Names | |
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IUPAC name
3-[(3R,6R,9R,12R,15S,22S,25S,30aS)-6,9,15,22-Tetrakis(2-amino-2-oxoethyl)-3-(4-hydroxybenzyl)-12-(hydroxymethyl)-18-(11-methyltridecyl)-1,4,7,10,13,16,20,23,26-nonaoxotriacontahydropyrrolo[1,2-g] [1,4,7,10,13,16,19,22,25]nonaazacyclooctacosin-25-yl]propanamide
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Identifiers | |
3D model (
JSmol)
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ChemSpider | |
PubChem
CID
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Properties | |
C55H86N14O16 | |
Molar mass | 1199.375 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Mycosubtilin is a natural lipopeptide with antifungal and hemolytic activities and isolated from Bacillus species. It belongs to the iturin lipopeptide family.
Mycosubtilin is a natural lipopeptide. It is produced by the strains of Bacillus spp mainly by Bacillus subtilis. It was discovered due to its antifungal activities. [1] It belongs to the family of iturin lipopeptides [2]
Mycosubtilin is a heptapeptide, cyclized in a ring with a β-amino fatty acid. [3] The peptide sequence is composed of L-Asn-D-Tyr-D-Asn-L-Gln-L-Pro-D-Ser-L-Asn. [4]
Mycosubtilin has strong antifungal and hemolytic activities. [5] [6] It is active against fungi and yeasts such as Candida albicans, Candida tropicalis, Saccharomyces cerevisiae, Penicillium notatum, and Fusarium oxysporum. [7] [8] [9]
Its antibacterial activity is quite limited to bacteria such as Micrococcus luteus. [10]
Names | |
---|---|
IUPAC name
3-[(3R,6R,9R,12R,15S,22S,25S,30aS)-6,9,15,22-Tetrakis(2-amino-2-oxoethyl)-3-(4-hydroxybenzyl)-12-(hydroxymethyl)-18-(11-methyltridecyl)-1,4,7,10,13,16,20,23,26-nonaoxotriacontahydropyrrolo[1,2-g] [1,4,7,10,13,16,19,22,25]nonaazacyclooctacosin-25-yl]propanamide
| |
Identifiers | |
3D model (
JSmol)
|
|
ChemSpider | |
PubChem
CID
|
|
| |
| |
Properties | |
C55H86N14O16 | |
Molar mass | 1199.375 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Mycosubtilin is a natural lipopeptide with antifungal and hemolytic activities and isolated from Bacillus species. It belongs to the iturin lipopeptide family.
Mycosubtilin is a natural lipopeptide. It is produced by the strains of Bacillus spp mainly by Bacillus subtilis. It was discovered due to its antifungal activities. [1] It belongs to the family of iturin lipopeptides [2]
Mycosubtilin is a heptapeptide, cyclized in a ring with a β-amino fatty acid. [3] The peptide sequence is composed of L-Asn-D-Tyr-D-Asn-L-Gln-L-Pro-D-Ser-L-Asn. [4]
Mycosubtilin has strong antifungal and hemolytic activities. [5] [6] It is active against fungi and yeasts such as Candida albicans, Candida tropicalis, Saccharomyces cerevisiae, Penicillium notatum, and Fusarium oxysporum. [7] [8] [9]
Its antibacterial activity is quite limited to bacteria such as Micrococcus luteus. [10]