Moco (molybdenum cofactor) riboswitch | |
---|---|
Identifiers | |
Symbol | MOCO_RNA_motif |
Rfam | RF01055 |
Other data | |
RNA type | Cis-reg; riboswitch |
Domain(s) | Bacteria |
SO | SO:0005836 |
PDB structures | PDBe |
The Moco RNA motif is a conserved RNA structure [1] that is presumed to be a riboswitch that binds molybdenum cofactor or the related tungsten cofactor. Genetic experiments support the hypothesis that the Moco RNA motif corresponds to a genetic control element that responds to changing concentrations of molybdenum or tungsten cofactor. [2] As these cofactors are not available in purified form, in vitro binding assays cannot be performed. However, the genetic data, complex structure of the RNA and the failure to detect a protein involved in the regulation suggest that the Moco RNA motif corresponds to a class of riboswitches.
Moco (molybdenum cofactor) riboswitch | |
---|---|
Identifiers | |
Symbol | MOCO_RNA_motif |
Rfam | RF01055 |
Other data | |
RNA type | Cis-reg; riboswitch |
Domain(s) | Bacteria |
SO | SO:0005836 |
PDB structures | PDBe |
The Moco RNA motif is a conserved RNA structure [1] that is presumed to be a riboswitch that binds molybdenum cofactor or the related tungsten cofactor. Genetic experiments support the hypothesis that the Moco RNA motif corresponds to a genetic control element that responds to changing concentrations of molybdenum or tungsten cofactor. [2] As these cofactors are not available in purified form, in vitro binding assays cannot be performed. However, the genetic data, complex structure of the RNA and the failure to detect a protein involved in the regulation suggest that the Moco RNA motif corresponds to a class of riboswitches.