Monica Riley | |
---|---|
Born | 1926 |
Died | October 11, 2013 | (aged 86–87)
Citizenship | American |
Alma mater | Smith College, University of California Berkeley |
Known for | Messenger RNA, Escherichia coli genome |
Scientific career | |
Institutions | University of California Davis, Stony Brook University, Marine Biological Laboratory in Woods Hole |
Thesis | Selective destruction of genetic material and its effect on ¹-galactosidase synthesis in Escherichia coli (1960) |
Monica Riley (1926 – October 11, 2013) was an American scientist who contributed to the discovery of messenger RNA in her Ph.D work with Arthur Pardee, and was later a pioneer in the exploration and computer representation of the Escherichia coli genome.
After graduating from Smith College with a chemistry degree in 1947, she studied Biochemistry at University of California Berkeley with Pardee. [1] [2] Her Ph.D. work, together with the PaJaMo experiment, ruled out ribosomes as carriers of information to synthesize protein, leading to the discovery of messenger RNA. [3] After holding faculty positions at University of California Davis and Stony Brook University, she moved to the Marine Biological Laboratory in Woods Hole, staying there until age 80. [2]
As a senior scientist at MBL she was one of the four founding faculty members of the Josephine Bay Paul Center for Comparative Molecular Biology and Evolution led by Mitchell Sogin. [4] During this time, she co-founded the EcoCyc database of Escherichia coli metabolism, [5] leading the curation of metabolic pathways and genome information for Escherichia coli for over a decade, [6] and developed classification systems for genes and proteins (including MultiFun), which were forerunners of gene ontology. [1] [2]
Monica Riley | |
---|---|
Born | 1926 |
Died | October 11, 2013 | (aged 86–87)
Citizenship | American |
Alma mater | Smith College, University of California Berkeley |
Known for | Messenger RNA, Escherichia coli genome |
Scientific career | |
Institutions | University of California Davis, Stony Brook University, Marine Biological Laboratory in Woods Hole |
Thesis | Selective destruction of genetic material and its effect on ¹-galactosidase synthesis in Escherichia coli (1960) |
Monica Riley (1926 – October 11, 2013) was an American scientist who contributed to the discovery of messenger RNA in her Ph.D work with Arthur Pardee, and was later a pioneer in the exploration and computer representation of the Escherichia coli genome.
After graduating from Smith College with a chemistry degree in 1947, she studied Biochemistry at University of California Berkeley with Pardee. [1] [2] Her Ph.D. work, together with the PaJaMo experiment, ruled out ribosomes as carriers of information to synthesize protein, leading to the discovery of messenger RNA. [3] After holding faculty positions at University of California Davis and Stony Brook University, she moved to the Marine Biological Laboratory in Woods Hole, staying there until age 80. [2]
As a senior scientist at MBL she was one of the four founding faculty members of the Josephine Bay Paul Center for Comparative Molecular Biology and Evolution led by Mitchell Sogin. [4] During this time, she co-founded the EcoCyc database of Escherichia coli metabolism, [5] leading the curation of metabolic pathways and genome information for Escherichia coli for over a decade, [6] and developed classification systems for genes and proteins (including MultiFun), which were forerunners of gene ontology. [1] [2]