The MichaelisâBecker reaction is the reaction of a hydrogen phosphonate with a base, followed by a nucleophilic substitution of phosphorus on a haloalkane, to give an alkyl phosphonate. Yields of this reaction are often lower than the corresponding MichaelisâArbuzov reaction. [1] [2]
The MichaelisâBecker reaction is the reaction of a hydrogen phosphonate with a base, followed by a nucleophilic substitution of phosphorus on a haloalkane, to give an alkyl phosphonate. Yields of this reaction are often lower than the corresponding MichaelisâArbuzov reaction. [1] [2]