Nanoimpellers are an experimental technology developed to eliminate some of the harmful effects of chemotherapy by facilitating treatment of only specific areas of the body. Nanoimpellers are nanoscale, light-activated containers filled with cancer-fighting drugs that only release their contents when hit by a specific type of laser. [1]
Nanoimpellers for cancer drug delivery were first demonstrated in 2008. [2] [3] Initial work used ultraviolet light, however the low penetration in tissue and potential for toxicity mean this is not well suited for delivery in patients. [1] Later work has shifted to using near infrared light and two photon excitation (TPE) to trigger release. [4] [5]
Nanoimpellers are an experimental technology developed to eliminate some of the harmful effects of chemotherapy by facilitating treatment of only specific areas of the body. Nanoimpellers are nanoscale, light-activated containers filled with cancer-fighting drugs that only release their contents when hit by a specific type of laser. [1]
Nanoimpellers for cancer drug delivery were first demonstrated in 2008. [2] [3] Initial work used ultraviolet light, however the low penetration in tissue and potential for toxicity mean this is not well suited for delivery in patients. [1] Later work has shifted to using near infrared light and two photon excitation (TPE) to trigger release. [4] [5]