| |
| Names | |
|---|---|
|
Preferred IUPAC name
2-(Cyclohexylamino)ethane-1-sulfonic acid | |
| Other names
N-Cyclohexyl-2-aminoethanesulfonic acid; N-Cyclohexyltaurine
| |
| Identifiers | |
3D model (
JSmol)
|
|
| ChEBI | |
| ChemSpider | |
| DrugBank | |
| ECHA InfoCard | 100.002.832 |
| MeSH | 2-(N-cyclohexylamino)ethanesulfonic+acid |
PubChem
CID
|
|
| UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
| Properties | |
| C8H17NO3S | |
| Molar mass | 207.29 g·mol−1 |
| Acidity (pKa) | 9.3 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
| |
CHES (N-cyclohexyl-2-aminoethanesulfonic acid) is a buffering agent. CHES buffers have a useful range of pH 8.6–10. [1]
It typically appears as a white crystalline powder.
Effect of impurities
Commercial prep of CHES (and other sulfonylethyl buffers like MES, BES, and PIPES) can contain a contaminant oligo(vinylsulfonic acid) (OVS), which is a polyanionic mimic of RNA, and can be a potent ( pM) inhibitor of RNA binding proteins and enzymes. [2]
References
- ^ "Good's buffers (biological buffers)" (PDF).
- ^ Smith, Bryan D.; Soellner, Matthew B.; Raines, Ronald T. (2003). "Potent Inhibition of Ribonuclease A by Oligo(vinylsulfonic Acid)". Journal of Biological Chemistry. 278 (23). Elsevier BV: 20934–20938. doi: 10.1074/jbc.m301852200. ISSN 0021-9258.
External links
 | This article about an organic compound is a stub. You can help Wikipedia by expanding it. |
|
| |
| Names | |
|---|---|
|
Preferred IUPAC name
2-(Cyclohexylamino)ethane-1-sulfonic acid | |
| Other names
N-Cyclohexyl-2-aminoethanesulfonic acid; N-Cyclohexyltaurine
| |
| Identifiers | |
3D model (
JSmol)
|
|
| ChEBI | |
| ChemSpider | |
| DrugBank | |
| ECHA InfoCard | 100.002.832 |
| MeSH | 2-(N-cyclohexylamino)ethanesulfonic+acid |
PubChem
CID
|
|
| UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
| Properties | |
| C8H17NO3S | |
| Molar mass | 207.29 g·mol−1 |
| Acidity (pKa) | 9.3 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
| |
CHES (N-cyclohexyl-2-aminoethanesulfonic acid) is a buffering agent. CHES buffers have a useful range of pH 8.6–10. [1]
It typically appears as a white crystalline powder.
Effect of impurities
Commercial prep of CHES (and other sulfonylethyl buffers like MES, BES, and PIPES) can contain a contaminant oligo(vinylsulfonic acid) (OVS), which is a polyanionic mimic of RNA, and can be a potent ( pM) inhibitor of RNA binding proteins and enzymes. [2]
References
- ^ "Good's buffers (biological buffers)" (PDF).
- ^ Smith, Bryan D.; Soellner, Matthew B.; Raines, Ronald T. (2003). "Potent Inhibition of Ribonuclease A by Oligo(vinylsulfonic Acid)". Journal of Biological Chemistry. 278 (23). Elsevier BV: 20934–20938. doi: 10.1074/jbc.m301852200. ISSN 0021-9258.
External links
|
| This article about an organic compound is a stub. You can help Wikipedia by expanding it. |