From Wikipedia, the free encyclopedia

NUMBL
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases NUMBL, CAG3A, CTG3a, NBL, NUMB-R, NUMBLIKE, NUMBR, TNRC23, NUMB like, endocytic adaptor protein, NUMB like endocytic adaptor protein
External IDs OMIM: 604018; MGI: 894702; HomoloGene: 68413; GeneCards: NUMBL; OMA: NUMBL - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001289979
NM_001289980
NM_004756

NM_010950

RefSeq (protein)

NP_001276908
NP_001276909
NP_004747

NP_035080

Location (UCSC) Chr 19: 40.67 – 40.69 Mb Chr 7: 26.96 – 26.98 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Numb-like protein is a protein that in humans is encoded by the NUMBL gene. [5] [6] [7]


Interactions

NUMBL has been shown to interact with MAP3K7IP2. [8]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000105245Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000063160Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Margolis RL, Abraham MR, Gatchell SB, Li SH, Kidwai AS, Breschel TS, Stine OC, Callahan C, McInnis MG, Ross CA (Jul 1997). "cDNAs with long CAG trinucleotide repeats from human brain". Hum Genet. 100 (1): 114–22. doi: 10.1007/s004390050476. PMID  9225980. S2CID  25999127.
  6. ^ Salcini AE, Confalonieri S, Doria M, Santolini E, Tassi E, Minenkova O, Cesareni G, Pelicci PG, Di Fiore PP (Oct 1997). "Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module". Genes Dev. 11 (17): 2239–49. doi: 10.1101/gad.11.17.2239. PMC  275390. PMID  9303539.
  7. ^ "Entrez Gene: NUMBL numb homolog (Drosophila)-like".
  8. ^ Ma Q, Zhou Li, Shi Huili, Huo Keke (Jun 2008). "NUMBL interacts with TAB2 and inhibits TNFalpha and IL-1beta-induced NF-kappaB activation". Cell. Signal. 20 (6). England: 1044–51. doi: 10.1016/j.cellsig.2008.01.015. ISSN  0898-6568. PMID  18299187.

Further reading


From Wikipedia, the free encyclopedia

NUMBL
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases NUMBL, CAG3A, CTG3a, NBL, NUMB-R, NUMBLIKE, NUMBR, TNRC23, NUMB like, endocytic adaptor protein, NUMB like endocytic adaptor protein
External IDs OMIM: 604018; MGI: 894702; HomoloGene: 68413; GeneCards: NUMBL; OMA: NUMBL - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001289979
NM_001289980
NM_004756

NM_010950

RefSeq (protein)

NP_001276908
NP_001276909
NP_004747

NP_035080

Location (UCSC) Chr 19: 40.67 – 40.69 Mb Chr 7: 26.96 – 26.98 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Numb-like protein is a protein that in humans is encoded by the NUMBL gene. [5] [6] [7]


Interactions

NUMBL has been shown to interact with MAP3K7IP2. [8]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000105245Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000063160Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Margolis RL, Abraham MR, Gatchell SB, Li SH, Kidwai AS, Breschel TS, Stine OC, Callahan C, McInnis MG, Ross CA (Jul 1997). "cDNAs with long CAG trinucleotide repeats from human brain". Hum Genet. 100 (1): 114–22. doi: 10.1007/s004390050476. PMID  9225980. S2CID  25999127.
  6. ^ Salcini AE, Confalonieri S, Doria M, Santolini E, Tassi E, Minenkova O, Cesareni G, Pelicci PG, Di Fiore PP (Oct 1997). "Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module". Genes Dev. 11 (17): 2239–49. doi: 10.1101/gad.11.17.2239. PMC  275390. PMID  9303539.
  7. ^ "Entrez Gene: NUMBL numb homolog (Drosophila)-like".
  8. ^ Ma Q, Zhou Li, Shi Huili, Huo Keke (Jun 2008). "NUMBL interacts with TAB2 and inhibits TNFalpha and IL-1beta-induced NF-kappaB activation". Cell. Signal. 20 (6). England: 1044–51. doi: 10.1016/j.cellsig.2008.01.015. ISSN  0898-6568. PMID  18299187.

Further reading



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