MORC family CW-type zinc finger 1 is a protein that in humans is encoded by the MORC1 gene. [5]
Function
This gene encodes the human homolog of mouse morc and like the mouse protein it is testis-specific. Mouse studies support a testis-specific function since only male knockout mice are infertile; infertility is the only apparent defect. These studies further support a role for this protein early in spermatogenesis, possibly by affecting entry into apoptosis because testis from knockout mice show greatly increased numbers of apoptotic cells. [provided by RefSeq, Jan 2009].
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000114487 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022652 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: MORC family CW-type zinc finger 1". Retrieved 2018-07-12.
Further reading
- Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi: 10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
 | This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it. |
| MORC1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | MORC1, CT33, MORC, ZCW6, MORC family CW-type zinc finger 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 603205; MGI: 1316740; HomoloGene: 7843; GeneCards: MORC1; OMA: MORC1 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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MORC family CW-type zinc finger 1 is a protein that in humans is encoded by the MORC1 gene. [5]
Function
This gene encodes the human homolog of mouse morc and like the mouse protein it is testis-specific. Mouse studies support a testis-specific function since only male knockout mice are infertile; infertility is the only apparent defect. These studies further support a role for this protein early in spermatogenesis, possibly by affecting entry into apoptosis because testis from knockout mice show greatly increased numbers of apoptotic cells. [provided by RefSeq, Jan 2009].
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000114487 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022652 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: MORC family CW-type zinc finger 1". Retrieved 2018-07-12.
Further reading
- Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi: 10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
|
| This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it. |