sclerosis type II" (NS II), with the first subtype responding better to treatment. [2]